Three-loop corrections to the lightest Higgs scalar boson mass in supersymmetry

I evaluate the largest three-loop corrections to the mass of the lightest Higgs scalar boson in the Minimal Supersymmetric Standard Model in a mass-independent renormalization scheme, using effective field theory and renormalization group methods. The contributions found here are those that depend only on strong and Yukawa interactions and on the leading and next-to-leading logarithms of the ratio of a typical superpartner mass scale to the top quark mass. The approximation assumes that all superpartners and the other Higgs bosons can be treated as much heavier than the top quark, but does not assume their degeneracy. I also discuss the consistent addition of the three-loop corrections to a complete two-loop calculation.Comment: 9 page

Dynamical supersymmetry breaking in models with a Green-Schwarz mechanism

We consider supersymmetry breaking in theories with gaugino condensation in the presence of an anomalous U(1) symmetry with anomaly cancellation by the Green-Schwarz mechanism. In these models, a Fayet-Iliopoulos D-term can give important contributions to the soft supersymmetry-breaking scalar masses. Most discussions of this possibility have ignored the dilaton field. We argue that this is not appropriate in general, and show that the F-term contributions to the soft breaking terms are comparable to or much larger than the D-term contributions, depending on how the dilaton is stabilized. We discuss phenomenological implications of these results.Comment: 14 pages, LaTe

The Minimally Tuned Minimal Supersymmetric Standard Model

The regions in the Minimal Supersymmetric Standard Model with the minimal amount of fine-tuning of electroweak symmetry breaking are presented for general messenger scale. No a priori relations among the soft supersymmetry breaking parameters are assumed and fine-tuning is minimized with respect to all the important parameters which affect electroweak symmetry breaking. The superpartner spectra in the minimally tuned region of parameter space are quite distinctive with large stop mixing at the low scale and negative squark soft masses at the high scale. The minimal amount of tuning increases enormously for a Higgs mass beyond roughly 120 GeV.Comment: 38 pages, including 2 appendices, 8 figure

Strong and Yukawa two-loop contributions to Higgs scalar boson self-energies and pole masses in supersymmetry

I present results for the two-loop self-energy functions for neutral and charged Higgs scalar bosons in minimal supersymmetry. The contributions given here include all terms involving the QCD coupling, and those following from Feynman diagrams involving Yukawa couplings and scalar interactions that do not vanish as the electroweak gauge couplings are turned off. The impact of these contributions on the computation of pole masses of the neutral and charged Higgs scalar bosons is studied in a few examples.Comment: 23 pages, 9 figures, revtex4. New paragraph in introduction, more explanation of Figure

SEU Tests Performed on the Digital Communication System for LHC Cryogenic Instrumentation

The future LHC particle accelerator will use a large number of cryogenic sensors and actuators, most of which are located inside the machine tunnel and therefore in a radiation environment. These elements will communicate through a fieldbus. This paper reports the irradiation study carried out on WorldFIP fieldbus communication system. A digital communication system based on WorldFIP fieldbus protocol has been implemented and Single Event Effects (SEE) and Total Ionizing Dose (TID) radiation tests have been performed on it

Mobile Applications for Resting Tremor Assessment in Parkinson’s Disease: A Systematic Review

(1) Background: Resting tremor is a motor manifestation present in most Parkinson’s disease (PD) patients. For its assessment, several scales have been created, but mobile applications could help in objectively assessing resting tremor in PD patients in person and/or remotely in a more ecological scenario. (2) Methods: a systematic review following the PRISMA recommendations was conducted in scientific databases (PubMed, Medline, Science Direct, Academic Search Premier, and Web of Science) and in the main mobile application markets (Google Play, iOS App Store, and Windows Store) to determine the applications available for the assessment of resting tremor in patients with PD using only the measurement components of the phone itself (accelerometers and gyroscopes). (3) Results: 14 articles that used mobile apps to assess resting tremor in PD were included, and 13 apps were identified in the mobile application markets for the same purpose. The risk of bias and of applicability concerns of the articles analyzed was low. Mobile applications found in the app markets met an average of 85.09% of the recommendations for the development of medical mobile applications. (4) Conclusions: the use of mobile applications for the evaluation of resting tremor in PD patients has great potential, but validation studies for this purpose are scarce

Enhancement of "CP-odd" Higgs Boson Production in the Minimal Supersymmetric Standard Model with Explicit CP Violation

We calculate the production cross section of the ``CP-odd'' Higgs boson via gluon fusion in the minimal supersymmetric standard model with explicit CP violation in the stop sector. We show that there is a parameter region in which the cross section is enhanced by a factor of about 1000, as compared to the case without CP violation in the stop sector. In the parameter region where the ``CP-odd'' Higgs boson can decay into a stop pair, the stop pair events will be the important signature of the enhanced ``CP-odd'' Higgs boson. In the case where the ``CP-odd'' Higgs boson cannot decay into any superparticles, the gamma gamma and tau tau decay channels could become important for discovering the ``CP-odd'' Higgs boson. We also discuss the constraints from electric dipole moments of electron, neutron and mercury on the viable parameter space mentioned above.Comment: 13 pages, 3 figure

Neutralino Dark Matter in BMSSM Effective Theory

We study thermal neutralino dark matter in an effective field theory extension of the MSSM, called "Beyond the MSSM" (BMSSM) in Dine, Seiberg and Thomas (2007). In this class of effective field theories, the field content of the MSSM is unchanged, but the little hierarchy problem is alleviated by allowing small corrections to the Higgs/higgsino part of the Lagrangian. We perform parameter scans and compute the dark matter relic density. The light Higgsino LSP scenario is modified the most; we find new regions of parameter space compared to the standard MSSM. This involves interesting interplay between the WMAP dark matter bounds and the LEP chargino bound. We also find some changes for gaugino LSPs, partly due to annihilation through a Higgs resonance, and partly due to coannihilation with light stops in models that are ruled in by the new effective terms.Comment: 37 pages + appendi

