8 research outputs found
PP-239 Ancylostoma spp. in soil of public recreative areas of Culiacan and Navolato Sinaloa, Mexico
- Author
- Publication venue
- Elsevier Ltd.
- Publication date
- 31/07/2010
- Field of study
Colelitiasis y colecistectomĂa en pacientes con insuficiencia renal crĂłnica
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
PP-243 Giardia in soil of public parks of Culiacan, Sinaloa, Mexico
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Evaluation of predation of the mite Lasioseius penicilliger
- Author
- Publication venue
- 'Cambridge University Press (CUP)'
- Publication date
- Field of study
Cross-cultural validation and measurement invariance of anxiety and depression symptoms: A study of the Brief Symptom Inventory (BSI) in 42 countries.
- Author
- Ballester-Arnal R.
- BatthyĂĄny D.
- Bergeron S.
- Billieux J.
- Briken P.
- Burkauskas J.
- BĆthe B.
- Carvalho J.
- Castro-Calvo J.
- Chen L.
- Ciocca G.
- Corazza O.
- Csako R.I.
- CĂĄrdenas-LĂłpez G.
- Demetrovics Z.
- Escudero-Pastén J.I.
- Fernandez D.P.
- Fernandez E.F.
- Fujiwara H.
- Fuss J.
- GabrhelĂk R.
- Gewirtz-Meydan A.
- Gjoneska B.
- Gola M.
- Grubbs J.B.
- Hashim H.T.
- Islam M.S.
- Ismail M.
- JimĂ©nez-MartĂnez M.C.
- Jurin T.
- Kalina O.
- Klein V.
- KoĂłs M.
- Kraus S.W.
- KöltĆ A.
- Lee C.T.
- Lee S.K.
- Lewczuk K.
- Lin C.Y.
- Lochner C.
- LukavskĂĄ K.
- LĂłpez-Alvarado S.
- Mayta-TristĂĄn P.
- Miller D.J.
- Nagy L.
- OrosovĂĄ O.
- Orosz G.
- Ponce F.P.
- Potenza M.N.
- Quintana G.R.
- Quintero Garzola G.C.
- Ramos-Diaz J.
- Rigaud K.
- Rousseau A.
- Santibåñez-Palma J.F.
- Scanavino M.T.
- Schulmeyer M.K.
- Sharan P.
- Shibata M.
- Shoib S.
- Sigre-LeirĂłs V.
- Sniewski L.
- Spasovski O.
- Steibliene V.
- Stein D.J.
- Vaillancourt-Morel M.P.
- Van Hout M.C.
- Ănsal B.C.
- Publication venue
- Publication date
- Field of study
Depression and anxiety are among the most prevalent mental health issues experienced worldwide. However, whereas cross-cultural studies utilize psychometrically valid and reliable scales, fewer can meaningfully compare these conditions across different groups. To address this gap, the current study aimed to psychometrically assess the Brief Symptomatology Index (BSI) in 42 countries.
Using data from the International Sex Survey (NâŻ=âŻ82,243; M <sub>age</sub> âŻ=âŻ32.39; SD <sub>age</sub> âŻ=âŻ12.52; women: nâŻ=âŻ46,874; 57âŻ%), we examined the reliability of depression and anxiety symptom scores of the BSI-18, as well as evaluated evidence of construct, invariance, and criterion-related validity in predicting clinically relevant variables across countries, languages, genders, and sexual orientations.
Results corroborated an invariant, two-factor structure across all groups tested, exhibiting excellent reliability estimates for both subscales. The 'caseness' criterion effectively discriminated among those at low and high risk of depression and anxiety, yielding differential effects on the clinical criteria examined.
The predictive validation was not made against a clinical diagnosis, and the full BSI-18 scale was not examined (excluding the somatization sub-dimension), limiting the validation scope of the BSI-18. Finally, the study was conducted online, mainly by advertisements through social media, ultimately skewing our sample towards women, younger, and highly educated populations.
