The case of restricted locatives

International audienceThis paper examines the cross-linguistic phenomenon of locative case restricted to a closed class of items (L-nouns). Starting with Latin, I suggest that the restriction is semantic in nature: L-nouns denote in the spatial domain and hence can be used as locatives without further material. I show how the independently motivated hypothesis that directional PPs consist of two layers, Path and Place, explains the directional uses of L-nouns and the cases that are assigned then, and locate the source of the locative case itself in p 0 , for which I then provide a clear semantic contribution: a type-shift from the domain of loci to the object domain. I then examine cross-linguistic restrictions on the use of locative case and show that the patterns observed can be accounted for on the same assumptions

Ablaut and transitive softening in the Russian verb

Transitive softening in Russian is a type of consonant mutation resulting from an underlying [CjV] cluster. There exist two closed classes of verbs where it occurs in the present tense in the absence of a clear source for a glide: five verbs with the thematic suffix ‑o‑, which can be illustrated by the verb kolótʲ ‘to stab’, and some 100 verbs with the thematic suffix ‑a‑, which can be illustrated by the verb pisátʲ ‘to write’. To explain how [o] and [a] end up as glides, I propose that the vowels in question change into their front counterparts as a result of the same process as that responsible for the stem ablaut in the verb molótʲ ‘to grind’ (1sg: melʲú). I argue that the hypothesis that ablaut can apply to thematic vowels as well as to stems makes it possible to account for another Russian verb exhibiting an unexpected behavior in the present tense (revétʲ ‘to bellow’). Since the latter part of the argument introduces ablauts involving more than one feature, the remainder of the paper is dedicated to the discussion of how multiple feature changes should be formalized

Hiwi Mediated Tumorigenesis Is Associated with DNA Hypermethylation

Expression of Piwi proteins is confined to early development and stem cells during which they suppress transposon migration via DNA methylation to ensure genomic stability. Piwi's genomic protective function conflicts with reports that its human ortholog, Hiwi, is expressed in numerous cancers and prognosticates shorter survival. However, the role of Hiwi in tumorigenesis has not been examined. Here we demonstrate that (1) over-expressing Hiwi in sarcoma precursors inhibits their differentiation in vitro and generates sarcomas in vivo; (2) transgenic mice expressing Hiwi (mesodermally restricted) develop sarcomas; and (3) inducible down-regulation of Hiwi in human sarcomas inhibits growth and re-establishes differentiation. Our data indicates that Hiwi is directly tumorigenic and Hiwi-expressing cancers may be addicted to Hiwi expression. We further show that Hiwi associated DNA methylation and cyclin-dependent kinase inhibitor (CDKI) silencing is reversible along with Hiwi-induced tumorigenesis, via DNA-methyltransferase inhibitors. Our studies reveal for the first time not only a novel oncogenic role for Hiwi as a driver of tumorigenesis, but also suggest that the use of epigenetic agents may be clinically beneficial for treatment of tumors that express Hiwi. Additionally, our data showing that Hiwi-associated DNA hyper-methylation with subsequent genetic and epigenetic changes favoring a tumorigenic state reconciles the conundrum of how Hiwi may act appropriately to promote genomic integrity during early development (via transposon silencing) and inappropriately in adult tissues with subsequent tumorigenesis

Les adjectifs – Une introduction

Cet article représente une brève introduction au domaine des adjectifs, leur syntaxe, sémantique et morphologie, ainsi qu’à la typologie des adjectifs. Il discute quelques-uns des thèmes les plus souvent abordés de ce domaine, tels que l’emploi épithète et l’emploi prédicatif des adjectifs; la sémantique et la syntaxe de la dépendance contextuelle y compris la scalarité; la structure argumentale des adjectifs; la syntaxe du syntagme adjectival et son comportement à l’intérieur et à l’extérieur du syntagme nominal; l’existence d’une classe des adjectifs, distincte des noms et des verbes, et les propriétés des adjectifs à travers les langues; et les questions de la morphologie adjectivale (l’accord, les affixes dérivationnels, etc.)

