817 research outputs found
I2PA, U-prove, and Idemix: An Evaluation of Memory Usage and Computing Time Efficiency in an IoT Context
The Internet of Things (IoT), in spite of its innumerable advantages, brings
many challenges namely issues about users' privacy preservation and constraints
about lightweight cryptography. Lightweight cryptography is of capital
importance since IoT devices are qualified to be resource-constrained. To
address these challenges, several Attribute-Based Credentials (ABC) schemes
have been designed including I2PA, U-prove, and Idemix. Even though these
schemes have very strong cryptographic bases, their performance in
resource-constrained devices is a question that deserves special attention.
This paper aims to conduct a performance evaluation of these schemes on
issuance and verification protocols regarding memory usage and computing time.
Recorded results show that both I2PA and U-prove present very interesting
results regarding memory usage and computing time while Idemix presents very
low performance with regard to computing time
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Wetting behaviour and reactivity between liquid Gd and ZrO2 substrate
The wetting behavior and reactivity between molten pure Gd and polycrystalline 3YSZ substrate (ZrO2 stabilized with 3 wt% of Y2O3)were experimentally determined by a sessile drop method using a classical contact heating coupled with drop pushing procedure. The test was performed under an inert flowing gas atmosphere (Ar) at two temperatures of 1362°C and 1412°C. Immediately after melting (Tm=1341°C), liquid Gd did not wet the substrate forming a contact angle of θ=141°. The non-wetting to wetting transition (θ < 90°) took place after about 110 seconds of interaction and was accompanied by a sudden decrease in the contact angle value to 67°. Further heating of the couple to 1412 °C did not affect wetting (θ=67°±1°). The solidified Gd/3YSZ couple was studied by means of optical microscopy and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy. Structural investigations revealed that the wettability in the Gd/3YSZ system is of a reactive nature associated with the formation of a continuous layer of a wettable reaction product Gd2Zr2O7
Unresolved Issues in RNA Therapeutics in Vascular Diseases With a Focus on Aneurysm Disease
New technologies have greatly shaped the scientific and medical landscape within the
last years. The unprecedented expansion of data and information on RNA biology
has led to the discovery of new RNA classes with unique functions and unexpected
modifications. Today, the biggest challenge is to transfer the large number of findings
in basic RNA biology into corresponding clinical RNA-based therapeutics. Lately, this
research begins to yield positive outcomes. RNA drugs advance to the final phases
of clinical trials or even receive FDA approval. Furthermore, the introduction of the
RNA-guided gene-editing technology CRISPR and advances in the delivery ofmessenger
RNAs have triggered a major progression in the field of RNA-therapeutics. Especially
short interfering RNAs and antisense oligonucleotides are promising examples for novel
categories of therapeutics. However, several issues need to be addressed including
intracellular delivery, toxicity, and immune responses before utilizing RNAs in a clinical
setting. In this review, we provide an overview on opportunities and challenges for clinical
translation of RNA-based therapeutics, with an emphasis on advances in novel delivery
technologies and abdominal aortic aneurysm disease where non-coding RNAs have
been shown to play a crucial regulatory role
Structural behavior of Pd40Cu30Ni10P20 bulk metallic glass below and above the glass transition
Various Sizes of Sliding Event Bursts in the Plastic Flow of Metallic Glasses Based on a Spatiotemporal Dynamic Model
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Assessing middle school students` understanding of science relationships and processes: Year 2 - instrument validation. Final report
Our overall purpose for this multi-year project was to develop an alternative assessment format measuring rural middle school students understanding of science concepts and processes and the interrelationships among them. This kind of understanding is called structural knowledge. We had 3 major interrelated goals: (1) Synthesize the existing literature and critically evaluate the actual and potential use of measures of structural knowledge in science education. (2) Develop a structural knowledge alternative assessment format. (3) Examine the validity of our structural knowledge format. We accomplished the first two goals during year 1. The structural knowledge assessment we identified and developed further was a select-and-fill-in concept map format. The goal for our year 2 work was to begin to validate this assessment approach. This final report summarizes our year 2 work
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Assessing middle school students` understanding of science relationships and processes. Final report
Our overall goal for this multi-year project is to develop and validate an alternative assessment format that effectively measures middle school students understanding of the relationships among selected science concepts and processes. In this project, we collaborate with the staff of the Los Alamos National Laboratory`s TOPS Program and the Programs participating teachers and their students. We also work with selected middle school science teachers from the TOPS program at Sandia National Laboratories. Our goal for this past year was to develop and field test informally a variety of potential measurement formats. This work has allowed us to identify formats to test during the validation phase of the project which will occur during the second year
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Crystallization of Fe82Si2B16 and Fe82Si4B14 metallic glasses upon isothermal and non-isothermal annealing
Crystallization of Fe82Si2B16 and Fe82Si4B14 metallic glasses upon heat treatment has been studied. The amorphous ribbons have been isothermally annealed at different temperatures (673, 693, 733 and 743 K) and for various times (from 15 min to 78 hours). Phase compositions and the sequence of their appearance in dependence on the annealing temperature and time have been established
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