The results support that the BSI-12 is a valid and reliable assessment tool for assessing depression and anxiety symptoms across countries, languages, genders, and sexual orientations. Further, its caseness criterion can discriminate well between participants at high and low risk of depression and anxiety
Global urban environmental change drives adaptation in white clover
- Author
- Aguirre W.E.
- Akinwole P.O.
- Alberti M.
- Anderson J.J.
- Anderson J.T.
- Ando Y.
- Andrew N.R.
- Angeoletto F.
- Anstett D.N.
- Anstett J.
- Aoki-Gonçalves F.
- Arietta A.Z.A.
- Arroyo M.T.K.
- Austen E.J.
- Baena-DĂaz F.
- Barker C.A.
- Baylis H.A.
- Beliz J.M.
- Benitez-Mora A.
- Bickford D.
- Biedebach G.
- Blackburn G.S.
- Boehm M.M.A.
- Bonser S.P.
- Bonte D.
- Bragger J.R.
- Branquinho C.
- Brans K.I.
- Bresciano J.C.
- Brom P.D.
- Bucharova A.
- Burt B.
- Cahill J.F.
- Campbell K.D.
- Carlen E.J.
- Carmona D.
- Castellanos M.C.
- Centenaro G.
- Chalen I.
- Chaves J.A.
- Chen X-Y
- Chilton A.M.
- Chomiak K.M.
- ChĂĄvez-Pesqueira M.
- Cisneros-Heredia D.F.
- Cisse I.K.
- Classen A.T.
- Cohan B.
- Comerford M.S.
- Corney H.
- Crawford A.J.
- Crawford K.M.
- Dahirel M.
- David S.
- De Haan R.
- Deacon N.J.
- Dean C.
- del-Val E.
- Deligiannis E.K.
- Denney D.
- Dettlaff M.A.
- DiLeo M.F.
- Ding Y-Y
- Dominoni D.M.
- DomĂnguez-LĂłpez M.E.
- Draud S.L.
- Dyson K.
- Ellers J.
- Espinosa C.I.
- Essi L.
- Falahati-Anbaran M.
- FalcĂŁo J.C.F.
- Fargo H.T.
- Fellowes M.D.E.
- Fitzpatrick C.R.
- Fitzpatrick R.M.
- Flaherty L.E.
- Flood P. J.
- Flores M.F.
- Fornoni J.
- Foster A.G.
- Fradinger C.C.
- Frost C.J.
- Fuentes T.L.
- Fulkerson J.R.
- Gagnon E.
- Garbsch F.
- Garroway C.J.
- Gerstein A.C.
- Giasson M.M.
- Girdler E.B.
- Gkelis S.
- Godsoe W.
- Golemiec A.M.
- Golemiec M.
- GonzĂĄlez-Lagos C.
- Gorton A.J.
- Gotanda K.M.
- Granath G.
- Greiner S.
- Griffiths J.S.
- Grilo F.
- Gundel P.E.
- Hamilton B.
- Hardin J.M.
- He T.
- Heard S.B.
- Henriques A.F.
- HernĂĄndez-Poveda M.
- Hetherington-Rauth M.C.
- Hill S.J.
- Hochuli D.F.
- Hodgins K.A.
- Hood G.R.
- Hopkins G.R.
- Hovanes K.A.
- Howard A.R.
- Hubbard S.C.
- Ibarra-Cerdeña C.N.
- Innes S.G.
- Iñiguez-Armijos C.
- Jara-Arancio P.
- Jarrett B.J.M.
- Jeannot M.
- Jiménez-Lobato V.
- Johnson M.
- Johnson M.T.J.
- Johnson O.
- Johnson P.P.
- Johnson R.
- Josephson M.P.
- Jung M.C.
- Just M.G.
- Kahilainen A.
- Kailing O.S.
- Kariñho-Betancourt E.
- Karousou R.
- Kirn L.A.
- Kirschbaum A.
- Koch S.
- Laine A-L
- LaMontagne J.M.
- Lampei C.