Movement of degree/degree of movement

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2002.Includes bibliographical references (leaves 190-196).In this project we examine the DP-internal behavior of degree operators contained in attributive extended APs, specifically degree fronting (so sunny a day) and degree right extraposition (a day sunny enough). We argue that both processes have to do with the scope of the degree operator, namely, that degree fronting is a diagnostic of clausal scope of the degree operator, while right extraposition is overt QR to the DP-internal landing site where a quantifier can be interpreted. We first show that pre-determiner APs in Germanic languages (so sunny a day) are moved to [Spec, NumP] only if they contain a degree operator, i.e. an element that cannot be interpreted in situ. We will then show that the appearance of the adjectival projection in that position is due to pied-piping, and that different degree operators behave differently with respect to how much material is moved overtly (pied-piping). We then turn to right extraposition. We will show that it can be differentiated from other cases traditionally denoted by the same term (e.g. a professor proud of her children). On the other hand, it has certain properties permitting to assimilate it to DP-extraposition to the right periphery of the vP (Heavy NP Shift) - it has new information status and permits stranding of the argument of the degree operator (a more interesting problem than this). These and similar factors suggest that right extraposition of degree-containing extended APs is overt QR of the degree operator accompanied by more or less pied-piping. The overall picture seems to be that QR an overt movement processes examined for clausal projections exist in nominal projections as well and have similar properties.by Ora Mitchell Matushansky.Ph.D

A programme of additional training for participation in the competition worldskills international jewelry

The article presents a comparative analysis of The WorldSkills specification standards for jewelry and professional competencies of the Federal state educational standard of secondary vocational education in the field of "arts and crafts"Проводится сравнительный анализ стандартов спецификации WorldSkills по ювелирному делу и профессиональных компетенций, обозначенных в Федеральном государственном образовательном стандарте среднего профессионального образования в сфере декоративно-прикладного искусства и народных промысло

Russell-names: an introduction to Millian descriptivism

This essay studies the semantic properties of what I call Russell-names. Russell-names bear intimate semantic relations with descriptive conditions, in consonance with the main tenets of descriptivism. Yet, they are endowed with the semantic properties attributed to ordinary proper names by Millianism: they are rigid and non-indexical devices of direct reference. This is not an essay in natural language semantics, and remains deliberately neutral with respect to the question whether any among the expressions we ordinarily classify as proper names behave as Russell-names. Its aim is rather that of casting a new light on the traditional debate about descriptivism on the one hand, and, on the other, what is commonly understood as a radically anti-descriptivist approach. From the viewpoint of descriptivism, the conceivability of Russell-names provides welcome relief from the pressure exerted by considerations at odds with a flaccid and/or indexical treatment of proper names. Conversely, from a Millian standpoint, the conceivability of Russell-names indicates that the Millian stance, far from providing a meagre picture of names as ‘mere tags’, is at least in principle consistent with the recognition of their semantic bonds with richer descriptive material. The Appendix provides a formal treatment of Russell-names within a model theoretic semantics for indexical intensional languages, developed within an original ‘double-context’ framework

The descriptive content of names as predicate modifiers

In this paper I argue that descriptive content associated with a proper name can serve as a truth-conditionally relevant adjunct and be an additional contribution of the name to the truth-conditions. Definite descriptions the so-and-so associated by speakers with a proper name can be used as qualifying prepositional phrases as so-and-so, so sentences containing a proper name NN is doing something could be understood as NN is doing something as NN (which means as so-and-so). Used as an adjunct, the descriptive content of a proper name expresses the additional circumstances of an action (a manner, reason, goal, time or purpose) and constitute a part of a predicate. I argue that qualifying prepositional phrases should be analyzed as predicate modifiers and propose a formal representation of modified predicates. The additional truth-conditional relevance of the descriptive content of a proper name helps to explain the phenomenon of the substitution failure of coreferential names in simple sentences