Neurophysiology

Contains reports on seven research projects.Bell Telephone Laboratories, IncorporatedNational Institutes of HealthTeagle Foundation, IncorporatedUnited States Air Force (WADD Contract AF33(616)-7783

Towards Autopoietic Computing

A key challenge in modern computing is to develop systems that address complex, dynamic problems in a scalable and efficient way, because the increasing complexity of software makes designing and maintaining efficient and flexible systems increasingly difficult. Biological systems are thought to possess robust, scalable processing paradigms that can automatically manage complex, dynamic problem spaces, possessing several properties that may be useful in computer systems. The biological properties of self-organisation, self-replication, self-management, and scalability are addressed in an interesting way by autopoiesis, a descriptive theory of the cell founded on the concept of a system's circular organisation to define its boundary with its environment. In this paper, therefore, we review the main concepts of autopoiesis and then discuss how they could be related to fundamental concepts and theories of computation. The paper is conceptual in nature and the emphasis is on the review of other people's work in this area as part of a longer-term strategy to develop a formal theory of autopoietic computing.Comment: 10 Pages, 3 figure

Self-organisation and psychotherapy

Neste artigo, resultado de uma pesquisa de tipo qualitativo, hermenêutico e documental, procuramos mostrar como as Ciências Cognitivas, desde a sua constituição, têm contribuído para a compreensão do ser humano. Fazemos referência às visões mais racionalistas da mente, que a entendem semelhante a um sistema computacional, até à visão menos (não) racionalista que lhe confere valor cognitivo, envolta em emoções e afetos, que numa visão mais construtivista – ou pós-racionalista – se diria que traduz significados, traduz uma vivência ou uma história narrativa (e) pessoal. Assim, apresentamos o modelo de terapia cognitiva pós-racionalista de Vittorio Guidano, refletindo sobre os fundamentos epistemológicos do Movimento da Auto-organização (MAO), nos quais ele se fundamenta. Descrevemos sumariamente os alicerces epistemológicos do MAO, os quais garantem a este modelo uma dimensão holista e explicativa do processo de construção da identidade humana, que pode ser descrita como processo de conhecimento, capaz de vivenciar e ao mesmo tempo perceber e avaliar a sua própria experiência (autoconsciência). O ser humano age na intersubjetividade, num mundo pluralista, com os seus congéneres, partilhando experiências e interpretando ações (complexificando-se através desses acoplamentos). Pretendemos, também, ilustrar que a matriz de funcionamento interno de cada ser humano, a qual lhe permite ordenar essa múltipla e facetada realidade, assim como formar/construir/ordenar significados pessoais, é o vínculo emotivo-afetivo.In this paper, which is the result of a qualitative, hermeneutical and documental research, we intend to show how the Cognitive Sciences, since their beginning, have contributed to the understanding of human beings. We refer to the rationalistic understanding of the mind (the mind is like a computer system), and also to the non-rationalistic understanding, which attributes to the mind a cognitive value, immersed in emotions and affections. In addition, according to a constructivist or post-rationalistic understanding, the mind translates meanings, an experience or a personal narrative story. Thus, we present the model of post-rationalistic cognitive therapy of Vittorio Guidano, reflecting on the epistemological foundations of the Self-Organization Movement, on which it is based. We describe briefly the epistemological principles of the Self-Organization Movement, which give to this model a holistic and explanatory dimension of the process of construction of human identity. This identity can be described as the human beings’ process of self-knowledge, as we are capable of experiencing and at the same time perceiving and evaluating, our own experiences (self-consciousness). The human being acts on intersubjectivity, in a pluralistic world with his peers, sharing experiences and interpreting actions. We also want to illustrate that the matrix of inner functioning of every human being, which allows us to sort this multi-faceted reality in a single personal order, is the emotional bond.(undefined

Towards a typology of inter-municipal cooperation in emerging metropolitan regions. A case study in the solid waste management sector in Ecuador

Inter-municipal cooperation (IMC) is a widely studied governance solution. Most literature defines IMC as a particular service delivery arrangement. However, we argue that IMC manifests itself in several forms and thus a broader definition is necessary. To explore this, we conducted a case study in the solid waste management sector of the emerging metropolitan region in Cuenca-Azogues, Ecuador. Emerging metropolitan regions are particularly suitable for analysing IMC, and so far, there are few studies on IMC in Latin America. Based on the discrepancy between previous studies and the results of our research, we develop a new definition and a new typology of IMC, which can be related to multiple service delivery arrangements

Biological and methodological factors affecting VO2max response variability to endurance training and the influence of exercise intensity prescription

© 2021 The Authors. Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution License. https://creativecommons.org/licenses/by/4.0/Changes in cardiorespiratory fitness (CRF) in response to endurance training (ET) exhibit large variations, possibly due to a multitude of biological and methodological factors. It is acknowledged that ~20% of individuals may not achieve meaningful increases in CRF in response to ET. Genetics, the most potent biological contributor, has been shown to explain ~50% of response variability, whilst age, sex, and baseline CRF appear to explain a smaller proportion. Methodological factors represent the characteristics of the ET itself including the type, volume, and intensity of exercise, as well as the method used to prescribe and control exercise intensity. Notably, methodological factors are modifiable and, upon manipulation, alter response rates to ET, eliciting increases in CRF regardless of an individual’s biological predisposition. Particularly, prescribing exercise intensity relative to a physiological threshold (e.g. ventilatory threshold) is shown to increase CRF response rates compared to when intensity is anchored relative to a maximum physiological value (e.g. maximum heart rate). It is, however, uncertain whether the increased response rates are primarily attributable to reduced response variability, greater mean changes in CRF, or both. Future research is warranted to elucidate whether more homogenous chronic adaptations manifest over time among individuals, as a result of exposure to more homogenous exercise stimuli elicited by threshold-based practices.Peer reviewe

Neurophysiology

Contains research objectives and reports on three research projects.U. S. Air Force Office of Scientific Research under Contract AF49(638)-398National Institutes of HealthTeagle Foundation, IncorporatedBell Telephone Laboratories, Incorporate

Neurophysiology

Contains research objectives and reports on nine research projects.The Teagle Foundation, Inc.U.S. Air Force (Aeronautical Systems Division) under Contract AF33(616)-7783Bell Telephone Laboratories, Inc.National Institutes of Health [Grant M-4235-(C1)]National Institutes of Health (Grant B-1865-(C3))National Institutes of Health (Grant MP-4737)National Institutes of Health (Grant B-2480(C1)