106 research outputs found

    Near-optimal stochastic MIMO signal detection with a mixture of t-distribution prior

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    Multiple-input multiple-output (MIMO) systems will play a crucial role in future wireless communication, but improving their signal detection performance to increase transmission efficiency remains a challenge. To address this issue, we propose extending the discrete signal detection problem in MIMO systems to a continuous one and applying the Hamiltonian Monte Carlo method, an efficient Markov chain Monte Carlo algorithm. In our previous studies, we have used a mixture of normal distributions for the prior distribution. In this study, we propose using a mixture of t-distributions, which further improves detection performance. Based on our theoretical analysis and computer simulations, the proposed method can achieve near-optimal signal detection with polynomial computational complexity. This high-performance and practical MIMO signal detection could contribute to the development of the 6th-generation mobile network.Comment: to be published in the 2023 IEEE Global Communications Conference (GLOBECOM

    Etiler'de Locanda

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    Taha Toros Arşivi, Dosya No: 112-Lokantalarİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

    Effect of streptococcal preparation (picibanil) on the postoperative rise in serum alanine aminotransferase activity in patients with urogenital cancer.

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    The effect of Picibanil, a streptococcal agent, on the development of liver injury after operations for urogenital cancer was studied retrospectively in the light of serum alanine aminotransferase (ALT) activity. The series comprised 32 cases receiving Picibanil and 33 controls with otherwise comparable clinical backgrounds. Picibanil reduced the incidence of postoperative ALT rise over 50 U/l within 6 weeks but increased it thereafter. The increase in ALT activity after 6 weeks was relatively small and was seen more often in patients given blood transfusions. It was interpreted as retardation and suppression of ALT rise and as being related to the induction of interferon or to immunopotentiation. Other antihepatotoxic effects of Picibanil, due to its antioxidant activity, for example, may also account for the prevention of the early postoperative rise in ALT activity.</p

    imary testicular plasmacytoma: a case report.

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    &#60;P&#62;A 73-year-old man with a left testicular tumor is presented. Orchiectomy was performed and the tumor was diagnosed as a plasmacytoma. There has been no bone lesion or immunoglobulin abnormality during a follow-up period more than one year. For several reasons, the tumor was regarded as a primary plasmacytoma of the testicle. The literature concerning testicular plasmacytoma is reviewed briefly.</p

    The effects of intravesical instillation of Thio-Tepa on the recurrence rate of bladder tumors.

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    Seventy-eight patients were treated with intravesical instillation of Thio-Tepa in an attempt to prevent postoperative recurrences of bladder tumors. Fifty-six patients who were given no preventive treatment against recurrences were taken as the control group. The patients in this series presented at the Okayama University Hospital between 1961 and 1976 and only the first recurrence after the primary operation was taken into consideration. There was no significant difference in the recurrence rates of the control and instillation groups

    Phosphorylated Platelet-Derived Growth Factor Receptor-Positive Cells With Anti-apoptotic Properties Accumulate in the Synovium of Patients With Rheumatoid Arthritis

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    Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and characterized by chronic polyarthritis that destroys bone and cartilage. Fibroblast-like synoviocytes (FLSs) in the synovium of patients with RA can promote cartilage and bone destruction by producing proteins such as matrix metalloproteinases and receptor activator of NF-κB ligand, thereby representing an important therapeutic target for RA. FLSs have several phenotypes depending on which cell surface proteins and adhesion factors are expressed. Identifying the cellular functions associated with different phenotypes and methods of controlling them are considered essential for developing therapeutic strategies for RA. In this study, synovial tissue was collected from patients with RA and control subjects who required surgery due to ligament injury or fracture. Immunohistological analysis was used to investigate the rates of positivity for phosphorylated platelet-derived growth factor receptor-αβ (pPDGFRαβ) and cadherin-11 (CDH11) expression, and apoptosis-related markers were assessed for each cell phenotype. Next, FLSs were isolated in vitro and stimulated with tumor necrosis factor-α (TNF-α) in addition to a combination of PDGF and transforming growth factor (2GF) to investigate pPDGFRαβ and CDH11 expression and the effects of the inhibition of TNF and cyclin-dependent kinase (CDK) 4/6 on FLSs. Immunohistological analysis showed a large percentage of pPDGFRαβ+CDH11– cells in the sub-lining layer (SL) of patients with RA. These cells exhibited increased B-cell lymphoma-2 expression, reduced TNF receptor-1 expression, resistance to cell death, and abnormal proliferation, suggesting a tendency to accumulate in the synovium. Further, in vitro 2GF stimulation of FLSs lowered, whereas 2GF + TNF stimulation increased the pPDGFRαβ/CDH11 ratio. Hypothesizing that FLSs stimulated with 2GF + TNF would accumulate in vivo in RA, we determined the therapeutic effects of TNF and CDK4/6 inhibitors. The TNF inhibitor lowered the pPDGFRαβ/CDH11 ratio, whereas the CDK4/6 inhibitor suppressed cell proliferation. However, a synergistic effect was not observed by combining both the drugs. We observed an increase in pPDGFRαβ+CDH11– cells in the SL of the RA synovium and accumulation of these cells in the synovium. We found that the TNF inhibitor suppressed FLS activity and the CDK4/6 inhibitor reduced cell proliferation

    RELATIONSHIP BETWEEN PROGRESSION OF AORTIC STENOSIS AND INFLAMMATORY CHANGE IN AORTIC VALVE IN HEMODIALYSIS PATIENTS

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    The entire manuscript is available for download as a single PDF file. Higher-resolution images are unavailable. For assistance, please contact [email protected]. Fieldwork Team: Philippe Beaujard (Director of Research, French National Centre for Scientific Research). Technical Team: Dr. Vika Zafrin (Digital Scholarship Librarian, BU Libraries), Eleni Castro (OpenBU and Electronic Theses & Dissertations Librarian, BU Libraries), Dr. Fallou Ngom (Director of the African Studies Center), Dr. Peter Quella (Assistant Director, African Studies Center), Mustapha Hashim Kurfi (PhD Candidate, Department of Political Science), and Zachary Gersten (Research Assistant, African Studies Center). This collection of Malagasy Ajami materials is copied as part of the African Studies Center’s African Ajami Library. This project is partly funded by the BU African Studies Center. We thank Dr. Tim Longman, past Director of the African Studies Center, and the entire African Studies team for their support. For Inquiries: Please contact Professor Fallou Ngom ([email protected]).The material is the second part of the sixth of eleven texts (the fourth text and the second and third parts of the eleventh were not digitized) owned by Iaban’i Totôry, a diviner-healer (called ombiasy in Malagasy). Iaban’i Totôry belonged to the Anakara Clan and lived in a village called Vatomasina in the Antemoro region (in the valley of the Matatàña River). He was known to be the grandson of a famous religious chief in his village, and was close with the French colonial administration in his region, with whom he also shared the material. The original author of the material is unknown. The material was photographed between 1983 and 1990. The pages were made out of a local plant called harandrànto in Malagasy, likely of the genus Afzelia. The material was bound in zebu skin and sinew. While the exact content of material is unknown, it is believed to contain guidance for charms, divination, and healing through prayers, geomancy, and astrology
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