5,698 research outputs found
Trans-Planckian Dark Energy?
It has recently been proposed by Mersini et al. 01, Bastero-Gil and Mersini
02 that the dark energy could be attributed to the cosmological properties of a
scalar field with a non-standard dispersion relation that decreases
exponentially at wave-numbers larger than Planck scale (k_phys > M_Planck). In
this scenario, the energy density stored in the modes of trans-Planckian
wave-numbers but sub-Hubble frequencies produced by amplification of the vacuum
quantum fluctuations would account naturally for the dark energy. The present
article examines this model in detail and shows step by step that it does not
work. In particular, we show that this model cannot make definite predictions
since there is no well-defined vacuum state in the region of wave-numbers
considered, hence the initial data cannot be specified unambiguously. We also
show that for most choices of initial data this scenario implies the production
of a large amount of energy density (of order M_Planck^4) for modes with
momenta of order M_Planck, far in excess of the background energy density. We
evaluate the amount of fine-tuning in the initial data necessary to avoid this
back-reaction problem and find it is of order H/M_Planck. We also argue that
the equation of state of the trans-Planckian modes is not vacuum-like.
Therefore this model does not provide a suitable explanation for the dark
energy.Comment: RevTeX - 15 pages, 7 figures: final version to appear in PRD, minor
changes, 1 figure adde
VUV photo-processing of PAH cations: quantitative study on the ionization versus fragmentation processes
Interstellar polycyclic aromatic hydrocarbons (PAHs) are strongly affected by
the absorption of vacuum ultraviolet (VUV) photons in the interstellar medium
(ISM), yet the branching ratio between ionization and fragmentation is poorly
studied. This is crucial for the stability and charge state of PAHs in the ISM
in different environments, affecting in turn the chemistry, the energy balance,
and the contribution of PAHs to the extinction and emission curves. We studied
the interaction of PAH cations with VUV photons in the 7-20 eV range from the
synchrotron SOLEIL beamline, DESIRS. We recorded by action spectroscopy the
relative intensities of photo-fragmentation and photo-ionization for a set of
eight PAH cations ranging in size from 14 to 24 carbon atoms, with different
structures. At photon energies below ~13.6 eV fragmentation dominates for the
smaller species, while for larger species ionization is immediately competitive
after the second ionization potential (IP). At higher photon energies, all
species behave similarly, the ionization yield gradually increases, leveling
off between 0.8 and 0.9 at ~18 eV. Among isomers, PAH structure appears to
mainly affect the fragmentation cross section, but not the ionization cross
section. We also measured the second IP for all species and the third IP for
two of them, all are in good agreement with theoretical ones confirming that
PAH cations can be further ionized in the diffuse ISM. Determining actual PAH
dication abundances in the ISM will require detailed modeling. Our measured
photo-ionization yields for several PAH cations provide a necessary ingredient
for such models
Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus pneumoniae
BACKGROUND: The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when strains show additional resistance to quinolones. The main objective of this study was to determine a treatment modality impeding the emergence of quinolone resistance. RESULTS: Exposure of a penicillin-resistant pneumococcus to increasing concentrations of trovafloxacin or ciprofloxacin selected for mutants resistant to these drugs. In the presence of sub-inhibitory concentrations of vancomycin, development of trovafloxacin-resistance and high-level ciprofloxacin-resistance were prevented. CONCLUSIONS: Considering the risk of quinolone-resistance in pneumococci, the observation might be of clinical importance
Long Cycles in a Perturbed Mean Field Model of a Boson Gas
In this paper we give a precise mathematical formulation of the relation
between Bose condensation and long cycles and prove its validity for the
perturbed mean field model of a Bose gas. We decompose the total density
into the number density of
particles belonging to cycles of finite length () and to
infinitely long cycles () in the thermodynamic limit. For
this model we prove that when there is Bose condensation,
is different from zero and identical to the condensate density. This is
achieved through an application of the theory of large deviations. We discuss
the possible equivalence of with off-diagonal long
range order and winding paths that occur in the path integral representation of
the Bose gas.Comment: 10 page
WMAP data and the curvature of space
Inter alia, the high precision WMAP data on Cosmic Microwave Background
Radiation marginally indicate that the universe has positively curved (and
hence spherical) spatial sections. In this paper, we take this data seriously
and consider some of the consequences for the background dynamics. In
particular, we show that this implies a limit to the number of e-foldings that
could have taken place in the inflationary epoch; however this limit is
consistent with some inflationary models that solve all the usual cosmological
problems and are consistent with standard structure formation theory.Comment: 4 pages, 2 figure
TRIDENT: an Infrared Differential Imaging Camera Optimized for the Detection of Methanated Substellar Companions
A near-infrared camera in use at the Canada-France-Hawaii Telescope (CFHT)
and at the 1.6-m telescope of the Observatoire du Mont-Megantic is described.
