Development of a separable search-and-rescue robot composed of a mobile robot and a snake robot

In this study, we propose a new robot system consisting of a mobile robot and a snake robot. The system works not only as a mobile manipulator but also as a multi-agent system by using the snake robot's ability to separate from the mobile robot. Initially, the snake robot is mounted on the mobile robot in the carrying mode. When an operator uses the snake robot as a manipulator, the robot changes to the manipulator mode. The operator can detach the snake robot from the mobile robot and command the snake robot to conduct lateral rolling motions. In this paper, we present the details of our robot and its performance in the World Robot Summit

Acute exacerbation of pleuroparenchymal fibroelastosis with lower lobe usual interstitial pneumonia: An autopsy case

An 87-year-old man presented with dyspnea. Computed tomography revealed progressive subpleural consolidation in the apex, reticular shadows in the lower lobes, and bilateral ground glass opacifications. He died of respiratory failure on day 3. The post-mortem examination showed exudative stage diffuse alveolar damage and pulmonary edema. Intraalveolar collagenous fibrosis and subpleural elastosis were observed in the upper lobes, accompanied by interlobular septal and pleural thickening and lung architecture remodeling in the lower lobes. He was diagnosed with acute exacerbation of pleuroparenchymal fibroelastosis with lower lobe usual interstitial pneumonia, which can be fatal

Pairwise Engineering of Tandemly Aligned Self-Splicing Group I Introns for Analysis and Control of Their Alternative Splicing

Alternative splicing is an important mechanism in the process of eukaryotic nuclear mRNA precursors producing multiple protein products from a single gene. Although group I self-splicing introns usually perform regular splicing, limited examples of alternative splicing have also been reported. The exon-skipping type of splicing has been observed in genes containing two group I introns. To characterize splicing patterns (exon-skipping/exon-inclusion) of tandemly aligned group I introns, we constructed a reporter gene containing two Tetrahymena introns flanking a short exon. To control splicing patterns, we engineered the two introns in a pairwise manner to design pairs of introns that selectively perform either exon-skipping or exon-inclusion splicing. Through pairwise engineering and biochemical characterization, the structural elements important for the induction of exon-skipping splicing were elucidated

Simulations of systematic effects arising from cosmic rays in the LiteBIRD space telescope, and effects on the measurements of CMB B-modes

International audienceSystematic effects arising from cosmic rays have been shown to be a significant threat to space telescopes using high-sensitivity bolometers. The LiteBIRD space mission aims to measure the polarised Cosmic Microwave Background with unprecedented sensitivity, but its positioning in space will also render it susceptible to cosmic ray effects. We present an end-to-end simulator for evaluating the expected scale of cosmic ray effects on the LiteBIRD space mission, which we demonstrate on a subset of detectors on the 166 GHz band of the Low Frequency Telescope. The simulator couples the expected proton flux at L2 with a model of the thermal response of the LFT focal plane and the electrothermal response of its superconducting detectors, producing time-ordered data which is projected into simulated sky maps and subsequent angular power spectra