6 research outputs found

    Self-guardianship at automated teller machines

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    Automated teller machines (ATMs) are central to the functioning of developed economies, but by their very nature operate without human supervision, making them vulnerable to criminal abuse. This study sought to understand how customers protect themselves from theft while using ATMs. Observations of and surveys with ATM customers were used to identify how individuals protect themselves from theft of cash, card or personal details while using an ATM. The most common self-guardianship measure was to use only ATMs believed to be safe. The majority of customers did not cover the ATM keypad while entering their personal identification number (PIN), despite long-running publicity campaigns encouraging this behaviour. This suggests that self guardianship is important at ATMs, but many customers fail to take even basic measures to protect themselves, their money and their bank details from theft. Banks and crime-prevention practitioners should do more to facilitate and encourage self guardianship at ATMs

    A bioinformatics screen reveals hox and chromatin remodeling factors at the Drosophila histone locus

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    Abstract Background Cells orchestrate histone biogenesis with strict temporal and quantitative control. To efficiently regulate histone biogenesis, the repetitive Drosophila melanogaster replication-dependent histone genes are arrayed and clustered at a single locus. Regulatory factors concentrate in a nuclear body known as the histone locus body (HLB), which forms around the locus. Historically, HLB factors are largely discovered by chance, and few are known to interact directly with DNA. It is therefore unclear how the histone genes are specifically targeted for unique and coordinated regulation. Results To expand the list of known HLB factors, we performed a candidate-based screen by mapping 30 publicly available ChIP datasets of 27 unique factors to the Drosophila histone gene array. We identified novel transcription factor candidates, including the Drosophila Hox proteins Ultrabithorax (Ubx), Abdominal-A (Abd-A), and Abdominal-B (Abd-B), suggesting a new pathway for these factors in influencing body plan morphogenesis. Additionally, we identified six other factors that target the histone gene array: JIL-1, hormone-like receptor 78 (Hr78), the long isoform of female sterile homeotic (1) (fs(1)h) as well as the general transcription factors TBP associated factor 1 (TAF-1), Transcription Factor IIB (TFIIB), and Transcription Factor IIF (TFIIF). Conclusions Our foundational screen provides several candidates for future studies into factors that may influence histone biogenesis. Further, our study emphasizes the powerful reservoir of publicly available datasets, which can be mined as a primary screening technique
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