6 research outputs found

    電場が温水処理に伴うSiO2-TiO2系ゲルコーティング膜のチタニア微結晶生成に及ぼす影響

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    Sol-gel derived SiO2-TiO2 coatings on indium tin oxide (ITO)-coated glass substrates were treated with hot water at 90°C under electric field aiming at the control of morphology and crystalline phase of the titania precipitates. The shape of the precipitates on 75SiO2•25TiO2 (mol%) coating at the negative electrode changed from granular to ramiform by applying an electric field to the substrates during the treatment, whereas such changes in the shape of titania nanocrystals with the electric field were not observed at the positive electrode. The granular and ramiform precipitates were identified as anatase (TiO2) and hydrated titania (n(TiO2)•mH2O), respectively. The ramiform shape of the titania precipitates became significant with increasing the applied voltage, while the coatings gradually dark-colored due to the reduction of Ti4+ to Ti3+

    Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic fatty liver disease

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    Objective: The aim of this study was to examine the association between ectopic fat and organ-specific insulin resistance (IR) in insulin-target organs in patients with nonalcoholic fatty liver disease (NAFLD). Methods: Organ-specific IR in the liver (hepatic glucose production (HGP)6fasting plasma insulin (FPI) and suppression of HGP by insulin [%HGP]), skeletal muscle (insulin-stimulated glucose disposal [Rd]), and adipose tissue (suppression of FFA by insulin [%FFA]) was measured in 69 patients with NAFLD using a euglycemic hyperinsulinemic clamp with tracer infusion ([6,6-2H 2]glucose). Liver fat, intramyocellular lipid (IMCL), and body composition were measured by liver biopsy, proton magnetic resonance spectroscopy, and bioelectrical impedance analysis, respectively. Results: HGPxFPI was significantly correlated with Rd (r = -0.57, P<0.001), %HGP with %FFA (r = 0.38, P<0.01), and Rd with %FFA (r = 0.27, P<0.05). Liver steatosis score was negatively associated with Rd (r = -0.47, P<0.001) as well as with HGPxFPI ( r = 0.43, P<0.001). Similarly, intrahepatic lipid was negatively associated with Rd (r = -0.32, P<0.05). IMCL was not associated with Rd (r = -0.16, P = 0.26). Fat mass and its percentage were associated with HGPxFPI (r = 0.50, P<0.001; r = 0.48, P<0.001, respectively) and Rd (r = -0.59, P<0.001; r = -0.52, P<0.001, respectively), but not with %FFA (r = -0.21, P = 0.10; r = -0.001, P = 0.99, respectively). Conclusion: Unexpectedly, fat accumulation in the skeletal muscle and adipose tissue was not associated with organ-specific IR. Instead, liver fat was associated not only with hepatic IR but also with skeletal muscle IR, suggesting a central role of fatty liver in systemic IR and that a network exists between liver and skeletal muscle. © 2014 Kato et al

    A Σp\Sigma p scattering Experiment at J-PARC and the Analysis Status

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    International audienceJ-PARC E40 aims to measure the differential cross sections of the Σ^±p elastic scatterings and the Σ^−p → Λn conversion. A clear peak of Σ^− was observed in a missing mass spectrum of the π^−p → K^+X reaction and recoil protons from the πp elastic scattering were successfully observed in the data taken in the summer 2018. The rest of data taking is coming in the spring 2019
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