Becoming Intergenerational in Birth Cohorts: kinship and the remaking of participation

In recent years birth cohorts have become an invaluable context, resource, tool and ‘technology’ of an emerging terrain of biosocial science, given the unique opportunity they provide to study how the life course is intergenerationally shaped. As many contributors for this series have highlighted, the what and how of biological and social transmission between kin are of central concern in cohort studies (Roberts 2019), even if this is sometimes often intensely focused on ‘mother-child’ dyads and early developmental stages of the life course (Lappe and Hein 2020), or singular kinds of social exposure, such as early adversity (Lloyd 2020, Kim 2020). Drawing on pilot study research with a small group of cohort participants from a UK based regional birth cohort, we reflect further on what Janelle Lamoreaux has called ‘cohort kinship’ (2019) by examining what it means to become intergenerational in birth cohorts. In doing so, we illuminate how both the ‘doing and being’ (McKinnon 2016) of kinship is temporally entangled with the (re)making of cohort participation. Here we extend recent social science work examining the relevance of relatedness and kinship to the meaning and experience of cohort participation and kinds of biosocial research carried out in birth cohort studies (Cruz et al forthcoming Kalender and Holmberg 2019). We see this as part of a wider effort to resituate kinship in studies of scientific practice (Carsten 2019) and re-invigorate what Gibbon and Lamoreaux (forthcoming) have termed ‘Intergenerational Ethnography’ in examining the making and unmaking of kin within and beyond the biosocial sciences

The Grizzly, March 2, 1984

Reagan Proposes to Cut Student Aid: 62% Ursinus Students Could Feel Bite • Tray Offenders Discussed • Students Elect New USGA Officers • Writing Seminar Features Alumni • Presidents Corner: Frats Move in Desirable Direction • Letters to the Editor: USGA Concerned With Student Apathy; Get in Gear • Board Elects Two New Members, Appoints Seven • Women\u27s Club Plans Events • WRUC Gets Technician • The Lantern Seeks Contributions • Cogger Heads State Study • Fall Registration Looms on Horizon • Learn While You Work • Sports Profile: Mo Gorman Excels • Basketball Team Wraps Up 83-84 Season • Bears Make Tracks • Grapplers Shine At MACs: Doyle Crowned 150lb Champ; Racich Named Coach of the Year • Doyle and Paolone Successful in MAC Competition • Satisfied with Nationalshttps://digitalcommons.ursinus.edu/grizzlynews/1114/thumbnail.jp

The Grizzly, March 2, 1984

Reagan Proposes to Cut Student Aid: 62% Ursinus Students Could Feel Bite • Tray Offenders Discussed • Students Elect New USGA Officers • Writing Seminar Features Alumni • Presidents Corner: Frats Move in Desirable Direction • Letters to the Editor: USGA Concerned With Student Apathy; Get in Gear • Board Elects Two New Members, Appoints Seven • Women\u27s Club Plans Events • WRUC Gets Technician • The Lantern Seeks Contributions • Cogger Heads State Study • Fall Registration Looms on Horizon • Learn While You Work • Sports Profile: Mo Gorman Excels • Basketball Team Wraps Up 83-84 Season • Bears Make Tracks • Grapplers Shine At MACs: Doyle Crowned 150lb Champ; Racich Named Coach of the Year • Doyle and Paolone Successful in MAC Competition • Satisfied with Nationalshttps://digitalcommons.ursinus.edu/grizzlynews/1114/thumbnail.jp

Association of Attitudes and Beliefs towards Antiretroviral Therapy with HIV-Seroprevalence in the General Population of Kisumu, Kenya

Since antiretroviral therapy (ART) became available in the developed world, the prevalence of unprotected sex and the incidence of sexually transmitted infections (STIs) and HIV have increased. We hypothesized that a similar phenomenon may be occurring in sub-Saharan Africa concomitant with the scale-up of HIV treatment.We conducted a general population-based survey in Kisumu, Kenya. Participants completed an interview that included demographics as well as ART-related attitudes and beliefs (AB) and then underwent HIV serological testing. Exploratory and confirmatory factor analyses of AB about ART indicated two factors: 1) ART-related risk compensation (increased sexual risk taking now that ART is available); and 2) a perception that HIV is more controllable now that ART is available. Logistic regression was used to determine associations of these factors with HIV-seroprevalence after controlling for age.1,655 (90%) of 1,844 people aged 15-49 contacted, including 749 men and 906 women, consented to participate in the study. Most participants (n = 1164; 71%) had heard of ART. Of those who had heard of ART, 23% believed ART was a cure for HIV. ART-related risk compensation (Adjusted (A)OR = 1.45, 95% CI 1.16-1.81), and a belief that ART cures HIV (AOR = 2.14, 95% CI 1.22-3.76) were associated with an increased HIV seroprevalence in men but not women after controlling for age. In particular, ART-related risk compensation was associated with an increased HIV-seroprevalence in young (aged 15-24 years) men (OR = 1.56; 95% CI 1.12-2.19).ART-related risk compensation and a belief that ART cures HIV were associated with an increased HIV seroprevalence among men but not women. HIV prevention programs in sub-Saharan Africa that target the general population should include educational messages about ART and address the changing beliefs about HIV in the era of greater ART availability

Development of a core outcome set for use in community-based bipolar trials-A qualitative study and modified Delphi.

BACKGROUND A core outcome set (COS) is a standardised collection of outcomes to be collected and reported in all trials within a research area. A COS can reduce reporting bias and facilitate evidence synthesis. This is currently unavailable for use in community-based bipolar trials. This research aimed to develop such a COS, with input from a full range of stakeholders. METHODS A co-production approach was used throughout. A longlist of outcomes was derived from focus groups with people with a bipolar diagnosis and carers, interviews with healthcare professionals and a rapid review of outcomes listed in bipolar trials on the Cochrane database. An expert panel with personal and/or professional experience of bipolar participated in a modified Delphi process and the COS was finalised at a consensus meeting. RESULTS Fifty participants rated the importance of each outcome. Sixty-six outcomes were included in Round 1 of the questionnaire; 13 outcomes were added by Round 1 participants and were rated in Round 2. Seventy-six percent of participants (n = 38) returned to Round 2 and 60 outcomes, including 4 outcomes added by participants in Round 1, received a rating of 7-9 by >70% and 1-3 by <25% of the sample. Fourteen participants finalised a COS containing 11 outcomes at the consensus meeting: personal recovery; connectedness; clinical recovery of bipolar symptoms; mental health and wellbeing; physical health; self-monitoring and management; medication effects; quality of life; service outcomes; experience of care; and use of coercion. CONCLUSIONS This COS is recommended for use in community-based bipolar trials to ensure stakeholder-relevant outcomes, facilitate data synthesis, and transparent reporting. The COS includes guidance notes for each outcome to allow the identification of suitable measurement instruments. Further validation is recommended for use with a wide range of communities and to achieve standardised measurement