Two-loop effective potential for a general renormalizable theory and softly broken supersymmetry

I compute the two-loop effective potential in the Landau gauge for a general renormalizable field theory in four dimensions. Results are presented for the \bar{MS} renormalization scheme based on dimensional regularization, and for the \bar{DR} and \bar{DR}' schemes based on regularization by dimensional reduction. The last of these is appropriate for models with softly broken supersymmetry, such as the Minimal Supersymmetric Standard Model. I find the parameter redefinition which relates the \bar{DR} and \bar{DR}' schemes at two-loop order. I also discuss the renormalization group invariance of the two-loop effective potential, and compute the anomalous dimensions for scalars and the beta function for the vacuum energy at two-loop order in softly broken supersymmetry. Several illustrative examples and consistency checks are included.Comment: 38 pages. Typos in equations (3.5), (3.11), and (6.3) are fixed. Explicit claim of renormalization group invariance in the general case of softly-broken supersymmetry is added. Additional discussion of cases of multiple simple or U(1) groups. Equations in Appendix B rewritten in a more useful for

Mobile phone text messaging to improve medication adherence in secondary prevention of cardiovascular disease.

BACKGROUND: Worldwide at least 100 million people are thought to have prevalent cardiovascular disease (CVD). This population has a five times greater chance of suffering a recurrent cardiovascular event than people without known CVD. Secondary CVD prevention is defined as action aimed to reduce the probability of recurrence of such events. Drug interventions have been shown to be cost-effective in reducing this risk and are recommended in international guidelines. However, adherence to recommended treatments remains sub-optimal. In order to influence non-adherence, there is a need to develop scalable and cost-effective behaviour-change interventions. OBJECTIVES: To assess the effects of mobile phone text messaging in patients with established arterial occlusive events on adherence to treatment, fatal and non-fatal cardiovascular events, and adverse effects. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, the Conference Proceedings Citation Index - Science on Web of Science on 7 November 2016, and two clinical trial registers on 12 November 2016. We contacted authors of included studies for missing information and searched reference lists of relevant papers. We applied no language or date restrictions. SELECTION CRITERIA: We included randomised trials with at least 50% of the participants with established arterial occlusive events. We included trials investigating interventions using short message service (SMS) or multimedia messaging service (MMS) with the aim to improve adherence to medication for the secondary prevention of cardiovascular events. Eligible comparators were no intervention or other modes of communication. DATA COLLECTION AND ANALYSIS: We used standard methodological procedures expected by Cochrane. In addition, we attempted to contact all authors on how the SMS were developed. MAIN RESULTS: We included seven trials (reported in 13 reports) with 1310 participants randomised. Follow-up ranged from one month to 12 months. Due to heterogeneity in the methods, population and outcome measures, we were unable to conduct meta-analysis on these studies. All seven studies reported on adherence, but using different methods and scales. Six out of seven trials showed a beneficial effect of mobile phone text messaging for medication adherence. Dale 2015a, reported significantly greater medication adherence score in the intervention group (Mean Difference (MD) 0.58, 95% confidence interval (CI) 0.19 to 0.97; 123 participants randomised) at six months. Khonsari 2015 reported less adherence in the control group (Relative Risk (RR) 4.09, 95% CI 1.82 to 9.18; 62 participants randomised) at eight weeks. Pandey 2014 (34 participants randomised) assessed medication adherence through self-reported logs with 90% adherence in the intervention group compared to 70% in the control group at 12 months. Park 2014a (90 participants randomised) reported a greater increase of the medication adherence score in the control group, but also measured adherence with an event monitoring system for a number of medications with adherence levels ranging from 84.1% adherence to 86.2% in the intervention group and 79.7% to 85.7% in the control group at 30 days. Quilici 2013, reported reduced odds of non-adherence in the intervention group (Odds Ratio (OR) 0.43, 95% CI 0.22 to 0.86, 521 participants randomised) at 30 days. Fang 2016, reported that participants given SMS alone had reduced odds of being non-adherent compared to telephone reminders (OR 0.40 95% CI 0.18 to 0.63; 280 patients randomised). Kamal 2015 reported higher levels of adherence in the intervention arm (adjusted MD 0.54, 95% CI 0.22 to 0.85; 200 participants randomised). Khonsari 2015 was the only study to report fatal cardiovascular events and only reported two events, both in the control arm. No study reported on the other primary outcomes. No study reported repetitive thumb injury or road traffic crashes or other adverse events that were related to the intervention.Four authors replied to our questionnaire on SMS development. No study reported examining causes of non-adherence or provided SMS tailored to individual patient characteristics.The included studies were small, heterogeneous and included participants recruited directly after acute events. All studies were assessed as having high risk of bias across at least one domain. Most of the studies came from high-income countries, with two studies conducted in an upper middle-income country (China, Malaysia), and one study from a lower middle-income country (Pakistan). The quality of the evidence was found to be very low. There was no obvious conflicts of interest from authors, although only two declared their funding. AUTHORS' CONCLUSIONS: While the results of this systematic review are promising, there is insufficient evidence to draw conclusions on the effectiveness of text message-based interventions for adherence to medications for secondary prevention of CVD. Sufficiently powered, high-quality randomised trials are needed, particularly in low- and middle-income countries