25 research outputs found

    Dynamic regime of ignition of solid propellant

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    This article presents a dynamic regime of exposure of the radiant flux on the sample of gun-cotton. Obtained time the ignition of gun-cotton in the heating conditions of increasing heat flux in the range from 0.2 W/cm2 to 22 W/cm2. A comparison of the delay times of the ignition when heated variable and constant heat flux

    Investigation of working processes in a flowing channel of ramjet engine

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    The technique and results of experimental-theoretical study of gas-dynamics, heat transfer and the structure of gas-flow in the flowing channel of a ramjet engine in Mach number range M = (5-7) are presented. The temperature distribution along the flowing channel of a ramjet engine was experimentally obtained. The temperature along the wall of the flowing channel of the axisymmetric model was measured using the developed thermoprobe. Distributions of Mach number and temperature along the symmetry axis of the flowing channel of the model are obtained numerically. Comparison of the numerical and experimentally obtained values of the Mach number showed their qualitative agreement

    Toolbox model of evolution of metabolic pathways on networks of arbitrary topology

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    In prokaryotic genomes the number of transcriptional regulators is known to quadratically scale with the total number of protein-coding genes. Toolbox model was recently proposed to explain this scaling for metabolic enzymes and their regulators. According to its rules the metabolic network of an organism evolves by horizontal transfer of pathways from other species. These pathways are part of a larger "universal" network formed by the union of all species-specific networks. It remained to be understood, however, how the topological properties of this universal network influence the scaling law of functional content of genomes. In this study we answer this question by first analyzing the scaling properties of the toolbox model on arbitrary tree-like universal networks. We mathematically prove that the critical branching topology, in which the average number of upstream neighbors of a node is equal to one, is both necessary and sufficient for the quadratic scaling. Conversely, the toolbox model on trees with exponentially expanding, supercritical topology is characterized by the linear scaling with logarithmic corrections. We further generalize our model to include reactions with multiple substrates/products as well as branched or cyclic metabolic pathways. Unlike the original model the new version employs evolutionary optimized pathways with the smallest number of reactions necessary to achieve their metabolic tasks. Numerical simulations of this most realistic model on the universal network from the KEGG database again produced approximately quadratic scaling. Our results demonstrate why, in spite of their "small-world" topology, real-life metabolic networks are characterized by a broad distribution of pathway lengths and sizes of metabolic regulons in regulatory networks.Comment: 34 pages, 9 figures, 2 table

    Mathematical modelling of the liquid atomization process by cocurrent gas flow

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    This paper focuses on the physical-mathematical model of liquid atomization in the spray pattern of an ejection nozzle. A flow field of a gas phase behind the nozzle section is computed using the Ansys Fluent package. Dynamics of molten metal droplets in the gas phase within a trajectory approach is calculated. Using the presented model, numerical calculation results are given

    Instability of coherent states of a real scalar field

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    We investigate stability of both localized time-periodic coherent states (pulsons) and uniformly distributed coherent states (oscillating condensate) of a real scalar field satisfying the Klein-Gordon equation with a logarithmic nonlinearity. The linear analysis of time-dependent parts of perturbations leads to the Hill equation with a singular coefficient. To evaluate the characteristic exponent we extend the Lindemann-Stieltjes method, usually applied to the Mathieu and Lame equations, to the case that the periodic coefficient in the general Hill equation is an unbounded function of time. As a result, we derive the formula for the characteristic exponent and calculate the stability-instability chart. Then we analyze the spatial structure of the perturbations. Using these results we show that the pulsons of any amplitudes, remaining well-localized objects, lose their coherence with time. This means that, strictly speaking, all pulsons of the model considered are unstable. Nevertheless, for the nodeless pulsons the rate of the coherence breaking in narrow ranges of amplitudes is found to be very small, so that such pulsons can be long-lived. Further, we use the obtaned stability-instability chart to examine the Affleck-Dine type condensate. We conclude the oscillating condensate can decay into an ensemble of the nodeless pulsons.Comment: 11 pages, 8 figures, submitted to Physical Review

    Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response

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    Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of environmental stress or other specific stress response mechanisms and the second order selection which states that mutators hitchhike to fixation with unrelated beneficial alleles. Conventional population genetics models could not fully resolve this controversy because they are based on certain assumptions about fitness landscape. Here we address this problem using a microscopic multiscale model, which couples physically realistic molecular descriptions of proteins and their interactions with population genetics of carrier organisms without assuming any a priori fitness landscape. We found that both pleiotropy and second order selection play a crucial role at different stages of adaptation: the supply of mutators is provided through destabilization of error correction complexes or fluctuations of production levels of prototypic mismatch repair proteins (pleiotropic effects), while rise and fixation of mutators occur when there is a sufficient supply of beneficial mutations in replication-controlling genes. This general mechanism assures a robust and reliable adaptation of organisms to unforeseen challenges. This study highlights physical principles underlying physical biological mechanisms of stress response and adaptation
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