- Lara C.
- Larson E.L.
- Le J.H.
- Leandro D.S.
- Lee C.
- Lei Y.
- Lequerica Tamara M.E.
- Levesque D.C.
- LeĂłn C.A.
- Liao W-J
- Ljubotina M.
- Locke H.
- Lockett M.T.
- Longo T.C.
- Lundholm J.T.
- LĂĄzaro-Lobo A.
- MacGillavry T.
- Mackin C.R.
- Mahmoud A.R.
- Manju I.A.
- Mariën J.
- MartĂnez D.N.
- MartĂnez-BartolomĂ© M.
- Meineke E.K.
- Mendoza-Arroyo W.
- Merritt L.E.L.
- Merritt T. J.S.
- Migiani G.
- Miles L.S.
- Minor E.S.
- Mitchell N.
- Mohammadi Bazargani M.
- Moles A.T.
- Monk J.D.
- Moore C.M.
- Morales-Morales P.A.
- Moyers B.T.
- Munim S.
- Munshi-South J.
- Murphy S.M.
- MurĂșa M.M.
- Muñoz-Rojas M.
- Neila M.
- Ness R.W.
- Nikolaidis O.
- NjunjiÄ I.
- Nosko P.
- NĂșñez-FarfĂĄn J.
- Ohgushi T.
- Olsen K.M.
- Opedal Ă.H.
- Ornelas C.
- Parachnowitsch A.L.
- Paratore A.S.
- Parody-Merino A.M.
- Paule J.
- Paulo O.S.
- Pena J.C.
- Peres-Neto P.R.
- Pfeiffer V.W.
- Pinho P.
- Piot A.
- Porth I.M.
- Poulos N.
- Prashad C.
- Puentes A.
- Qu J.
- Quintero-Vallejo E.
- Raciti S.M.
- Raeymaekers J.A.M.
- Raveala K.M.
- Rennison D.J.
- Ribeiro M.C.
- Richardson J.L.
- Rivas-Torres G.
- Rivera B. J.
- Roddy A.B.
- Rodriguez-Muñoz E.
- RomĂĄn J.R.
- Rossi L.S.
- Rowntree J.K.
- Ryan T.J.
- Salinas S.
- Sanders N.J.
- Santangelo J.S.
- Santiago-Rosario L.Y.
- Savage A.M.
- Scheepens J.F.
- Schilthuizen M.
- Schneider A.C.
- Scholier T.
- Scott J.L.
- Shaheed S.A.
- Shefferson R.P.
- Shepard C.A.
- Shykoff J.A.
- Silveira G.
- Smith A.D.
- Solis-Gabriel L.
- Soro A.
- Spellman K.V.
- Starke-Ottich I.
- Stephan J.G.
- Stephens J.D.
- Szulc J.
- Szulkin M.
- Tack A.J.M.
- Tamburrino Ă.
- Tate T.D.
- Tergemina E.
- Theodorou P.
- Thompson K.A.
- Threlfall C.G.
- Tinghitella R.M.
- Toledo-Chelala L.
- Tong A.T.
- Tong X.
- Uroy L.
- Utsumi S.
- Vandegehuchte M.L.
- VanWallendael A.
- Vidal P.M.
- Wadgymar S.M.
- Wang A-Y
- Wang N.
- Warbrick M.L.
- Whitney K.D.
- Whitney K.S.
- Wiesmeier M.
- Wiles J.T.
- Wu J.
- Xirocostas Z.A.
- Yan Z.
- Yao J.
- Yoder J.B.
- Yoshida O.
- Zhang J.
- Zhao Z.
- Ziter C.D.
- Zuellig M.P.
- Zufall R.A.
- Zurita J.E.
- Zytynska S.E.
- Ălvarez J.
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2022
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study
- Author
- Abe T.
- Aboshady Abdelrhman
- Abrough Fekri
- Acampo-de Jong Melanie J.
- Acharya S.
- Acharya Subhash P.
- Adderley Jane
- Adiguzel N.