The camera is based on a Hawaii-1 1024x1024 HgCdTe array detector. Its main
feature is to acquire three simultaneous images at three wavelengths across the
methane absorption bandhead at 1.6 microns, enabling, in theory, an accurate
subtraction of the stellar point spread function (PSF) and the detection of
faint close methanated companions. The instrument has no coronagraph and
features fast data acquisition, yielding high observing efficiency on bright
stars. The performance of the instrument is described, and it is illustrated by
laboratory tests and CFHT observations of the nearby stars GL526, Ups And and
Chi And. TRIDENT can detect (6 sigma) a methanated companion with delta H = 9.5
at 0.5" separation from the star in one hour of observing time. Non-common path
aberrations and amplitude modulation differences between the three optical
paths are likely to be the limiting factors preventing further PSF attenuation.
Instrument rotation and reference star subtraction improve the detection limit
by a factor of 2 and 4 respectively. A PSF noise attenuation model is presented
to estimate the non-common path wavefront difference effect on PSF subtraction
performance.Comment: 41 pages, 16 figures, accepted for publication in PAS
The stress-energy tensor for trans-Planckian cosmology
This article presents the derivation of the stress-energy tensor of a free
scalar field with a general non-linear dispersion relation in curved spacetime.
This dispersion relation is used as a phenomelogical description of the short
distance structure of spacetime following the conventional approach of
trans-Planckian modes in black hole physics and in cosmology. This
stress-energy tensor is then used to discuss both the equation of state of
trans-Planckian modes in cosmology and the magnitude of their backreaction
during inflation. It is shown that gravitational waves of trans-Planckian
momenta but subhorizon frequencies cannot account for the form of cosmic vacuum
energy density observed at present, contrary to a recent claim. The
backreaction effects during inflation are confirmed to be important and generic
for those dispersion relations that are liable to induce changes in the power
spectrum of metric fluctuations. Finally, it is shown that in pure de Sitter
inflation there is no modification of the power spectrum except for a possible
magnification of its overall amplitude independently of the dispersion
relation.Comment: 18 pages, 2 figures. Version to appear in PRD (minor modifications
Genome-wide transcriptional response of an avian pathogenic Escherichia coli (APEC) pst mutant
<p>Abstract</p> <p>Background</p> <p>Avian pathogenic <it>E</it>. <it>coli </it>(APEC) are associated with extraintestinal diseases in poultry. The <it>pstSCAB</it>-<it>phoU </it>operon belongs to the Pho regulon and encodes the phosphate specific transport (Pst) system. A functional Pst system is required for full virulence in APEC and other bacteria and contributes to resistance of APEC to serum, to cationic antimicrobial peptides and acid shock. The global mechanisms contributing to the attenuation and decreased resistance of the APEC <it>pst </it>mutant to environmental stresses have not been investigated at the transcriptional level. To determine the global effect of a <it>pst </it>mutation on gene expression, we compared the transcriptomes of APEC strain χ7122 and its isogenic <it>pst </it>mutant (K3) grown in phosphate-rich medium.</p> <p>Results</p> <p>Overall, 470 genes were differentially expressed by at least 1.5-fold. Interestingly, the <it>pst </it>mutant not only induced systems involved in phosphate acquisition and metabolism, despite phosphate availability, but also modulated stress response mechanisms. Indeed, transcriptional changes in genes associated with the general stress responses, including the oxidative stress response were among the major differences observed. Accordingly, the K3 strain was less resistant to reactive oxygen species (ROS) than the wild-type strain. In addition, the <it>pst </it>mutant demonstrated reduced expression of genes involved in lipopolysaccharide modifications and coding for cell surface components such as type 1 and F9 fimbriae. Phenotypic tests also established that the <it>pst </it>mutant was impaired in its capacity to produce type 1 fimbriae, as demonstrated by western blotting and agglutination of yeast cells, when compared to wild-type APEC strain χ7122.</p> <p>Conclusion</p> <p>Overall, our data elucidated the effects of a <it>pst </it>mutation on the transcriptional response, and further support the role of the Pho regulon as part of a complex network contributing to phosphate homeostasis, adaptive stress responses, and <it>E. coli </it>virulence.</p
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