Comparison of serum levels of thyroidstimulating hormone in preeclampsia and non-preeclampsia pregnant women referring to Karaj Kamali Hospital in 2018

Introduction: As there is no reliable criterion for early diagnosisof preeclampsia up to present date, this study wasconducted to compare the serum levels of thyroid-stimulatinghormone in preeclampsia and non-preeclampsiapregnant women and the use of thyroid-stimulating hormone(TSH) as a predictive factor in preeclampsia.Method: In this case-control study, 45 non-preeclampsiapregnant women and 45 preeclampsia pregnant womenin the third trimester of pregnancy referred to Kamali Hospitalof Karaj were examined. A skilled person took 10 ccof venous blood of the subjects and the mean serum TSHlevels of both groups were compared by using SPSS, version22, software.Results: The mean serum TSH level was 2.55 ± 1.13 and3.08 ± 1.23, respectively, in non-preeclampsia pregnantwomen and preeclampsia pregnant women, the relationshipwas statistically significant (P =0.013). Besides, theprevalence of preterm delivery in preeclampsia pregnantwomen was higher than that in non-preeclampsia pregnantwomen (P = .000). The mean weight of neonatesin preeclampsia pregnant women was lower than that innon- preeclampsia pregnant women (P = .000).Conclusion: This study revealed that measuring serumTSH levels in the third trimester of pregnancy could be apredictor of preeclampsia

Vitamin D Status in Pregnant Women and Their Newborns in Karaj: A Cross-Sectional Study in Iran

Background Pregnant women and newborns are at risk of vitamin D deficiency. This study aimed to determine the vitamin D status in pregnant women andtheir newborns in Karaj, Iran. Materials and Methods This cross-sectional study was conducted from March 2014 to October 2015. A total of 151 pregnant women and 154 newborns (three twin cases) were included in the study. After obtaining 5 ml venous blood samples from mothers and 5 ml blood from the umbilical cord of newborns, 25-hydroxy vitamin D [25(OH)D] was measured by ELISA method. Serum level of 25(OH)D below 20 ng/ml was considered deficiency, 21-29 ng/ml was considered insufficient and 30-100 ng/ml was considered sufficient. Data were analyzed using SPSS software version 20.0. Results The prevalence of vitamin D deficiency and its insufficiency was 93.5% and 6.5% for pregnant women, 94.2% and 3.9% for newborns, respectively. The mean 25(OH)D concentration in pregnant women and newborns was estimated to be 10.649±5.967 ng/ml and 10.574±6.280 ng/ml, respectively. There was a significant correlation between the mean 25(OH)D concentration in mothers and their newborns (r=0.913 and

Comparison of serum levels of thyroidstimulating hormone in preeclampsia and non-preeclampsia pregnant women referring to Karaj Kamali Hospital in 2018

Introduction: As there is no reliable criterion for early diagnosisof preeclampsia up to present date, this study wasconducted to compare the serum levels of thyroid-stimulatinghormone in preeclampsia and non-preeclampsiapregnant women and the use of thyroid-stimulating hormone(TSH) as a predictive factor in preeclampsia.Method: In this case-control study, 45 non-preeclampsiapregnant women and 45 preeclampsia pregnant womenin the third trimester of pregnancy referred to Kamali Hospitalof Karaj were examined. A skilled person took 10 ccof venous blood of the subjects and the mean serum TSHlevels of both groups were compared by using SPSS, version22, software.Results: The mean serum TSH level was 2.55 ± 1.13 and3.08 ± 1.23, respectively, in non-preeclampsia pregnantwomen and preeclampsia pregnant women, the relationshipwas statistically significant (P =0.013). Besides, theprevalence of preterm delivery in preeclampsia pregnantwomen was higher than that in non-preeclampsia pregnantwomen (P = .000). The mean weight of neonatesin preeclampsia pregnant women was lower than that innon- preeclampsia pregnant women (P = .000).Conclusion: This study revealed that measuring serumTSH levels in the third trimester of pregnancy could be apredictor of preeclampsia

