User Experience Design Manifesto

The rapid change of the elements of context requires an urgent reflection on "Experience" and "Meaning with Value". The aim of this article is to critically review the User Experience Design (UXD) as a disciplinary field, and contribute by a Manifesto to an inspiring vision of the future. Some authors will be reviewed in order to list and discuss the different ideas to redefine the desirable skills to an enlightened practice and to influence a new ethos of "Be Innovation" to a better world. The article retrieves and revisits a Design Manifesto made on the basis of a strategic vision for Design based on distinctive design competencies. This Manifesto was in the origin of the platform www.inspaedia.com.CITAD – Centro de Investigação em Território, Arquitetura e Design, Universidades de Lusíada, Portugal; CIAUD – Centro de Investigação em Arquitetura, Urbanismo e Design, Faculdade de Arquitetura, Universidade de Lisboa, Portugal. This research is financed by national funds from the FCT – Fundação para a Ciência e a Tecnologia, Portugal, within the scope of the project UID/AUR/04026/2013

Can mixed reality technologies teach surgical skills better than traditional methods? A prospective randomised feasibility study

Background Basic surgical skills teaching is often delivered with didactic audio-visual content, and new digital technologies may allow more engaging and effective ways of teaching to be developed. The Microsoft HoloLens 2 (HL2) is a multi-functional mixed reality headset. This prospective feasibility study sought to assess the device as a tool for enhancing technical surgical skills training. Methods A prospective randomised feasibility study was conducted. 36 novice medical students were trained to perform a basic arteriotomy and closure using a synthetic model. Participants were randomised to receive a structured surgical skills tutorial via a bespoke mixed reality HL2 tutorial (n = 18), or via a standard video-based tutorial (n = 18). Proficiency scores were assessed by blinded examiners using a validated objective scoring system and participant feedback collected. Results The HL2 group showed significantly greater improvement in overall technical proficiency compared to the video group (10.1 vs. 6.89, p = 0.0076), and a greater consistency in skill progression with a significantly narrower range of scores (SD 2.48 vs. 4.03, p = 0.026). Participant feedback showed the HL2 technology to be more interactive and engaging with minimal device related problems experienced. Conclusions This study has demonstrated that mixed reality technology may provide a higher quality educational experience, improved skill progression and greater consistency in learning when compared to traditional teaching methodologies for basic surgical skills. Further work is required to refine, translate, and evaluate the scalability and applicability of the technology across a broad range of skills-based disciplines

Getting it right: The case for supervisors assessing process in capstone projects

© 2015 TEMPUS Publications. Capstone projects represent the culmination of an undergraduate engineering degree and are typically the last checkpoint measure before students graduate and enter the engineering profession. In Australia there is a longstanding interest in and commitment to developing quality capstone experiences.Anational study into the supervision and assessment of capstone projects has determined that whilst there is relative consistency in terms of what project tasks are set and assessed, there is not comparable consistency in how these tasks or assignments are marked. Two interconnected areas of assessing process and the role of the supervisor in marking are identified as contentious. This paper presents some findings of a national case study and concludes that whilst further investigation is warranted, assessing process as well as project products is valuable as is the need for greater acceptance of project supervisors as capable of making informed, professional judgments when marking significant project work

Association of FCGR3A and FCGR3B haplotypes with rheumatoid arthritis and primary Sjögren's syndrome [POSTER PRESENTATION]

Background Rheumatoid arthritis (RA) is an autoimmune disease that is thought to arise from a complex interaction between multiple genetic factors and environmental triggers. We have previously demonstrated an association between a Fc gamma receptor (FcγR) haplotype and RA in a cross-sectional cohort of RA patients. We have sought to confirm this association in an inception cohort of RA patients and matched controls. We also extended our study to investigate a second autoanti-body associated rheumatic disease, primary Sjögren's syndrome (PSS). Methods The FCGR3A-158F/V and FCGR3B-NA1/NA2 functional polymorphisms were examined for association in an inception cohort of RA patients (n = 448), and a well-characterised PSS cohort (n = 83) from the United Kingdom. Pairwise disequilibrium coefficients (D') were calculated in 267 Blood Service healthy controls. The EHPlus program was used to estimate haplotype frequencies for patients and controls and to determine whether significant linkage disequilibrium was present. A likelihood ratio test is performed to test for differences between the haplotype frequencies in cases and controls. A permutation procedure implemented in this program enabled 1000 permutations to be performed on all haplotype associations to assess significance. Results There was significant linkage disequilibrium between FCGR3A and FCGR3B (D' = -0.445, P = 0.001). There was no significant difference in the FCGR3A or FCGR3B allele or genotype frequencies in the RA or PSS patients compared with controls. However, there was a significant difference in the FCGR3A-FCGR3B haplotype distributions with increased homozygosity for the FCGR3A-FCGR3B 158V-NA2 haplotype in both our inception RA cohort (odds ratio = 2.15, 95% confidence interval = 1.1–4.2 P = 0.027) and PSS (odds ratio = 2.83, 95% confidence interval = 1.0–8.2, P = 0.047) compared with controls. The reference group for these analyses comprised individuals who did not possess a copy of the FCGR3A-FCGR3B 158V-NA2 haplotype. Conclusions We have confirmed our original findings of association between the FCGR3A-FCGR3B 158V-NA2 haplotype and RA in a new inception cohort of RA patients. This suggests that there may be an RA-susceptibility gene at this locus. The significant increased frequency of an identical haplotype in PSS suggests the FcγR genetic locus may contribute to the pathogenesis of diverse autoantibody-mediated rheumatic diseases

