107 research outputs found

    Proportion of transcriptionally active DNA virus integrants: a meta-analysis

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    Longitudinal and Transverse Wakefields Simulations and Studies in Dielectric-Coated Circular Waveguides

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    In recent years, there has been a growing interest and rapid experimental progress on the use of e.m. fields produced by electron beams passing through dielectric-lined structures and on the effects they might have on the drive and witness bunches. Short ultra-relativistic electron bunches can excite very intense wakefields, which provide an efficient acceleration through the dielectric wakefield accelerators (DWA) scheme with higher gradient than that in the conventional RF LINAC. These beams can also generate high power narrow band THz coherent Cherenkov radiation. These high gradient fields may create strong instabilities on the beam itself causing issues in plasma acceleration experiments (PWFA), plasma lensing experiments and in recent beam diagnostic applications. In this work we report the results of the simulations and studies of the wakefields generated by electron beams at different lengths and charges passing on and off axis in dielectric-coated circular waveguides. We also propose a semi-analytical method to calculate these high gradient fields without resorting to time consuming simulations

    Thermal simulations for optical transition radiation screen for Eli-NP compton gamma source

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    The ELI-NP GBS (Extreme Light Infrastructure-Nuclear Physics Gamma Beam Source) is a high brightness elec-tron LINAC that is being built in Romania. The goal for this facility is to provide high luminosity gamma beam through Compton Backscattering. A train of 32 bunches at 100Hz with a nominal charge of 250pC is accelerated up to 740 MeV. Two interaction points with an IR Laser beam produces the gamma beam at different energies. In order to measure the electron beam spot size and the beam proper-ties along the train, the OTR screens must sustain the ther-mal and mechanical stress due to the energy deposited by the bunches. This paper is an ANSYS study of the issues due to the high quantity of energy transferred to the OTR screen. They will be shown different analysis, steady-state and thermal transient analysis, where the input loads will be the internal heat generation equivalent to the average power, deposited by the ELI-GBS beam in 512 ns, that is the train duration. Each analyses will be followed by the structural analysis to investigate the performance of the OTR materi

    Optical issues for the diagnostic stations for the ELI-NP compton gamma source

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    A high brightness electron Linac is being built in the Compton Gamma Source at the ELI Nuclear Physics facility in Romania. To achieve the design luminosity, a train of 32 bunches, 16 ns spaced, with a nominal charge of 250 pC will collide with the laser beam in the interaction point. Electron beam spot size is measured with optical transition radiation (OTR) profile monitors. In order to measure the beam properties, the optical radiation detecting system must have the necessary accuracy and resolution. This paper deals with the studies of different optic configurations to achieve the magnification, resolution and accuracy in order to measure very small beam (below 30 μm) or to study the angular distribution of the OTR and therefore the energy of the beam. Several configurations of the optical detection line will be studied both with simulation tools (e.g. Zemax) and experimentally. The paper will deal also with the sensibility of optic system (in terms of depth of field, magnification and resolution) to systematic error

    Heterogeneity of Antiphospholipid Syndrome (APS) as Characterized by Brain Perfusion Techniques. Towards New Ways of Syndrome Characterization

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    Antiphospholipid Syndrome (APS) syndrome is an autoimmune condition that affects the way that blood cells in humans bind together. Though the cause of APS is unclear, researchers believe that many factors have an impact on developing this pathological condition. Phospholipids (PLs) play numerous central roles in biological systems, and processes of biological systems regulation act through the liberation of a vast amount of different signalling molecules, which are also involved in the modulation of cell proliferation, inflammation, oxidative stress, neurotransmission and many other processes.A global landmark, holistic, is required to evaluate different phenotypes in APS. All thecriteria validated for the APS diagnosislead to an extremely heterogeneous landmark of the pathology and related to several manifestations in different systems. Heterogeneity also characterizes the SPECT acquisition of the patients and it is connected to several neurological and underestimates symptoms of the pathology. We present some examples to highlight the connection between heterogeneity in SPECT and APS markers of pathology indicating the needs to approach to the Syndrome in a holistic way. At the end of the paper we suggested the multidisciplinary approach that we are tuning for our analysis, approach based on Imaging, Metabolomic and Clinical evaluation, including mental health test for a neuropsychiatric characterization of the pathology

    Misure di temperatura di rumore con diversi materiali, sulla copertura del Gregoriano di SRT

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    Lo scopo di questo lavoro è quello di valutare l’incremento della temperatura di rumore nei ricevitori banda K (18 - 26 GHz) e banda C (5.5 – 7.7 GHz), posizionati, rispettivamente, nel fuoco gregoriano e nella Beam waveguide del Sardinia Radio Telescope (SRT), in seguito all’inserimento di una nuova protezione come copertura della Vertex room. La necessità di tale studio è dovuta alle criticità presentate dall’attuale materiale usato come protezione della stanza del fuoco gregoriano del radio telescopio. Il materiale di base attualmente in uso è lo Styrodur 3035CS, un polistirene espanso estruso che ha un bassissima attenuazione, come dimostrato dal suo notevole utilizzo nelle finestre dei diversi ricevitori sviluppati in questi anni all’INAF, ma con l’inconveniente di peggiorare le sue prestazioni col tempo a causa dei danni procurati dagli agenti atmosferici (quali raggi UV, pioggia, ghiaccio). Al fine di ridurre l’usura dello Styrodur, abbiamo testato l’utilizzo di diversi elementi protettivi superficiali come vernici, prodotti idrorepellenti e teli di Goretex e polietilene, stimando l’effetto di queste protezioni sulla temperatura di rumore del sistema. Per tale verifica è stata misurata la variazione della temperatura di sistema Tsys del radiotelescopio al variare del tipo di protezione utilizzato
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