Comparison of serum levels of thyroidstimulating hormone in preeclampsia and non-preeclampsia pregnant women referring to Karaj Kamali Hospital in 2018

Introduction: As there is no reliable criterion for early diagnosisof preeclampsia up to present date, this study wasconducted to compare the serum levels of thyroid-stimulatinghormone in preeclampsia and non-preeclampsiapregnant women and the use of thyroid-stimulating hormone(TSH) as a predictive factor in preeclampsia.Method: In this case-control study, 45 non-preeclampsiapregnant women and 45 preeclampsia pregnant womenin the third trimester of pregnancy referred to Kamali Hospitalof Karaj were examined. A skilled person took 10 ccof venous blood of the subjects and the mean serum TSHlevels of both groups were compared by using SPSS, version22, software.Results: The mean serum TSH level was 2.55 ± 1.13 and3.08 ± 1.23, respectively, in non-preeclampsia pregnantwomen and preeclampsia pregnant women, the relationshipwas statistically significant (P =0.013). Besides, theprevalence of preterm delivery in preeclampsia pregnantwomen was higher than that in non-preeclampsia pregnantwomen (P = .000). The mean weight of neonatesin preeclampsia pregnant women was lower than that innon- preeclampsia pregnant women (P = .000).Conclusion: This study revealed that measuring serumTSH levels in the third trimester of pregnancy could be apredictor of preeclampsia

Studying the Effect of Wearing Compression Socks on Hypotension and the Amount of Administrated Ephedrine after Spinal Anesthesia in the Candidates for Cesarean Section

Background and objectives: Due to the negative effects and risks of general anesthesia for the mother and fetus, spinal anesthesia has been the preferred method of anesthesia for cesarean section. Nevertheless, this method has its own disadvantages and side effects, which must be prevented or treated through effective approaches. This study evaluates the effect of wearing compression socks on degree of hypotension and ephedrine administration after spinal anesthesia in candidates for cesarean section.  methods: In this clinical trial, 80 candidates for cesarean section were equally divided into an intervention group and a control group. Immediately after spinal anesthesia, the patients were worn compression socks from the tip of the toe fingers up to the knees. Blood pressure was measured and recorded just before spinal anesthesia and every 5 minutes after, for 30 minutes. The recorded data were analyzed by SPSS (version 19). Results: The mean blood pressure recorded 5 minutes and 15 minutes after spinal anesthesia differed significantly between the two groups (P<0.05). Moreover, ephedrine was not administered for the patients in the intervention group in the first 5 minutes after spinal anesthesia. Conclusions: Considering the positive effects of wearing compression socks on the anesthesia-induced hypotension and amount of ephedrine administration, this non-invasive method is highly recommended for cesarean section candidates who undergo spinal anesthesia

The comparison of pregnancy outcomes in fresh and frozen embryo transfer: A cross-sectional study

Abstract Background: The benefits of frozen embryo transfer (FET) vs. fresh embryo transfer for in vitro fertilization (IVF) have been discussed in previous studies. Objective: To determine and compare the pregnancy outcomes following FET and frozen embryo transfer in women who underwent assisted reproductive techniques. Materials and Methods: In this cross-sectional study, 233 women candidates for IVF/intra cytoplasmic sperm injection who referred to the Kamali Training Medical Center, Karaj, Iran during 2019-2020 were evaluated in 2 groups of fresh (n = 127) and frozen (n = 106) embryo transfers. The rates of pregnancy outcomes including chemical and clinical pregnancy, live birth, preeclampsia, ectopic pregnancy, still birth, and pregnancy loss were compared between groups in 3 age subgroups ( < 25, 25-35, and 35-40 yr old). Results: No significant difference in terms of chemical and clinical pregnancy and live birth rates were observed between groups in women aged < 25 yr. Chemical and clinical pregnancy and live birth rates were significantly higher in the FET group compared to fresh group in 25-35-yr-old women (p = 0.01, p = 0.03, and p = 0.01, respectively). In 35-40-yr-old women, no significant differences were observed in terms of chemical and clinical pregnancy rates, but live birth rate was found to be significantly higher in the FET group (p = 0.02). The pregnancy loss was lower in the FET group (p = 0.038). Conclusion: In conclusion, the FET method in women aged 25-35 yr significantly increases the chance of successful IVF/intra cytoplasmic sperm injection