- Agrawal V.K.
- Aguilar G.
- Aguirre Gaston
- Aguirre-Bermeo HernĂĄn
- Ahlström B.
- Akbas TĂŒrkay
- Akker M.
- Al Sadeh G.
- Alamri S.
- Algaba Ăngela
- Ali M.
- Aliberti A.
- Allegue J.M.
- Alvarez Diana
- Amador J.
- Amin P.
- Andersen F.H.
- Ansari S.
- Apichatbutr Yutthana
- Apostolopoulou Olympia
- Arabi Y.
- Aragao Irene CĂ©sar
- Arellano D.
- Arica Mestanza
- Arikan Huseyin
- Arinaga K.
- Arnal J.-M.
- Asano Kengo
- AsĂn-Corrochano M.
- Avalos Cabrera J.M.
- Avila Fuentes S.
- Aydemir Semih
- Aygencel Gulbin
- Azevedo L.
- Bacakoglu Feza
- Badie Julio C.
- Baedorf Kassis E.
- Bai Gabriela
- Balaraj Govindan
- Ballico B.
- Banner-Goodspeed Valerie M.
- Banwarie Preveen
- Barbieri R.
- Baronia Arvind Kumar
- Barrett Jonathan A.
- Barrot L.
- Barrueco-Francioni Jesus Emilio
- Barry Jeffrey
- Bauer Philippe R.
- Bawangade H.
- Beavis Sarah
- Beck E.
- Beduneau G.
- Beehre N.
- Beitler J.
- Belenguer Muncharaz Alberto
- Bellani Giacomo
- Belliato M.
- Bellissima A.
- Beltramelli Rodrigo
- Ben Souissi Asma
- Benitez-Cano A.
- Benlamin Mohamed
- Benslama Abdellatif
- Bento LuĂs Ă.
- Benvenuti Daniela
- Berkius J.
- Bernabe Laura
- Bersten Andrew D.
- Berta G.
- Bertini P.
- Bertram-Ralph Elliott
- Besbes M.
- Bettini L.R.
- Beuret P.
- Bewley Jeremy S.
- Bezzi M.
- Bhakhtiani L.
- Bhandary R.
- Bhowmick Kaushik
- Bihari S.
- Bissett B.
- Blythe D.
- Bocher Simon
- Boedjawan N.
- Bojanowski C.M.
- Boni E.
- Boraso Sabrina
- Borelli M.
- Borello S.
- Borislavova M.
- Bosma Karen J.
- Bottiroli M. A.
- Boyd Owen F.
- Bozbay S.
- Briva A.
- Brochard L.
- Bruel C.
- Bruni Andrea
- Buehner Ulrike
- Bugedo G.
- Bulpa P.
- Burt Karen
- Buscot Matthieu
- Buttera S.
- Cabrera Jorge
- Caccese Roberta
- Caironi P.
- Camporota Luigi
- Canchos Gutierrez Ivan
- Canedo N.
- Cani A.
- Cappellini I.
- Carazo Jesus
- Cardonnet Luis Pablo
- Carpio D.
- Carriedo Demetrio
- Carrillo RamĂłn
- Carvalho J.
- Caser Eliana Bernardete
- Castelli A.
- Castillo Quintero M.
- Castro H.
- Catorze Nuno T.
- Cengiz Melike
- Cereijo E.
- Cerny V.
- Ceunen H.
- Chaintoutis Christos
- Chang Youjin
- Chaparro G.
- Chapman Carmel
- Chau Simon K.
- Chavez C.E.
- Chelazzi Cosimo
- Chelly J.
- Chemouni F.
- Chen Kai
- Chena Ariel
- Chiarandini P.
- Chilton Phil
- Chiumello D.
- Cho Y.-J.
- Chou-Lie Y.
- Chudeau N.
- Cinel İsmail Hakkı
- Cinnella G.
- Clark Michele
- Clark Thomas
- Clarkson Kevin P.
- Clementi S.
