First steps towards sustainability? University freshmen perceptions on nature versus environment

The Global Earth Overshoot Day, the date when all annually available natural resources are consumed, is set for July this year. For densely populated European countries like Germany or Switzerland, that specific day is due even earlier (May). To overcome such an unsustainable lifestyle, immediate actions are required, which includes substantial educational efforts. As the model of "Sustainable Development" is complex, appropriate pedagogical actions need to support cognitive learning, critical thinking and behavioural actions. Knowledge about individual conceptions in relation to the Environment, Nature and Ecological Footprints contributes to pre-conditions to succeed. To what extent present teaching methods influenced individual conceptions during the first UN-decade regarding those terms is illustrated by 464 Swiss-German university freshmen who participated in our paper-pencil test, which is based on four open questions. The term of Environment was perceived as the sum of biocentric, ecocentric and anthropocentric views. The participants often equated the term to Nature and associated it with positive feelings or emotions. Therefore, calm, joy and aesthetic appreciation were predominantly named. Regardless of the concept, humans were perceived as the Greatest Environmental Threat. In contrast, recommendations to reduce Environmental Footprints regarding mobility & transport, waste avoidance and consumption differ. Following a binary logistic regression analysis, the involvement of the Inclusion of Self Scale (INS) was used as an explanatory variable to detect patterns of those conceptions. Relating sustainable concepts, natural resources were frequently named exceeding saving water and energy or other association dealt with second-hand issues or regional/ seasonal usages. Such ideas are shaped by experiences and scientific expertise

Die Kreisgrabenanlage von Rosenburg, NÖ

Diese Arbeit beschäftigt sich mit der Neubearbeitung und Aufarbeitung, sowie der zeitlichen Einordnung des Keramikmaterials der Kreisgrabenanlage von Rosenburg im Ger.- Bez. und politischen Bezirk Horn, Niederösterreich. Die Fundstelle befindet sich am nordwestlichen Ende der Ortschaft Rosenburg. Die Kreisgrabenanlage wurde von 1987-1989 im Zuge einer Forschungsgrabung unter der Leitung von Univ.-Prof. Dr. Gerhard Trnka von der Universität Wien untersucht. Die Befunde in Rosenburg erfüllen alle wichtigen Kriterien um als Kreisgrabenanlage angesprochen zu werden. Der Grabenverlauf ist konzentrisch und der Graben I hat einen v-förmigen Querschnitt. Es konnten ebenso zwei Eingänge/Toranlagen festgestellt werden. Insgesamt wurden 10 Grabungsschnitte untersucht. Im ersten Grabungsjahr wurden die Schnitte 1-5 freigelegt. Im zweiten Grabungsjahr folgten die Schnitte 6-8 und drittem Grabungsjahr wurden die Schnitte 9-10 angelegt. In den drei Grabungsjahren wurden insgesamt 30 neolithische Befunde freigelegt. Darunter befinden sich der Großteil des Grabensystems und zahlreiche Gruben, sowie die zwei Pfostengräbchen II & III. Die Fundzusammensetzung datiert die Kreisgrabenanlage in das Frühlengyel Ia (Stufe Langenzersdorf/Kamegg)

Green Awareness in Action : How Energy Conservation Action Forces on Environmental Knowledge, Values and Behaviour in Adolescents’ School Life

Affordable, reliable, sustainable and modern energy consumption is a crucial goal of the Agenda 2030. To raise each citizen’s awareness for more effective energy consumptions, proper education is necessary. The classroom project GAIA (Green Awareness in Action) was designed to change energy consumption patterns to pursue green behaviour. The class-wise aim was to improve schools’ CO2-balance and to promote environmentally sustainable behaviour without impacting school life quality. Our target group were sixth graders (N = 132, M = 11.03, SD ± 0.23, 53.4% = girls) of one Greek school. To monitor the project’s effect, a pre- and post-test design was applied to measure environmental literacy regarding environmental knowledge, attitudes/values and behaviour. A regression analysis revealed that students with poor previous knowledge reached higher learning effects compared to those with good previous knowledge. Related to the environmental knowledge types, an ANCOVA analysis revealed a knowledge gain in action-related and effectiveness knowledge. The overall learning effect correlates positively with pro-environmental preference (high scores in preservation, low scores in utilisation) and negatively with weak pro-environmental preferences. Anthropocentric (utilitarian) preferences primarily focussing on nature exploitation have considerably decreased. The project illustrates how far individual behaviour can be targeted in green educational initiatives

MASCUP! Mask Surveillance & Adherence Project @ Stockton University

Stockton University was one of over 50 Colleges and Universities across the nation to participate in a study sponsored by the Centers for Disease Control to gauge compliance with mask wearing during the Spring 2021 semester. Five undergraduate Public Health students supervised by a Public Health Faculty member, observed mask wearing behaviors of individuals on campus over an 8-week period of time. Observations ranged from 40-90 minutes at various times of day and at 15 different locations on campus. During that time there were a total of 2,548 observations, of which 2,357 people were wearing masks. Of that group, 92.5%, were wearing the mask correctly. Other variables that were observed and recorded were type of mask and how masks were worn incorrectly along with possible explanations for this mistake. Results indicate the most common type of mask was cloth, with more than half (54%), while the most common mistake was not covering the nose. Although observers were unable to determine the exact reason, the following were observed for those not wearing masks from most to least: eating / drinking, then, outdoors / not within 6 ft of anyone, and finally exercise / playing a sport. Lastly, Stockton’s results are compared to all institutions that participated in the study