Prevalence of diabetes in women with preeclampsia referred to Imam Hossein and Fatemieh Hospitals in Shahroud

Introduction and objective: Preeclampsia, characterised by hypertension and proteinuria occurring after 20 gestational weeks, is a leading cause of maternal and foetal morbidity and mortality . The pathophysiology of preeclampsia remains elusive, and &nbsp;the incidence of diabetes during pregnancy in patients with preeclampsia is still a mather of study. Therefore, the objective of this study was to investigate the prevalence of diabetes in women with preeclampsia referred to Imam Hossein and Fatemieh hospitals in Shahroud. Methodology: This descriptive cross-sectional study was conducted on 108 women with preeclampsia (based on clinical symptoms, gynecological tests, and diagnoses) referred to Fatemieh and Imam Hossein hospitals in Shahroud for delivery or termination of pregnancy in 2014. A questionnaire, which included demographic information such as age, number of pregnancies, birth rank, pregnancy conditions, type of delivery, history of hypertension and diabetes in the patient and their first-degree relatives, was used in this study. Data were expressed as percentage, frequency, standard deviation, mean, and were analyzed by Student's t test and chi-square, using SPSS software. A value of p&lt;0.05 was considered significant. Results: The incidence of preeclampsia was associated with maternal diabetes (p&le;0.05), maternal age (p&le;0.04), birth rank (p&le;0.04), multiple pregnancies (p&le;0.03), history of maternal diabetes, history of maternal hypertension (p&le;0.03), history of preeclampsia at previous delivery (p&lt;0.02) and age of termination of pregnancy (p&le;0.01). There was no significant difference with regard to other variables. Conclusion: The results revealed that about 25% of preeclampsia patients had gestational diabetes, which increased the risk in pregnant women and neonates. Therefore, by preventing and controlling blood pressure and diabetes, we can reduce the maternal and fetal complications of these disorders, and thus, reduce the rate of mortality

Comparison of the effect of intravenous epinephrine and ephedrine in the management of hypotension and bradycardia during cesarean section under spinal anesthesia in Kamali Hospital, Karaj

Introduction: hypotension and bradycardia are two underlying and almost common complications caused by spinal anesthesia in cases of elective cesarean section (CS). Suitable treatment of the complications is particularly important to improve the conditions of patients. Hence, the aim of this study is to compare the effect of intravenous administration of epinephrine and ephedrine in the management of hypotension and bradycardia caused by CS spinal anesthesia. Method: the study was done as a random clinical trial on 126 women under spinal anesthesia for elective CS, hospitalized in Kamali Hospital, Karaj in 2020-21. The statistical samples were classified into two ephedrine and epinephrine. &nbsp;Patients systolic blood pressure, diastolic blood pressure, heart rate and Apgar and VBG of the newborn were analyzed in two study groups. Results: The results showed that the mean value of diastolic blood pressure, which was the same in the two groups at the beginning, was significantly increased in the ephedrine group compared to the epinephrine group from minute eight. Mean systolic blood pressure, which was the same in the two groups at the beginning, was significantly increased in the ephedrine group compared to the epinephrine group in minutes 8-16. However, they showed no significant difference in the rest of the evaluations. The mean value of heart rate that was the same between the two groups at the beginning was significantly increased in the ephedrine group in minutes 10, 25, 35, and 45; although the two groups showed no significant difference in other times assessed. The mean value of PCO2 and HCO3 showed a significant difference between the two groups, and both were higher in the ephedrine group. Conclusion: Our results indicate that intravenous ephedrine compared to intravenous epinephrine produces a higher increasing the values blood pressure and heart rate in the management of hypotension and bradycardia caused by spinal anesthesia in the cases of elective cesarean section