- Coaguila Luis
- Codecido Alexis Jaspe
- Collins A.
- Colombo R.
- Conde Juan
- Consales G.
- Cook T.
- Coppadoro A.
- Cornejo Rodrigo A.
- Cortegiani Andrea
- Coxo Cristina M.
- Cracchiolo Andrea Neville
- Crespo Ramirez M.
- Crova P.
- Cruz José David
- Cubattoli L.
- Curto F.
- Czempik Piotr Filip
- d'Andrea R.
- da Silva Ramos F.
- Dangers L.
- Danguy Des DĂ©serts Marc
- Danin P.-E.
- Dantas F.
- Daubin CĂ©dric
- Dawei Wu
- de Haro C.
- de Jesus Montelongo Felipe
- de Mendoza Diego
- de Pablo RaĂșl
- de Pascale Gennaro D.
- de Rosa Silvia
- DecavĂšle Maxens
- Declercq P.-L.
- Deicas Alberto
- del Carmen Campos Moreno M.
- Dellamonica J.
- Delmas B.
- Demirkiran Hilmi
- Demirkiran Oktay
- Dendane T.
- Di Mussi Rosa
- Diakaki C.
- Diaz A.
- Diaz W.
- Dikmen Yalim
- Dimoula Aikaterini
- Doble P.
- Doha Nagwa M.
- Domingos G.
- Dres M.
- Dries D.
- Duggal Abhijit
- Duke Graeme J.
- Dunts Pavel V.
- Dybwik Knut
- Dykyy M.
- Eckert Philippe
- Efe Serdar
- Elatrous S.
- Elay GĂŒlseren
- Elmaryul Abubaker S.
- Elsaadany M.
- Elsayed Hany
- Elsayed Samar
- Emery M.
- Ena S.
- Eng Kevin
- Englert Joshua A.
- Erdogan E.
- Ergin Ozcan P.
- Eroglu Ege
- Escobar M.
- Esen Tekeli Arzu
- Esen F.
- Esquivel Gallegos H.
- Esquivel Alejandro
- Estenssoro Elisa
- Ezzouine H.
- Facchini Alberto
- Faheem Mohammad
- Fanelli V.
- Farina Maria Fernanda
- Fartoukh Muriel Sarah
- Fehrle Lutz
- Feng Feng
- Feng Yufeng
- Fernandez B.
- Fernandez Irene
- Fernandez-Rodriguez M.L.
- Ferrando Carlos
- Ferreira da Silva Maria JoĂŁo
- Ferreruela Mireia
- Ferrier Janet
- Flamm Zamorano Matias JesĂșs
- Flood Laura
- Floris L.
- Fluckiger M.
- Forteza Catalina
- Fortunato A.
- Frans E.
- Frattari A.
- Fredes SebastiĂĄn
- Frenzel Tim
- Fumagalli R.
- Furche M.A.
- Fusari Maurizio
- Fysh E.
- Galeas-Lopez J.L.
- Galerneau L.-M.
- Garcia Olivares P.
- Garcia AnalĂa
- Garcia E.
- Garcia M.F.
- Garlicki JarosĆaw B.
- Garnero Aude
- Garofalo E.
- Gautam Prabha
- Gazenkampf A.
- Gelinotte S.
- Gelormini Domenico
- Ghrenassia Ătienne
- Giacomucci Angelo
- Giannoni Roberto
- Gigante A.
- Glober Nancy King
- Gnesin Paolo
- Goligher E.
- Goligher E.C.
- Gollo Y.
- Gomaa Dina
- Gomero Paredes Rosita
- Gomes R.
- Gomez A.
- Gomez Oscar
- Gomez RaĂșl Alejandro
- Gondim Louise Aline RomĂŁo
- Gonzalez I.
- Gonzalez Manuel E.
- Gonzalez-Castro A.
- Gordillo Romero Orlando
- Gordo Federico
- Gouin Philippe
- Graf Santos J.
- Grainne R.
- Grando Matilde
- Granov Grabovica S.
