Physical activity is associated with improved mathematical computation, language reasoning, behavior and attention in ADHD girls

En la actualidad encontramos cifras alarmantes de sedentarismo e inactividad física, doscondiciones que se asocian signifi-cativamente con el cálculo matemático, razonamiento lingüístico, comportamiento y atenciónen edad escolar. Sin embargo, son escasos los estudios realizados en población escolar con Trastorno por Déficit de Atención e Hiperactividad (TDAH). El objetivo del presente estudio fue analizar la asociación del nivel de práctica de Actividad FísicaModerada-Vigorosa (AFMV) de escolaresdiagnosticadosTDAH con el cálculo matemático, el razonamiento lingüístico, el comportamiento hiperactivo-desatento y el nivel de atención selec-tiva. Participaron 94 estudiantes (44 chicos; 47% y 50 chicas; 53%) de 9.48 ± 2.10 años. El cálculo matemático y razonamiento lingüístico se evaluaron mediante test ad hoc. Para el comportamiento hiperactivo-desatento en el aula se utilizó la prueba EDAH y la atención se midió con el test d2.Los resultados mostraron que unamayorpráctica de AFMVse asocia con un mayor nivel de razona-miento lingüístico. Al realizar los análisis separando por sexo, en chicas, una mayor práctica de AFMV se asoció con un mayorcálculo matemático y razonamiento lingüístico, menor presencia de comportamiento hiperactivo-desatento y mejor nivel de atención. Se con-cluye queun alto nivel de AFMV semanalpodría predecir mayor cálculo matemático y razonamiento lingüísticoybaja presencia decomportamiento hiperactivo-impulsivo en el centro escolar. Los resultados sugieren el fomento de práctica de AFMV en escolares diagnosticados TDAHCurrently we find alarming figures for sedentary lifestyles and physical inactivity, two conditions that are significantly asso-ciated with mathematical calculation, linguistic reasoning, behaviour and attention at school age. However, few studies have beenconducted in school children with Attention Deficit Hyperactivity Disorder (ADHD). The aim of the present study was to analyse the association between the level of Moderate-Vigorous Physical Activity (MVPA) practice in schoolchildren diagnosed with ADHD and mathematical calculation, linguistic reasoning, hyperactive-attentive behaviour and the level of selective attention. Ninety-four students (44 boys; 47% and 50 girls; 53%) aged 9.48 ± 2.10 years participated. Mathematical calculation and linguistic reasoning were assessed by means of ad hoc tests. For hyperactive-attentive behaviour in the classroom the EDAH test was used and attention was measured with the d2 test. The results showed that a higher level of MVPA was associated with a higher level of linguistic reasoning. When analysed by gender, in girls, a higher level of MVPA was associated with higher mathematical calculation and linguistic reasoning, less hyperactive-attentive behaviour and a better level of attention. It is concluded that ahigh level of weekly MVPA could predict higher mathematical calculation and linguistic reasoning and low presence of hyperactive-impulsive behaviour at school. The results suggest the promotion of MVPA practice in schoolchildren diagnosed with ADH

Microbial uptake in oral mucosa-draining lymph nodes leads to rapid release of cytotoxic CD8+ T cells lacking a gut-homing phenotype.

The gastrointestinal (GI) tract constitutes an essential barrier against ingested microbes, including potential pathogens. Although immune reactions are well studied in the lower GI tract, it remains unclear how adaptive immune responses are initiated during microbial challenge of the oral mucosa (OM), the primary site of microbial encounter in the upper GI tract. Here, we identify mandibular lymph nodes (mandLNs) as sentinel lymphoid organs that intercept ingested Listeria monocytogenes (Lm). Oral Lm uptake led to local activation and release of antigen-specific CD8+ T cells that constituted most of the early circulating effector T cell (TEFF) pool. MandLN-primed TEFF disseminated to lymphoid organs, lung, and OM and contributed substantially to rapid elimination of target cells. In contrast to CD8+ TEFF generated in mesenteric LN (MLN) during intragastric infection, mandLN-primed TEFF lacked a gut-seeking phenotype, which correlated with low expression of enzymes required for gut-homing imprinting by mandLN stromal and dendritic cells. Accordingly, mandLN-primed TEFF decreased Lm burden in spleen but not MLN after intestinal infection. Our findings extend the concept of regional specialization of immune responses along the length of the GI tract, with CD8+ TEFF generated in the upper GI tract displaying homing profiles that differ from those imprinted by lymphoid tissue of the lower GI tract

Revista Temas Agrarios Volumen 26; Suplemento 1 de 2021

1st International and 2nd National Symposium of Agronomic Sciences: The rebirth of the scientific discussion space for the Colombian Agro.1 Simposio Intenacional y 2 Nacional de Ciencias Agronómicas: El renacer del espacio de discusión científica para el Agro colombiano