Inducible deletion of CDK4 and CDK6 – deciphering CDK4/6 inhibitor effects in the hematopoietic system

Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors are considered a breakthrough in cancer therapy. Currently approved for breast cancer treatment, CDK4/6 inhibitors are extensively tested in other cancer subtypes. Frequently observed side effects include hematological abnormalities such as reduced numbers of neutrophils, erythroid cells and platelets that are associated with anemia, bleeding and a higher risk of infections. In order to understand whether the adverse effects within the hematopoietic system are related to CDK4 or CDK6 we generated transgenic mice that lack either CDK4 or CDK6 in adult hematopoiesis. Anemia and perturbed erythroid differentiation are associated with the absence of CDK6 but did not manifest in CDK4- deficient mice. Total CDK6 knockout mice accumulate the most dormant fraction of hematopoietic stem cells due to an impaired exit of the quiescent state. We recapitulated this finding by deleting CDK6 in adult hematopoiesis. In addition, unlike total CDK6 knockout, all stem cell fractions were affected and increased in numbers. The deletion of CDK6 was also accompanied by neutropenia which is frequently seen in patients receiving CDK4/6 inhibitors. This was not the case in the absence of CDK4; CDK4 deficiency resulted in elevated numbers of myeloid progenitors without translating into numeric changes of differentiated myeloid cells. By using Cdk4fl/fl and Cdk6fl/fl mice we assign side effects of CDK4/6 inhibitors predominantly to the absence of CDK6. These mice represent a novel and powerful tool that will enable to study the distinct functions of CDK4 and CDK6 in a tissue-dependent manner

Exhaled Volatile Organic Compounds during Inflammation Induced by TNF-α in Ventilated Rats

Systemic inflammation alters the composition of exhaled breath, possibly helping clinicians diagnose conditions such as sepsis. We therefore evaluated changes in exhaled breath of rats given tumor necrosis factor-alpha (TNF-α). Thirty male Sprague-Dawley rats were randomly assigned to three groups (n = 10 each) with intravenous injections of normal saline (control), 200 µg·kg−1 bodyweight TNF-α (TNF-α-200), or 600 µg·kg−1 bodyweight TNF-α (TNF-α-600), and were observed for 24 h or until death. Animals were ventilated with highly-purified synthetic air to analyze exhaled air by multicapillary column–ion mobility spectrometry. Volatile organic compounds (VOCs) were identified from a database. We recorded blood pressure and cardiac output, along with cytokine plasma concentrations. Control rats survived the 24 h observation period, whereas mean survival time decreased to 22 h for TNF-α-200 and 23 h for TNF-α-600 rats. Mean arterial pressure decreased in TNF-α groups, whereas IL-6 increased, consistent with mild to moderate inflammation. Hundreds of VOCs were detected in exhalome. P-cymol increased by a factor-of-two 4 h after injection of TNF-α-600 compared to the control and TNF-α-200. We found that 1-butanol and 1-pentanol increased in both TNF-α groups after 20 h compared to the control. As breath analysis distinguishes between two doses of TNF-α and none, we conclude that it might help clinicians identify systemic inflammatio

Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study

Objectives. Racial factors play a significant role in SSc. We evaluated differences in SSc presentations between white patients (WP), Asian patients (AP) and black patients (BP) and analysed the effects of geographical locations.Methods. SSc characteristics of patients from the EUSTAR cohort were cross-sectionally compared across racial groups using survival and multiple logistic regression analyses.Results. The study included 9162 WP, 341 AP and 181 BP. AP developed the first non-RP feature faster than WP but slower than BP. AP were less frequently anti-centromere (ACA; odds ratio (OR) = 0.4, P < 0.001) and more frequently anti-topoisomerase-I autoantibodies (ATA) positive (OR = 1.2, P = 0.068), while BP were less likely to be ACA and ATA positive than were WP [OR(ACA) = 0.3, P < 0.001; OR(ATA) = 0.5, P = 0.020]. AP had less often (OR = 0.7, P = 0.06) and BP more often (OR = 2.7, P < 0.001) diffuse skin involvement than had WP.AP and BP were more likely to have pulmonary hypertension [OR(AP) = 2.6, P < 0.001; OR(BP) = 2.7, P = 0.03 vs WP] and a reduced forced vital capacity [OR(AP) = 2.5, P < 0.001; OR(BP) = 2.4, P < 0.004] than were WP. AP more often had an impaired diffusing capacity of the lung than had BP and WP [OR(AP vs BP) = 1.9, P = 0.038; OR(AP vs WP) = 2.4, P < 0.001]. After RP onset, AP and BP had a higher hazard to die than had WP [hazard ratio (HR) (AP) = 1.6, P = 0.011; HR(BP) = 2.1, P < 0.001].Conclusion. Compared with WP, and mostly independent of geographical location, AP have a faster and earlier disease onset with high prevalences of ATA, pulmonary hypertension and forced vital capacity impairment and higher mortality. BP had the fastest disease onset, a high prevalence of diffuse skin involvement and nominally the highest mortality