- Grasselli Giacomo
- Grasso R.
- Grasso S.
- Grimmer Lisa
- Grissom Colin K.
- Gritsan Alexey I.
- Gu Qing
- Guan X.-D.
- Guarracino F.
- Guasch N.
- Guatteri Luca
- Gueret Renaud M.
- Guerot Emmanuel
- Guitard P.-G.
- Gumus Ayça
- Gurjar M.
- Gutierrez Patricia
- Guérin Claude
- GĂŒl Fethi
- Hachimi Abdelhamid
- Hadzibegovic A.
- Hagan Samantha J.
- Hammel Clare
- Han Song J.
- Hanlon Gabrielle C.
- Hashemian Seyed Mohammad Reza
- Heines Serge J.H.Jan Hubert
- Henriksson J.
- Herbrecht Jean Ătienne
- Heredia Orbegoso G.O.
- Hermans Greet M.
- Hermon A.
- Hernandez C.
- Hernandez R.
- Herrera Luis
- Herrera-Gutierrez M.
- Heunks Leo M.A.
- Heunks Leo M.A.
- Hidalgo J.
- Hill Dianne
- Holmquist D.
- Homez M.
- Hongtao Xia
- Hormis Anil P.
- Horner D.
- Hornos Micaela Carmen
- Hou M.
- House S.
- Housni B.
- Hugill Keith
- Humbert L.
- Humphreys Sally K.
- Hunter Stephanie
- Hwa Young Lee
- Iezzi N.
- Ilutovich Santiago
- Inal V.
- Innes R.
- Ioannides Panagiotis
- Iotti Giorgio Antonio
- Ippolito Mariachiara
- Irie Hiromasa
- Iriyama H.
- Itagaki T.
- Izura Javier J.
- Izza Santiago
- Jabeen R.
- Jamaati Hamidreza
- Jamadarkhana Sunil
- Jamoussi Amira
- Jankowski Milosz
- Jaramillo L.A.
- Jeon K.
- Jeong Lee Seok
- Jeswani Deepak
- Jha S.
- Jiang Liangyan
- Jing C.
- Jochmans S.
- Johnstad B.A.
- Jongmin Jongmin
- Joret A.
- Jovanovic B.
- Junhasavasdikul D.
- Jurado Maria Teresa
- Kam E.
- Kamohara H.
- Kane C.
- Kara Iskender
- Karakurt Sait
- Karnjanarachata C.
- Kataoka Jun
- Katayama Shinshu
- Kaushik S.
- Kelebek Girgin Nermin
- Kerr Kathryn
- Kerslake I.
- Khairnar Prakash
- Khalid Abidi
- Khan A.
- Khanna A.K.
- Khorasanee Reza
- Kienhorst Dieneke
- Kirakli C.
- Knafelj Rihard
- Kol Mark R.
- Kongpolprom N.
- Kopitko Csaba
- Korkmaz Ekren P.
- Kubisz-Pudelko A.
- Kulcsar Z.
- Kumasawa Junji
- Kurahashi Kiyoyasu
- Kuriyama Akira
- Kutchak F.
- Laake J.H.
- Labarca Eduardo F.
- Labat F.
- Laborda C.
- Laca Barrera M.A.
- Laffey J.G.
- Lagache Laurie
- Landaverde Lopez Antonio
- Lanspa M.
- Lascari Valeria
- Le Meur M.
- Lee J.
- Lee Jinwoo
- Lee S.H.
- Lee W.-Y.
- Lee Y.J.
- Legernaes T.
- Leiner Tamaas
- Lemiale Virginie
- Leonor T.
- Lepper Philipp Moritz
- Li D.
- Li H.
- Li O.
- Lima Ana Raquel
- Lind D.
- Litton E.
- Liu Jialin
- Liu Ling
- Liu N.
- Llitjos J.-F.
- Llorente Beatriz
- Lopez Nava C.
- Lopez C.E.
- Lopez R.
- Lovazzano Pablo
- Lu M.