The use of mixed reality technology for the objective assessment of clinical skills: a validation study

Background Mixed Reality technology may provide many advantages over traditional teaching methods. Despite its potential, the technology has yet to be used for the formal assessment of clinical competency. This study sought to collect validity evidence and assess the feasibility of using the HoloLens 2 mixed reality headset for the conduct and augmentation of Objective Structured Clinical Examinations (OSCEs). Methods A prospective cohort study was conducted to compare the assessment of undergraduate medical students undertaking OSCEs via HoloLens 2 live (HLL) and recorded (HLR), and gold-standard in-person (IP) methods. An augmented mixed reality scenario was also assessed. Results 13 undergraduate participants completed a total of 65 OSCE stations. Overall inter-modality correlation was 0.81 (p=0.01), 0.98 (p=0.01) and 0.82 (p=0.01) for IP vs. HLL, HLL vs. HLR and IP vs. HLR respectively. Skill based correlations for IP vs. HLR were assessed for history taking (0.82, p=0.01), clinical examination (0.81, p=0.01), procedural (0.88, p=0.01) and clinical skills (0.92, p=0.01), and assessment of a virtual mixed reality patient (0.74, p=0.01). The HoloLens device was deemed to be usable and practical (Standard Usability Scale (SUS) score = 51.5), and the technology was thought to deliver greater flexibility and convenience, and have the potential to expand and enhance assessment opportunities. Conclusions HoloLens 2 is comparable to traditional in-person examination of undergraduate medical students for both live and recorded assessments, and therefore is a valid and robust method for objectively assessing performance. The technology is in its infancy, and users need to develop confidence in its usability and reliability as an assessment tool. However, the potential to integrate additional functionality including holographic content, automated tracking and data analysis, and to facilitate remote assessment may allow the technology to enhance, expand and standardise examinations across a range of educational contexts

51 Eri and GJ 3305: A 10-15 Myr old binary star system at 30 parsecs

Following the suggestion of Zuckerman et al. (2001, ApJ, 562, L87), we consider the evidence that 51 Eri (spectral type F0) and GJ 3305 (M0), historically classified as unrelated main sequence stars in the solar neighborhood, are instead a wide physical binary system and members of the young beta Pic moving group (BPMG). The BPMG is the nearest (d < 50 pc) of several groups of young stars with ages around 10 Myr that are kinematically convergent with the Oph-Sco-Cen Association (OSCA), the nearest OB star association. Combining SAAO optical photometry, Hobby-Eberly Telescope high-resolution spectroscopy, Chandra X-ray data, and UCAC2 catalog kinematics, we confirm with high confidence that the system is indeed extremely young. GJ 3305 itself exhibits very strong magnetic activity but has rapidly depleted most of its lithium. The 51 Eri/GJ 3305 system is the westernmost known member of the OSCA, lying 110 pc from the main subgroups. The system is similar to the BPMG wide binary HD 172555/CD -64d1208 and the HD 104237 quintet, suggesting that dynamically fragile multiple systems can survive the turbulent environments of their natal giant molecular cloud complexes, while still being imparted high dispersion velocities. Nearby young systems such as these are excellent targets for evolved circumstellar disk and planetary studies, having stellar ages comparable to that of the late phases of planet formation.Comment: 27 pages, 7 figures. Accepted for publication in the Astronomical Journal. For a version with high resolution figures, see http://www.astro.psu.edu/users/edf/51Eri.pd

Stability of wheat grain yields over three field seasons in the UK

Ensuring food security in a changing climate is a major contemporary challenge and requires development of climate resilient crops that perform well under variable environments. The hypothesis that yield stability in sub-optimal conditions is linked to yield penalties in optimal conditions was investigated in field-grown wheat in the UK. The phenotypic responses, rate of wheat crop development and final grain yield, to varying sowing date, rainfall, air temperature and radiation patterns were studied for a panel of 61 elite commercial wheat cultivars grown in the UK in 2012, 2013 and 2014. Contrasting climatic patterns, particularly rainfall accumulation and distribution over the season, influenced the relative performance of the cultivars affecting the duration of grain development stage and impacting on productivity. Indices for crop productivity, yield stability and performance under sub-optimal conditions revealed four cultivars with a combination of stable and high relative grain yields over the three seasons: Gladiator, Humber, Mercato and Zebedee. Genetic similarity between cultivars partially explained yield performance in the contrasting seasons. The year of release of the cultivars correlated with grain yield but not with yield stability, supporting the contention that breeding for yield potential does not select for climate resilience and yield stability of crops. Further analysis of the outstanding cultivars may unravel target traits for breeding efforts aimed at increasing wheat yield potential and stability in the changing climate. This article is protected by copyright. All rights reserved

Generalized Kahler geometry and gerbes

We introduce and study the notion of a biholomorphic gerbe with connection. The biholomorphic gerbe provides a natural geometrical framework for generalized Kahler geometry in a manner analogous to the way a holomorphic line bundle is related to Kahler geometry. The relation between the gerbe and the generalized Kahler potential is discussed.Comment: 28 page