Mary Schweitzer Papers - Accession 1490

The Mary Schweitzer Papers consists of publications, a scrapbook, collections of professional papers, and an academic publication/thesis belonging to Dr. Mary Schweitzer, Winthrop Anthropology Professor. Dr. Schweitzer is a cultural anthropologist who came to Winthrop in 1978 and retired from fulltime teaching in 2000. She was also a visiting professor at the American University – Central Asia in Bishkek, Kyrgyzstan (2002-03 and 2004-05) and in the Aga Khan (Muslim-Ismaili) Humanities Project in Dushanbe, Tajikistan (2006). She has received Fulbright awards for travel, study and teaching in Colombia, South America (1984), India (1988), and Albania (2001) and traveled extensively in China, Peru, Bulgaria, Turkey, and Mexico. The list of her published articles and presentations is long, including five presentations at meetings of the American Anthropological Association from 1976 to 1991.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/2449/thumbnail.jp

Identification of Immunoreactive Material in Mammoth Fossils

The fossil record represents a history of life on this planet. Attempts to obtain molecular information from this record by analysis of nucleic acids found within fossils of extreme age have been unsuccessful or called into question. However, previous studies have demonstrated the long-term persistence of peptides within fossils and have used antibodies to extant proteins to demonstrate antigenic material. In this study we address two questions: Do immunogenic/antigenic materials persist in fossils? and; Can fossil material be used to raise antibodies that will cross-react with extant proteins? We have used material extracted from a well-preserved 100,000-300,000-year-old mammoth skull to produce antisera. The specificity of the antisera was tested by ELISA, western blotting, and immunohistochemistry. It was demonstrated that antisera reacted specifically with the fossils and no the surrounding sediments. Reactivity of antisera with modern proteins and tissues was also demonstrated, as was the ability to detect evolutionary relationships via antibody-antigen interactions. Mass spectrometry demonstrated the response of amino acids and specific peptides within the fossil. Peptides were purified by anion-exchange chromatography and sequenced by tandem mass spectrometry. The collagen-derived peptides may have been the source of at least some of the immunologic reactivity, but the antisera identified molecules that were not observed by mass spectrometry, indicating that immunologic methods may have greater sensitivity. Although the presence of peptides and amino acids was demonstrated, the exact nature of the antigenic material was not fully clarified. This report demonstrated that antibodies may be used to obtain information from the fossil record

Cellular metabolism as a basis for immune privilege

We hypothesize that the energy strategy of a cell is a key factor for determining how, or if, the immune system interacts with that cell. Cells have a limited number of metabolic states, in part, depending on the type of fuels the cell consumes. Cellular fuels include glucose (carbohydrates), lipids (fats), and proteins. We propose that the cell's ability to switch to, and efficiently use, fat for fuel confers immune privilege. Additionally, because uncoupling proteins are involved in the fat burning process and reportedly in protection from free radicals, we hypothesize that uncoupling proteins play an important role in immune privilege. Thus, changes in metabolism (caused by oxidative stresses, fuel availability, age, hormones, radiation, or drugs) will dictate and initiate changes in immune recognition and in the nature of the immune response. This has profound implications for controlling the symptoms of autoimmune diseases, for preventing graft rejection, and for targeting tumor cells for destruction

The MASSE Project: Applications of Biotechnology for Planetary Exploration

Automated life-detection experiments for solar system exploration have been previously. proposed and used onboard the. Viking, Mars lander,s, although. with ambiguous results. The recent advances in biotechnology such as biosensors, protein microarrays, and microfluidics alongside increased. knowledge in biomarker science have led to vastly improved sophistication and sensitivity for a new approach in life detection. The MASSE project has taken the challenge of integrating all of this knowledge into a new generation of interplanetary flight instrumentation for the main purpose.ot combining several mutually. confirming tests for life, organic/microbial contamination, prebiotic and abiotic chemicals into a small low powered instrument. Although the primary goal is interplanetary exploration, several terrestrial applications have become apparent specifically in point-of-care medical technology, bio-warfare, environmental sensing and microbial monitoring of manned space-flight vehicles

Marx - From Hegel and Feuerbach to Adam Smith : a New Sysnthesis

In The Economic and Philosophical Manuscripts of 1844 (completed in August 1844) Marx takes two crucial steps in the formation of his worldview. The first relates to his rejection of all 'old' materialism, including Feuerbach's, and the adoption of his own version, which he called 'communist', 'practical'. This view was later presented definitively in the first Thesis on Feuerbach (spring of 1845), and elaborated in The German Ideology (1845-46). The second step relates to Marx's synthesising of the philosophical standpoint that he had developed up to this point (around the spring of 1844) with political economy. Up to this point he had spoken of alienation in largely philosophical terms; now it is rooted in the process of production. On both counts Adam Smith was an important influence. This claim provides the focus of this paper. To make this point successfully I have found it necessary to briefly trace the development of Marx's philosophical standpoint up to the writing of the Manuscripts, and to distinguish between the two methodologically distinct aspects of Adam Smith's thought, the one that Marx accepted and the other that he rejected

The Ursinus Weekly, October 15, 1951

Henning W. Prentis slated as speaker at Founders\u27 Day program, October 24 • Chaplain first Forum speaker on October 31 • Curtain Club adds sixty new members at annual party • New preceptress in charge of 646 Main • 300 books added to Library collection • Piano recital date moved to Nov. 8 • Cub and Key honor given to Jay Kern • Y plans weekend trip, arranges fireside chats • Date announced for civil service exam • WAA to sell socks, Christmas cards • Soph class plans year; Informal dance Nov. 3 • French Club discusses plans • Rev. Creager to speak • Juniors to sponsor G. E. House of Magic • German Club schedules trips and welcomes Inge Rudloff • 12 students become psychology majors • Spirit Committee fans campus enthusiasm • Editorials: No complaints; British voters go to polls; McCarthy vs. free speech • Letter to the editor • Dorm initiations give jokers a release • So the frosh love customs? Scribes of 1955 reveal all • Dr. Miller\u27s family hits high spots in European tour • Four teams open intradorm football • Hockey and soccer are overshadowed, but fortunately have excellent leaders • Dickinson hands Ursinus season\u27s second defeat • Dr. Roelofs keeps athletes in shape • Garnet eleven will play host to Bears Saturday • Alumnae team is undefeated; Faces Owlettes on Saturday • Harry Spangler succeeds Gerry Seeders as head coach of Ursinus court team • Bears defeated by Stevens Tech • Rittenhouse, Feldt to manage girls intramural program • Beardwood Chemical Society hears lecture on narcotics • Lit reading givenhttps://digitalcommons.ursinus.edu/weekly/1523/thumbnail.jp

The Ursinus Weekly, May 21, 1951

Dr. Allan L. Rice confers with Senator E. Kefauver • Awards given to athletes at WAA banquet • Reading Railroad president to address Newcomen group here • WSGA installs new officers at banquet • Curtain Club elects Roberts • Bowens join honorary debating frat, Tau Kappa • Lantern issue due • Y picnic held • Dean Harry A. Cochran to address senior class • MSGA gives out concessions for 1951-52 year • Ruby to arrive shortly; Seniors plan class gift • Various campus groups hold annual elections, installations • Editorials: Backward glance • World escapism attacked; News awareness asked • Poll reveals students\u27 plans • Seniors review elements in their past, grow maudlin as graduation approaches • Scheduling problems plague students, faculty; Difficulties cause practice teachers to groan • Softball team scores two more victories • Dickinson loses to Ursinus nine • Ursinus girls beat East Stroudsburg squad in tennis • Luckless Bruins lose to Lehigh track team • Garnet team halts Millermen\u27s streak; LaSalle defeated, 5-4, to close season • Curtis I crowned softball champs • Cindermen place sixth in Middle Atlantics • Penn girls defeat Ursinus in tennis • Hal Henning\u27s circuit blast beats Drew; Wild pitch defeats Delaware in eleventh • Zeta Chi takes inter-frat track • Health, welfare council meets at Ursinus; Elect new officers • Note of thankshttps://digitalcommons.ursinus.edu/weekly/1570/thumbnail.jp

The Ursinus Weekly, April 16, 1951

May Day cast chosen; Practices begin this week • Arsenic and Old Lace is underway • Methods discussed by archaeologist • John Billman named head of IRC for coming year • McClure urges students to take army tests • French Club to present pianist, vocalists in recital • 35 Weekly workers honored at banquet • Varsity Club plans big weekend; Variety show, dance listed April 27, 28 • Ursinus to be honored by Newcomen Society May 24 • Self-help jobs available; Letters must be written • Many jobs available to Spring graduates • \u2751ers forced to break up as Fisher must leave for U.S. Navy service • Editorials: Opinions sought; Honor comes to Ursinus • Letters to the editor • Advice to book buyers • Truman decision upheld • Junior Prom traditions seen through years; Theme varies • Poll reveals students\u27 views on MacArthur ouster • Local character, Little Mink, writes parents about college • Preparing catalogue is year-round job, Dr. Phillips says • Moravian beats Ursinus in first home game, 7-3 • Mrs. Whiting stars as player, coach • Bruin team loses fourth straight to Temple nine • Bears defeated in trial meet • Movie to be shown • Two fireside chats planned for separate meetings April 18https://digitalcommons.ursinus.edu/weekly/1565/thumbnail.jp

The Ursinus Weekly, January 14, 1952

MSGA to enforce campus parking; new fines listed • Navy to send officer here for interviews • FTA hears lecture on visual aid subject • Dr. Phillips attends meeting of foreign student advisors • Forum speaker evaluates Middle East in address • May Queen petitions to go out Feb. 4; Pageant deadline set for February 27 • Rosicrucians add members; Tea is planned • Professors\u27 panel needs questions • Music Club picks Spring operetta • Interest lack hits debating society • Dolman to read • Music Club gives annual recital featuring students • Delta Pi Sigma pledges to work to improve campus • Re-election for Ruby business manager planned by Juniors • Editorials: Is it fair?; We still like heroes • Letters to the editor • English college rules differ from Ursinus\u27 • Engagement announced • Birth announced • Chess provides ground for exercise of mind\u27s caution, logic, memory • Projects planned for improvement of Y rec center • Boobies run acoustics in Bomberger • Bruins topple Haverford 76-59 for first league court victory • Wrestlers defeated by Lafayette team • Marguerite Spencer is chosen captain of 1952 girls\u27 basketball squad • Dorm squads battle for campus court crown • Mack assigned • Bruins register four pins to down Garnet matmen • New record set • Delaware beats Ursinus, 81-52 • Sorority members hold partieshttps://digitalcommons.ursinus.edu/weekly/1532/thumbnail.jp