Factors Contributing To Student-Athlete Retention

The purpose of this study was to determine the effect of scholarship support, gender and sport-type (individual or team) on student-athlete retention. Student-athlete retention was defined by utilizing the Academic Progress Rate (APR) instituted by the National Collegiate Athletic Association in February, 2005. A single mid-major Division I Conference provided data (eight institutions) on student-athletes participating from 2001-2005, resulting in 12,980 total observations. Data were analyzed utilizing analysis of variance (ANOVA), discriminant function analysis, and binary logistic regression to determine the extent to which scholarship support, gender and sport type influenced retention. Results indicated scholarship support alone was not significantly related to retention; however, gender and sport type were significant predictors of retention with female and individual sport athletes retained at a higher rate than their male and team sport counterparts. Additionally, the combination of scholarship support, gender and sport type emerged as a significant predictor of retention. These findings indicated certain populations of student-athletes leave institutions at a higher rate than others, and may suggest a need to target retention efforts at particular sub-sets of student-athletes

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020

Fixed-dose-rate gemcitabine. A viable first-line treatment option for advanced pancreatic and biliary tract cancer

Background. We have already reported on fixed-dose-rate gemcitabine (FDR-Gem) in advanced, inoperable pancreatic ductal adenocarcinoma (PDAC) and biliary tract cancer (BTC) in the context of a formal phase II study; building on that experience, we have now expanded the study to reach a cumulative accrual of 106 patients. Methods. One hundred six patients (PDAC/BTC, 75/31) were treated with weekly FDR-Gem (1,000 mg/m2infused at 10 mg/m2per minute). Patient characteristics included: male-to-female ratio, 0.83; median age, 63 years (range, 28-82); metastatic disease in 66% of patients; and an Eastern Cooperative Oncology Group performance status (ECOG PS) score of 0-1 in 81% of patients. Results. The median and total number of treatment weeks delivered were 8 (range, 2-22) and 1,154, respectively. Thirteen percent of patients achieved an objective response, 42% experienced a positive clinical benefit response, and 54% achieved a >50% reduction in serum cancer antigen (CA)19.9 levels. The median progression-free survival (PFS) and overall survival (OS) times for the entire population were 4.4 months (95% confidence interval [CI], 3.5-5.1 months) and 7.7 months (95% CI, 6.3-8.8 months), respectively, with 20% of patients alive at 1 year. On multivariate analysis, a CA19.9 reduction >50% and baseline ECOG PS score of 0 were the only independent predictors of PFS and OS, respectively. Treatment was well tolerated, with grade 3-4 neutropenia in 47 of 1,154 treatment weeks (4.1%), and grade 3 anemia and thrombocytopenia in 8 of 1,154 (0.7%) and 16 of 1,154 (1.4%) treatment weeks, respectively. Conclusions. Currently available evidence, including this updated analysis, supports the use of FDR-Gem as a first-line option in advanced PDAC, and possibly in BTC, patients and prompts the continued evaluation of this approach in combination regimens

On the Track of the Books Scribes, Libraries and Textual Transmission

Aims and Scope This book offers the hint for a new reflection on ancient textual transmission and editorial practices in Antiquity.In the first section, it retraces the first steps of the process of ancient writing and editing. The reader will discover how the book is both a material object and a metaphorical personification, material or immaterial. The second section will focus on corpora of Greek texts, their formation, and their paratextual apparatus. Readers will explore various issues dealing with the mechanisms that are at the basis of the assembling of ancient Greek texts, but great attention will also be given to the role of ancient scholarly work. The third section shows how texts have two levels of authorship: the author of the text, and the scribe who copies the text. The scribe is not a medium, but plays a crucial role in changing the text. This section will focus on the protagonists of some interesting cases of textual transmission, but also on the books they manufactured or kept in the libraries, and on the words they engraved on stones. Therefore, the fresh voices of the contributors of this book, offer new perspectives on established research fields dealing with textual criticism