Motivation der arbeit in deutschen unternehmen und umsetzungsmöglichkeiten in der Ukraine

Arbeiten in einheimischen Unternehmen zu entwickeln, ist es ratsam, die mentalen Merkmale und nationalen Traditionen zu berücksichtigen, um zu unterscheiden, worauf sich die Manager in diesem Aspekt genau konzentrieren sollten

Vermicompost effect on the trace elements distribution in the luvic chernozem of the Krasnoyarsk forest-steppe

n the field experiment (2016-2018) in the conditions of the Krasnoyarsk forest-steppe the number of trace elements mobile forms were determined and the effect of soil organic matter and increasing doses of vermicompost on their distribution in luvic chernozem was studied. It is established that the studied vermicompost does not pollute the soil, which allows its widespread use in agriculture. The correlation and regression analysis obtained linear regression equations that reflect the relationship of the chemical element and organic matter in the soil after using increasing doses of vermicompost adequately. Elements with positive correlation and high significance level include Mn, Cu, Co and Zn

Thymosin β4 as basis for creation of a reparation preparation of new generation

On the basis of its multipurpose activities during regeneration of fabrics in various experiments on animals, Thymosin β4 has the potential for new researches, in kidneys and a liver, and also recovery of a spinal cord, bones and injury of ligaments. Besides, it can be useful in case of treatment of a wide range of other diseases, including concerning consequences of old bacterial damages and viral infection

Neuroprotective effects of the novel ethylthiadiazole derivatives (LHT 4-15) in male rats

The study was performed on male rats of the Wistar line. The animals were simulated with total cerebral ischemia with preliminary administration of LHT 4-15 compounds in doses of 25 and 50 mg/kg for 60 min. The data obtained from the neurological deficit and in the behavioral tests of the experimental groups confirm the theory of the presence of ethylthiadiazole derivatives under the LHT code 4–15 neuroprotective properti

PROFESSIONAL DEVELOPMENT OF CIVIL SERVANTS IN THE CONTEXT OF THE DIGITAL TRANSFORMATION

Digital transformation in governance is possible subject to a change in the corporate culture of the federal authorities. Training and a modern system of professional development of public authorities based on digital solutions and requiring digital skills are becoming the most important tool for changing culture. At the same time, the digitalization of the processes of organizing the professional development of civil servants is impossible without improving this system, including building interconnection with the development strategy of the state body (sphere, department), the system for assessing and motivating civil servants, and their career development. The approaches to planning the professional development of civil servants, quality assessment and examination of educational programs require updating. These processes must be based on modern digital solutions and services. The object of the research is the activities of state bodies and subdivisions regulating the sphere of professional development of civil servants. The purpose of the study is to develop proposals for improving the system of professional development of public authorities in the context of the government digital transformation. The tasks are related to the analysis of the current state of the professional development system in public authorities, the development of proposals for improving the system of professional development in governance in the context of digitalization and client (citizen) centricity. The novelty of the research is determined by the introduction of new state data of the professional development system of civil servants and the proposed model of the system maturity levels under study. The research is based on a systemic approach and a comparative method. The following empirical methods are used: sociological research (in-depth interviews, polls of civil servants); analysis of documents, expert sessions; modeling. The result of the research was the development of proposals for improving the system of professional development in the aspect of creating unified methodological approaches to the professional development of civil servants. The main conclusions relate to the application of the maturity level model of this system and the possibility of its use to update the existing approaches and methodological tools. A special place is occupied by proposals for the improvement of the Unified Information System for Personnel Management of the State Civil Service of Russia (EISU KS) and the Unified Specialized Information Resource (EIR) services for professional development of civil servants. The results of research can be used in the interests of federal authorities and regional governments, the Office of the President of the Russian Federation for Civil 7 Service and Personnel, the Human Resources Department of the Government of the Russian Federation, the Ministry of Labor and Social Protection of the Russian Federation to improve work on the professional development of civil servants. The prospects of the study are associated with the implementation of the proposed model of maturity levels and the development of methodological tools for moving to higher levels in terms of organizing professional developmen

Ion channel TRPA₁ is a promising therapeutic target for treatment of pain

In the last time information about the role of TRPA₁ in pain and cold sensitivity, as well as in the formation and maintenance of inflammation is increasing in scientific literature. Given this information, the interest for search and study of pharmacological agents, which selectively blocked of TRPA₁ and reduced the severity of pain and inflammation is increasin

Synthesis of Carboxymethyl Starch for increasing drilling mud quality in drilling oil and gas wells

This paper describes the impact of carboxymethyl starch preparation conditions on physicochemical properties of polysaccharide reagent, widely used as fluid loss reducing agent in drilling mud. Variation of the main parameters of carboxymethylation is researched in the experiment. The following conditions such as temperature and reaction time, amount of water, as well as ratio of NaOH to monochloracetic acid define the characteristics of carboxymethyl starch. The degree of substitution is defined for polysaccharides, as well as the characteristics of samples have been studied by infrared spectroscopy. Rheological characteristics and fluid loss indicator have been investigated to study the impact of the reagents on drilling mud quality

Cholera in Azov area

The purpose of research is analysis of clinical course and treatment results of patients with cholera in the Azov area. Materials and methods. During the period from 29.05.2011 to 19.08.2011 33 cases of cholera (32 adults and 1 child) and 25 vibrio carriers (22 adults and 3 children), which were caused by toxigenic strains of Vibrio cholera El Tor serogroup O1 Ogawa. Results. Likely factors of disease transmission in Mariupol are sea and river water, and the fish that were caught in the waters of the city. Typical and watery diarrhoea, vomiting, abdominal pain and lack of normal body temperature, dehydration syndrome, characterized clinical cholera for adults in most cases. The mean duration of diarrhoea was 6,6 days. At 46.9% observed atypical symptoms in 10 (31,3%) – abdominal pain (1 patient cramping in 7 cases, localized in the epigastria region, at 2-over stomach). In 5 patients (15,6%) had an increase in body temperature to 37,2–37,7 degrees Celsius. In 15 (46,9%) patients had severe nausea accompanied by vomiting. Easy for cholera was observed in 1 (3.1%), moderate – in 14 (43,8%), heavy – in 17 (53,1%) patients. Dehydration I level is set at 4 (12,5%), II – from 6 (18,7%), III – in 18 (56,3%), IV – 4 (12,5%) patients. Cholera outbreak was characterized by a predominance of severe disease and severe dehydration (III and IV), which was observed in 68.8% of patients. The decisive factor in the treatment of cholera patients was initiated in a timely manner rehydration therapy, in particular the introduction of the solution «Trisol». Against the background of rehydration therapy hyperkalaemia was observed in 9,4% of cases, vascular rehydration at 9,4%, the cell rehydration in 3,1% of patients. Fatal accidents cholera outbreaks have not been observed. Conclusion. Clinical diagnosis of cholera and the provision of medical care in the prehospital phase were poor, indicating the need for systematic conducting training seminars among experts of ambulance, as well as doctors of primary medical network. Cholera hospitals (or base hospitals) must be equipped with a mobile diagnostics (ultrasound, X-rays) and modern laboratory equipment. The required list of drug supply cholera hospitals should be expanded in view of possible complications and comorbidities