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    Additional file 5: of A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit

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    Figure S2. Hospital mortality in septic and non-septic critically ill patients during follow-up. At admission (first 72 hours in ICU), patients were categorized as No AKI and AKIN stages 1, 2 and 3, presented on x axis. Patients followed-up until day 7 to determine whether they improved to a lower AKIN stage or deteriorated to a more severe AKIN stage, presented on z axis. Hospital mortality determined for groups in which patients improved or deteriorated during follow-up. Patients with AKIN stage 3 at admission and at follow-up show highest mortality rate. Worsening of AKI is associated with higher mortality unrelated to AKI category at ICU admission. Graph also shows that patients with AKIN stage 3 at admission who improve to No AKI at follow-up still have twice as high mortality rates compared to patients with No AKI at admission and follow-up (PNG 30 kb

    Additional file 4: of A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit

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    Figure S1. RRT in critically ill patients with and without sepsis. A: Percentage of patients receiving RRT per day per AKIN stage at admission. B: RRT incidence per AKIN stage at follow-up. Admission category presented on x axis. Patients followed-up until day 7 to determine whether they improved to a lower AKIN stage or deteriorated to a worse AKIN stage, presented on z axis. In case of discharge or death, data were imputed by last observation carried forward (PNG 43 kb

    Additional file 3: of A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit

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    Table S1. Adjusted AKIN criteria for diagnosis of AKI. Table S2. RRT modality per day. Table S3. RRT and mortality per region and GNI. Table S4. RRT modality per region and GNI. Table S5. Length of stay per region and GNI. Table S6. Mortality per RRT modality. Table S7. Baseline demographic characteristics of patients with CRF, with and without sepsis. Table S8. Baseline clinical characteristics of patients with CRF, with and without sepsis. Table S9. Outcome of patients with CRF at admission (DOCX 48 kb
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