Angiotensin-I converting enzyme I/D polymorphism associated with diabetes mellitus affects the severity of coronary artery disease

WOS: 000251886600090

Successful Treatment of Aluminum Phosphide Poisoning with Continuous Veno-venous Hemofiltration: A Case Report

WOS: 000381858100005Introduction: We aim to discuss the case of a patient with aluminum phosphide (AP) poisoning in a suicide attempt and who was successfully treated with continuous veno-venous hemofiltration (CVVH). Case Report: A-24-year old lady was admitted to a hospital with the complaints of dizziness, numbness in the face, and nausea and vomiting after taking two tablets of AP. She was transferred to our emergency clinic 10 h later because of persistent hypotension and metabolic acidosis. Her Glasgow Coma Scale score was 13 on admission. Her vital signs were as follows: blood pressure, 80/50 mmHg; pulse rate, 128/min; pulse oximetry, 90%; and respiration rate, 26/min. Her laboratory tests revealed the following: pH, 7.13; bicarbonate level, 10.1 mmol/L; and serum lactate level, 10.2 mmol/L. Other blood test results were normal. CVVH (Prismaflex hemofiltration set M150) was started in the intensive care unit because hypotension and metabolic acidosis were persistent; oliguria was added despite fluid resuscitation and inotrope infusion. Hemofiltration was continued until the 32nd hour when blood pressure and blood gas levels returned to normal. She was discharged healthy on the 4th day of hospitalization. Conclusion: We suggest the utilization of CVVH in the early stages of AP poisoning before the development of multiple organ failure because AP causes metabolic acidosis and hypotension resistant to medical treatment

Vitamin D levels in Cukurova Region

WOS: 000406284600016Purpose: The aim of ths study was to evaluate the increase in the request of plasma 25-hydroxy vitamin D level assay tests in Balcali Hospital of the Cukurova University during last 13 years and levels of 25-hydroxy vitamin D to determine the frequency of deficiency among the regional adult population admitting this hospital. Material and Methods: This study was performed by using pre-recorded electronic files and laboratory results of patients admitted to Balcali Hospital of the Cukurova University between 2003 and 2015. The number of 25-hydroxy vitamin D tests assayed of all ages between 20032015 and the diagnoses, age, gender, sampling, request, acceptance, confirmation times of tests, plasma 25-hydroxy vitamin D were evaluated. Results: The number of 25-hydroxy vitamin D tests assayed in the last 13 years was 77,569. When compared between years 2003-2013, number of 25-hydroxy vitamin D tests was increased 6785%. Mean plasma 25-hydroxy vitamin D levels were found to be higher in men (52.95 +/- 0.92 nmol/L) than women (48.42 +/- 0.54 nmol/L) (p<0.001). Among 6,198 patients included, 24.65% had 25-hydroxy vitamin D insufficiency and 35.95% had 25-hydroxy vitamin D deficiency. Only 15.62% of patients had optimal 25-hydroxy vitamin D levels. Conclusion: Although it is an extremely sunny environment, vitamin D insufficiency is a common and public health problem in Cukurova region. Many diseases may be prevented by education of how to benefit from sunrays and dietery supplements of vitamin D in risky population

Long term effect of general and regional anesthesia on bone turnover markers and fracture healing in adult patients

WOS: 000480626400030Purpose: Bone metabolism can be monitored quantitatively by measuring bone turnover markers in serum and/or urine. We aimed to investigate long-term effect of the type of the anesthesia on bone turnover markers and fracture healing. Materials and Methods: Thirty patients with American Society of Anesthesiologist physical status I-II whom were aged 40-70 years, scheduled for hip fracture were recruited. Patients were divided into the two groups as general anesthesia and regional anesthesia. Only morphine and tramadol were used for postoperative analgesia till the 12th weeks. Serum bone-specific alkaline phosphatase, osteocalcine, beta-C terminal telopeptide and urine beta-C terminal telopeptide levels were measured at preoperative, 4th week and 12th week of fracture. Results: A total of 25 patients were eligible for the study. There were no statistically significant between groups for values of bone turnover markers at the time point of preoperative, 4th and 12th weeks. With using linear regression analysis, serum beta-CTX levels at 12th week can be predict by 4th weeks beta-CTX levels (R2: 0.944) and urine beta-CTX levels at 12th week can be predict by first week level. Conclusions: This pilot study showed that both general and regional anesthesia has similar effect on bone turnover markers and fracture healing.Cukurova University Department of Scientific Research ProjectsCukurova University [4985]This study is supported by Cukurova University Department of Scientific Research Projects, Project ID: 4985, Approval Date: November 24, 2015

ACE gene polymorphism in children with Henoch-Schonlein purpura

43rd ERA-EDTA Congress -- JUL 15-18, 2006 -- Glasgow, SCOTLANDWOS: 000239919000213…ERA, EDT