Method of Estimating Calibration Accuracy for Capacitive Voltage Probe

Capacitive voltage probe (CVP) can measure the common mode disturbance voltages without contact to cables. A common-mode voltage needs to be measured using the calibration unit when a calibration of CVP is carried out. Therefore, the accuracy of calibration should be evaluated, because it is important for an EMC conformity test to confirm validity of a result obtained by CVP. This paper proposes the evaluation method for correction factor of calibration unit using S-parameters. The calibration accuracy was evaluated by the coefficient, αasm that was obtained from S-parameters of the calibration unit. The coefficient was calculated using FDTD method and was measured from 0.1 MHz to 100 MHz to evaluate the proposed method. The results indicated that the deviation between the calculated and measured value is within 0.6 dB from 0.1 to 30MHz. This means that the coefficient, αasm, is effective to evaluate the accuracy. The coefficient, αasm, was also measured using the calibration unit and CVP when a wire radius and a kind of cable were changed. The results indicated that the αasm was within 1 dB from 0.1 MHz to 30 MHz.2009 International Symposium on Electromagnetic Compatibility (EMC\u2709/Kyoto), July 20-24, 2009, Kyoto International Conference Center, Kyoto, Japa

Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration.

The gut incretin glucagon-like peptide-1 (GLP-1) and the intestinotropic hormone GLP-2 are released from enteroendocrine L cells in response to ingested nutrients. Treatment with an exogenous GLP-2 analogue increases intestinal villous mass and prevents intestinal injury. Since GLP-2 is rapidly degraded by dipeptidyl peptidase 4 (DPP4), DPP4 inhibition may be an effective treatment for intestinal ulcers. We measured mRNA expression and DPP enzymatic activity in intestinal segments. Mucosal DPP activity and GLP concentrations were measured after administration of the DPP4 inhibitor sitagliptin (STG). Small intestinal ulcers were induced by indomethacin (IM) injection. STG was given before IM treatment, or orally administered after IM treatment with or without an elemental diet (ED). DPP4 mRNA expression and enzymatic activity were high in the jejunum and ileum. STG dose-dependently suppressed ileal mucosal enzyme activity. Treatment with STG prior to IM reduced small intestinal ulcer scores. Combined treatment with STG and ED accelerated intestinal ulcer healing, accompanied by increased mucosal GLP-2 concentrations. The reduction of ulcers by ED and STG was reversed by co-administration of the GLP-2 receptor antagonist. DPP4 inhibition combined with luminal nutrients, which up-regulate mucosal concentrations of GLP-2, may be an effective therapy for the treatment of small intestinal ulcers