7,296 research outputs found
Measuring Poverty in the Pacific
Measuring poverty in the Pacific is important to keep poor people on the policy agenda, to design effective policies and programs and to carry out rigorous evaluation so that we know what works and why. There are various definitions of poverty, ranging from a narrow focus on adequate calorie consumption through to broader concepts of capabilities. This paper takes a practical look at how to measure one conventional indicator of poverty: income (or consumption) poverty. In doing so, the paper highlights both the limitations of household datasets in the Pacific as well as opportunities to make better use of data for poverty analysis. Good progress is being made in improving the quality of household surveys, so the challenge now is to analyse these more fully to inform policies, program design and evaluation.aid
Beyond Paris: 11 innovations in aid effectiveness
The current framework for improving aid effectiveness, the 'Paris' agenda of harmonisation and alignment, has been found lacking. Alternatives are needed. This paper highlights some examples of recent innovations in the management and delivery of development aid. Drawing upon Barder (2009) and Howes (2011), the paper structures 11 innovations into three categories: improving the quality of the aid donor; improving the quality of the aid recipient; and improving how donors interact and the way aid is given. By examining these 11 innovations, the paper shows that aid agencies have the potential to adapt and evolve. The challenge for donors is to start selecting good ideas for implementation now and to never stop searching for new innovations to improve aid effectiveness.aid
Mobility Measurements Probe Conformational Changes in Membrane Proteins due to Tension
The function of membrane-embedded proteins such as ion channels depends
crucially on their conformation. We demonstrate how conformational changes in
asymmetric membrane proteins may be inferred from measurements of their
diffusion. Such proteins cause local deformations in the membrane, which induce
an extra hydrodynamic drag on the protein. Using membrane tension to control
the magnitude of the deformations and hence the drag, measurements of
diffusivity can be used to infer--- via an elastic model of the protein--- how
conformation is changed by tension. Motivated by recent experimental results
[Quemeneur et al., Proc. Natl. Acad. Sci. USA, 111 5083 (2014)] we focus on
KvAP, a voltage-gated potassium channel. The conformation of KvAP is found to
change considerably due to tension, with its `walls', where the protein meets
the membrane, undergoing significant angular strains. The torsional stiffness
is determined to be 26.8 kT at room temperature. This has implications for both
the structure and function of such proteins in the environment of a
tension-bearing membrane.Comment: Manuscript: 4 pages, 4 figures. Supplementary Material: 8 pages, 1
figur
VOSpace: a Prototype for Grid 2.0
As Grid 1.0 was characterized by distributed computation, so Grid 2.0 will be characterized by distributed data and the infrastructure needed to support and exploit it: the emerging success of Amazon S3 is already testimony to this. VOSpace is the IVOA interface standard for accessing distributed data. Although the base definition (VOSpace 1.0) only relates to flat, unconnected data stores, subsequent versions will add additional layers of functionality. In this paper, we consider how incorporating popular web concepts such as folksonomies (tagging), social networking, and data-spaces could lead to a much richer data environment than provided by a traditional collection of networked data stores
Investigation Into the Responses of Physcomitrella patens to Herbivory and the Influence of Light on the Production of Defense Compounds
Plant defense mechanisms are well studied in many agriculturally relevant crops such as corn and tomatoes. Though less studied, the more ancestral nonvascular plants may be able to provide insights into the origin and working of modern plant defense systems. In this study, the bryophyte Physcomitrella patens was researched and the role of the jasmonic acid pathway in response to herbivory was investigated. Additionally, the impact of light intensity on the efficacy of this pathway was to be determined. After exposing the moss to various chemical elicitors and mechanical wounding, the activity of proteins produced in the JA pathway was measured. In P. patens, no definitive conclusions could be drawn regarding the role of JA in the defense against herbivory. Due to a lack of results from the initial experiments, the light experiments were not performed
A Hip Strengthening Protocol For A Patient Following Achilles Repair: A Case Report
Background and Purpose: The Achilles tendon is the strongest, yet most frequently ruptured, tendon in the body. Hip strength has been associated with various lower extremity (LE) conditions. However, there is a lack of literature regarding hip strengthening and its impact on Achilles injuries. Therefore, the purpose of this case report was to describe the rehabilitation of a patient following a left Achilles tendon repair utilizing a comprehensive hip strengthening protocol. Case Description: The patient was a 32-year-old female who ruptured her Achilles playing tennis. She underwent surgical repair three weeks later and was immobilized and non-weightbearing for a total of seven weeks. Manual muscle testing (MMT), range of motion (ROM), the Lower Extremity Functional Scale (LEFS), Foot and Ankle Disability Index (FADI), and the Achilles tendon Total Rupture Score (ATRS) were used to evaluate progress. Interventions included hip and ankle strengthening, ROM, stretching, manual therapy, balance training, and gait training. Outcomes: The patient attended 18 visits over 11 weeks. Left ankle plantarflexion strength improved from +3/5 to -5/5. Left hip abduction improved from 4/5 to -5/5 and left hip extension improved from +4/5 to -5/5. Left ankle dorsiflexion AROM improved from -20° to 10°. LEFS scores improved from 28/80 to 57/80. FADI scores improved from 37% to 91.3% and ATRS scores improved from 52/100 to 32/100. Discussion: The patient made improvements consistent with existing literature. Utilizing a hip strengthening protocol following Achilles repair may be beneficial, but the full magnitude of the effect of hip strengthening cannot be determined. Future research should focus on the effect of hip strengthening following Achilles repair, as well as the impact of hip weakness on Achilles injuries
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