26 research outputs found

    Zur Führungsrolle des Grauen Bundes und der Stadt Ilanz in der frühen Reformbewegung Graubündens

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    Of the seven crucial reform decrees written between 1523 and 1526 in the three free states of Graubunden, five were issued in Ilanz, and two in Chur. Ilanz, the first and only Romansch speaking city on the Rhine was the center of the Grey League and fostered a close relationship to Zwingli’s Zurich as well as with southern Germany. A school of writing developed in this location, whilst the chancery of the Grey League maintained from here diplomatic correspondences throughout Europe. The scholarly clerics and politicians trained in humanism prepared the official decrees that led to the breakthrough of the Reformation

    1975年から2017年までにケニアでコレラのアウトブレイクを引き起こしたコレラ菌株の性状分析に関する研究

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    長崎大学学位論文 [学位記番号]博(医歯薬)乙第57号 [学位授与年月日]令和元年12月4

    Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant

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    Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%–50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). Furthermore, the D614G spike mutant dominates the pandemic and it is unclear how serological tests designed to detect anti-spike antibodies perform against this variant. We assess the diagnostic accuracy of combined rapid antibody point of care (POC) and nucleic acid assays for suspected COVID-19 disease due to either wild-type or the D614G spike mutant SARS-CoV-2. The overall detection rate for COVID-19 is 79.2% (95% CI 57.8–92.9) by rapid NAAT alone. The combined point of care antibody test and rapid NAAT is not affected by D614G and results in very high sensitivity for COVID-19 diagnosis with very high specificity

    The NUITM-KEMRI P3 Laboratory in Kenya: Establishment, Features, Operation and Maintenance

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    A biocontainment facility is a core component in any research setting due to the services it renders towards comprehensive biosafety observance. The NUITM-KEMRI P3 facility was set up in 2007 and has been actively in use since 2010 by researchers from this and other institutions. A number of hazardous agents have been handled in the laboratory among them MDR-TB and yellow fever viruses. The laboratory has the general physical and operational features of a P3 laboratory in addition to a number of unique features, among them the water-air filtration system, the eco-mode operation feature and automation of the pressure system that make the facility more efficient. It is equipped with biosafety and emergency response equipments alongside common laboratory equipments, maintained regularly using daily, monthly and yearly routines. Security and safety is strictly observed within the facility, enhanced by restricted entry, strict documentation and use of safety symbols. Training is also engrained within the operation of the laboratory and is undertaken and evaluated annually. Though the laboratory is in the process of obtaining accreditation, it is fully certified courtesy of the manufactures\u27 and constructed within specified standards
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