- Lucchese F.
- Lugano M.
- Lugo Goytia Gustavo
- Luo H.
- Lynch C.
- Macheda Sebastiano
- Madotto F.
- Madrigal Robles V.H.
- Maggiore S.M.
- Magret Iglesias M.
- Malaga P.
- Mallapura Maheswarappa Harish
- Malpartida G.
- Malyarchikov A.
- Mancebo J.
- Mansson Helena Holm
- Manzano Anaid
- Marey I.
- Marin MarĂa
- Marin N.
- Markman E.
- Martin Dal Gesso Cristina
- Martin Alex
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- Yoshido Hector Higo Leon
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- Yun Xie
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- Zakalik G.
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- Zalba-Etayo Begoña
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- Zhang Guoxiu
- Zhang Hongwen
- Zhang Jiuzhi
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- Zhang Weixin
- Zhao H.
- Zheng Jia
- Zhu Bin
- Zumaran R.
- Ăukurova Z.
- Ăveges NĂĄndo
- Publication venue
- Elsevier
- Publication date
- 01/01/2023
- Field of study
International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0â4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (â€1 day), 457 (10·1%) had intermediate weaning (2â6 days), 433 (9·6%) required prolonged weaning (â„7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
Multi-messenger Observations of a Binary Neutron Star Merger
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- Yoshida M.
- Yoshida S.
- Yoshii T.
- Young D.R.
- Younk P.W.
- Yu Hang
- Yu Haocun
- Yu P.C.
- Yuan T.
- Yuan X.
- Yurkov V.V.
- Yushkov A.
- Yvert M.
- Zaborov D.
- Zacharias M.
- ZadroĆŒny A.
- ZadroĆŒny A.
- Zaharijas G.
- Zaltzman M.
- Zanin R.
- Zanolin M.
- Zaremba M.
- Zas E.
- Zavrtanik D.
- Zavrtanik M.
- Zdziarski A.A.
- Zech A.
- Zefi F.
- Zelenova T.
- Zendri J.P.
- Zenko T.
- Zenteno A.
- Zepeda A.
- Zertuche L.Maga
- Zevin M.
- Zhang A.M.
- Zhang B.B.
- Zhang C.
- Zhang C.L.
- Zhang C.M.
- Zhang F.
- Zhang H.
- Zhang H.M.
- Zhang J.
- Zhang L.
- Zhang M.
- Zhang Q.
- Zhang S.
- Zhang S.N.
- Zhang T.
- Zhang T.
- Zhang W.
- Zhang W.C.
- Zhang W.Z.
- Zhang Y.
- Zhang Y.
- Zhang Y.
- Zhang Y.F.
- Zhang Y.H.
- Zhang Y.J.
- Zhang Z.
- Zhang Z.L.
- Zhao C.
- Zhao H.S.
- Zhao J.L.
- Zhao W.
- Zhao X.F.
- Zheng S.J.
- Zhou H.
- Zhou J.
- Zhou M.
- Zhou Z.
- Zhu S.J.
- Zhu X.J.
- Zhu Y.
- Zhu Y.X.
- Zhu Z.
- Ziegler A.
- Zimmerman A.B.
- Zimmermann B.
- Zimnukhov D.S.
- Ziolkowski M.
- Zoll M.
- Zong Z.
- Zorn J.
- Zornoza J.D.
- Zou C.L.
- Zuccarello F.
- Zucker M.E.
- Zweizig J.
- ZĂșñiga J.
- Ălvarez J.D.
- Ălvarez M.Dovale
- Ć mĂda R.
- Ć upĂk J.
- ƻarnecki A.F.
- ƻywucka N.
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
International audienceOn 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of âŒ1.7s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg(2) at a luminosity distance of 40â8+8â Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mââ. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at âŒ40Mpc) less than 11 hours after the merger by the One-Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over âŒ10 days. Following early non-detections, X-ray and radio emission were discovered at the transientâs position âŒ9 and âŒ16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC 4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta