Wound Healing Ethnomedicinal Plants Popular among the Malayali Tribes in Vattal Hills, Dharmapuri, TN, India

Healing of chronic lower extremity wounds is a global problem, especially in developing countries where traditional medicine is often used by the people in remote places. India has a rich tradition of plant based knowledge pertinent to healthcare. A survey of ethnomedicinal plant species used by Malayali’s to heal cut/ wounds in Vattal Hills of Dharmapuri was made. A large number of plants/ extracts/ decoctions/ pastes are used by tribals to heal wounds, cuts and burns. In the present study, an attempt has been made to document ethnobotanical knowledge base and methods employed by Malayali’s for treatment of cut/ wounds. A large number of ethnomedicinal plants used by the Malayali’s have not been validated for wound healing potential. The present investigation resulted in the identification of 82 medicinal plant species distributed across 39 families that are used by Malayali’s to heal cut/ wounds. This study is an attempt to gather the information on the existing ethnobotanical knowledge base and document the traditional claims toward the development of safe of effective herbal drugs for cut/ wounds. Results of the study is organized in table form depicting the botanical name, family, vernacular name and habit with a brief note on plant parts used and method of administration

Sustainable substrates for targeted nutrient delivery in urban farming

There is tremendous interest in the development of alternative sustainable hydroponic substrates to replace currently unsustainable options. Utilising organic wastes in highvalue applications can promote sustainable agriculture through the formation of a circular economy loop. In this study, sugar-mediated porogen leaching was explored in keratin-based substrates that have been synthesised for use in a hydroponic setting. The aim was to obtain larger porous structures within the substrates to enhance plant growth, and this was achieved, with increasing sugar concentration resulting in larger porous structures within the substrates. Positive results were also obtained with respect to plant growth studies; however, the reflected data is not solely based on larger pores because the retention of sugars within the substrates also contributed to better plant growth profiles. Therefore, further development is required in the porogen leaching process to eliminate any residual sugars that are retained within the substrates so that more precise conclusions can be made regarding the effectiveness of sugar-mediated porogen leaching in keratin-based substrates.Bachelor of Engineering (Materials Engineering

Quantifying the Effects of Smooth View Transitions on Perceptual Constancy in Node-Link Diagrams

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ABSTRACT We investigated the antihyperlipidemic activity of a polyherbal drug (Geriforte). The present study was undertaken to assess body weight, total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and very low density lipoprotein (VLDL) potential of the polyherbal drug (Geriforte) using atherogenic diet induced hyperlipidemia. The animals were divided into four groups: normal control, hyperlipidemic control, hyperlipidemic plus Geriforte and hyperlipidemic plus Ayurslim. Hyperlipidemia was induced by treated orally with butter fat (79% standard diet + 21% butter fat). Intragastric administration of Geriforte (450 mgkg -1 body weight) for 8 days significantly decreased body weight, TC, TG and LDL and VLDL whereas significantly increased level of HDL. Atherogenic index was lowered in the Geriforte drug fed animals when compared to hyperlipidemic animals. Geriforte exhibited quite competitive potential when compared with the reference drug Ayurslim affording a possible alternative therapeutic drug in the treatment of hyperlipidemia

HYPOLIPIDEMIC ACTIVITY OF HARITAKI (TERMINALIA CHEBULA) IN ATHEROGENIC DIET INDUCED HYPERLIPIDEMIC RATS

Haritaki (Terminalia chebula) family Combretaceae is an important plant used traditionally for medicinal purposes. It is component of the classic Ayurvedic combination called “Triphala”. Hyperlipidemia was induced by treated orally with atherogemc diet. In atherogenic diet induced hyperlipidemic model, the rats receiving treatment with Haritaki showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Haritaki was found to possess significant hypolipidemic activity. The results also suggest that Haritaki at 1.05 and 2.10 mg/kg b.wt. concentrations are an excellent lipid-lowering agent

Effects of Phyllanthus reticulatus on lipid profile and oxidative stress in hypercholesterolemic albino rats

Objective: This study was designed to investigate the effect of Phyllanthus reticulatus on lipid profile and oxidative stress in hypercholesterolemic albino rats. Materials and Methods: Hypercholesterolemia was induced in albino rats by administration of atherogenic diet for 2 weeks. Experimental rats were divided into different groups: normal, hypercholesterolemic control and P. reticulatus treated (250 and 500 mg/kg body weight doses for 45 days). After the treatment period of 45 th day triglyceride, VLDL-cholesterol, HDL-cholesterol, total cholesterol (TC), LDL-cholesterol and oxidative stress (protein carbonyl) were assayed and compared with hypercholesterolemic control. Results: The aqueous extract of P. reticulatus (250 mg and 500 mg/kg) produced significant reduction (P < 0.05) in triglyceride, VLDL-cholesterol, total cholesterol (TC), LDL-cholesterol and oxidative stress (protein carbonyl) while increased HDL-cholesterol in atherogenic diet-induced hypercholesterolemic rats at the end of the treatment period (45 days). However, the reduction in the above parameters was comparable with hypercholesterolemic control. Thus, aqueous extract of P. reticulatus is effective in controlling TC, lipid profile and oxidative stress in hypercholesterolemic animals. Conclusion: The results suggest the aqueous extract of P. reticulatus can be utilized for prevention of atherosclerosis in hypercholesterolemic patients