The Challenge of Evaluating the Intensity of Short Actions in Soccer: a New Methodological Approach Using Percentage Acceleration

Purpose: There are several approaches to quantifying physical load in team sports using positional data. Distances in different speed zones are most commonly used. Recent studies have used acceleration data in addition in order to take short intense actions into account. However, the fact that acceleration decreases with increasing initial running speed is ignored and therefore introduces a bias. The aim of our study was to develop a new methodological approach that removes this bias. For this purpose, percentage acceleration was calculated as the ratio of the maximal acceleration of the action (amax,action) and the maximal voluntary acceleration (amax) that can be achieved for a particular initial running speed (percentage acceleration [%] = amax,action / amax * 100). Methods: To define amax, seventy-two highly trained junior male soccer players (17.1 ± 0.6 years) completed maximal sprints from standing and three different constant initial running speeds (vinit; trotting: ~6.0 km·h-1; jogging: ~10.8 km·h-1; running: ~15.0 km·h-1). Results: The amax was 6.01 ± 0.55 from a standing start, 4.33 ± 0.40 from trotting, 3.20 ± 0.49 from jogging and 2.29 ± 0.34 m·s-2 from running. The amax correlated significantly with vinit (r = -0.98) and the linear regression equation of highly-trained junior soccer players was: amax = -0.23 * vinit + 5.99. Conclusion: Using linear regression analysis, we propose to classify high-intensity actions as accelerations >75% of the amax, corresponding to acceleration values for our population of >4.51 initiated from standing, >3.25 from trotting, >2.40 from jogging, and >1.72 m·s-2 from running. The use of percentage acceleration avoids the bias of underestimating actions with high and overestimating actions with low initial running speed. Furthermore, percentage acceleration allows determining individual intensity thresholds that are specific for one population or one single player

Assessment of Orbital Compartment Pressure: A Comprehensive Review.

The orbit is a closed compartment defined by the orbital bones and the orbital septum. Some diseases of the orbit and the optic nerve are associated with an increased orbital compartment pressure (OCP), e.g., retrobulbar hemorrhage or thyroid eye disease. Our aim was to review the literature on the different approaches to assess OCP. Historically, an assessment of the tissue resistance provoked by the retropulsion of the eye bulb was the method of choice for estimating OCP, either by digital palpation or with specifically designed devices. We found a total of 20 articles reporting direct OCP measurement in animals, cadavers and humans. In nine studies, OCP was directly measured in humans, of which five used a minimally invasive approach. Two groups used experimental/custom devices, whilst the others applied commercially available devices commonly used for monitoring the compartment syndromes of the limbs. None of the nine articles on direct OCP measurements in humans reported complications. Today, OCP is mainly estimated using clinical findings considered surrogates, e.g., elevated intraocular pressure or proptosis. These diagnostic markers appear to reliably indicate elevated OCP. However, particularly minimally invasive approaches show promises for direct OCP measurements. In the future, more sophisticated, specifically designed equipment might allow for even better and safer measurements and hence facilitate the diagnosis and monitoring of orbital diseases

The challenge of evaluating the intensity of short actions in soccer: a new methodological approach using percentage acceleration

There are several approaches to quantifying physical load in team sports using positional data. Distances in different speed zones are most commonly used. Recent studies have used acceleration data in addition in order to take short intense actions into account. However, the fact that acceleration decreases with increasing initial running speed is ignored and therefore introduces a bias. The aim of our study was to develop a new methodological approach that removes this bias. For this purpose, percentage acceleration was calculated as the ratio of the maximal acceleration of the action (amax,action) and the maximal voluntary acceleration (amax) that can be achieved for a particular initial running speed (percentage acceleration [%] = amax,action / amax * 100).MethodsTo define amax, seventy-two highly trained junior male soccer players (17.1 ± 0.6 years) completed maximal sprints from standing and three different constant initial running speeds (vinit; trotting: ~6.0 km·h⁻¹; jogging: ~10.8 km·h⁻¹; running: ~15.0 km·h⁻¹).ResultsThe amax was 6.01 ± 0.55 from a standing start, 4.33 ± 0.40 from trotting, 3.20 ± 0.49 from jogging and 2.29 ± 0.34 m·s⁻² from running. The amax correlated significantly with vinit (r = –0.98) and the linear regression equation of highly-trained junior soccer players was: amax = –0.23 * vinit + 5.99.ConclusionUsing linear regression analysis, we propose to classify high-intensity actions as accelerations >75% of the amax, corresponding to acceleration values for our population of >4.51 initiated from standing, >3.25 from trotting, >2.40 from jogging, and >1.72 m·s⁻² from running. The use of percentage acceleration avoids the bias of underestimating actions with high and overestimating actions with low initial running speed. Furthermore, percentage acceleration allows determining individual intensity thresholds that are specific for one population or one single player

PI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis

New therapeutic approaches to counter the increasing prevalence of obesity and type 2 diabetes mellitus are in high demand. Deregulation of the phosphoinositide-3-kinase (PI3K)/v-akt murine thymoma viral oncogene homologue (AKT), mitogen-activated protein kinase (MAPK) and AMP-activated protein kinase (AMPK) pathways, which are essential for glucose homeostasis, often results in obesity and diabetes. Thus, these pathways should be attractive therapeutic targets. However, with the exception of metformin, which is considered to function mainly by activating AMPK, no treatment for the metabolic syndrome based on targeting protein kinases has yet been developed. By contrast, therapies based on the inhibition of the PI3K/AKT and MAPK pathways are already successful in the treatment of diverse cancer types and inflammatory diseases. This contradiction prompted us to review the signal transduction mechanisms of PI3K/AKT, MAPK and AMPK and their roles in glucose homeostasis, and we also discuss current clinical implication

Unusual Masquerading Infraorbital Mass-A Case Report of Human Ocular Dirofilariosis Found in A Ukrainian Patient in Switzerland.

A 78-year-old Ukrainian woman who had immigrated to Switzerland presented with a rapid growing subcutaneous infraorbital mass. Surgical excision of the mass revealed a well-circumscribed, encapsulated tumor, adherent to the skin. The excision showed a soft tissue inflammation with parts of Dirofilaria spp. The number of cases of human dirofilariosis reported in the last 50 years has gradually increased. Dirofilaria repens is now endemic in many countries and is currently considered to be one of the fast spreading zoonoses in Central, Eastern and Northern Europe. The first empirical evidence of Swiss spreading of D. repens infections was in a dog from southern Switzerland in 1998. Ours is the first case of human orbital dirofilariosis found in a Ukranian patient reported in Switzerland. Our purpose is to inform the ophthalmologist to consider orbital dirofilariosis in the differential diagnosis of inflammatory masses of the orbit and to warn about the spread of this infection in Switzerland

Evaluation of Bicanalicular Nasolacrimal Duct Intubation as an Adjunct in Surgical Ectropion Correction.

Background and Objectives: We aimed to analyze and compare the outcomes of conventional ectropion surgery procedures with and without concurrent bicanalicular nasolacrimal duct intubation to identify if the combination of procedures could serve as a novel surgical approach to treat lower eyelid ectropion. Materials and Methods: A retrospective review of all patients who underwent surgical correction for lower eyelid ectropion at the Cantonal Hospital of Aarau between January 2019 and December 2020 was performed. Patient medical records were examined for etiology, surgical correction technique and intra- and postoperative complications. The postoperative punctal position, the pre- and postoperative epiphora and reoperation rate were also documented. Two study groups consisting of cases with isolated and combined procedures were compared, with respect to postoperative punctual and lower lid position. Results: A total of 53 lower eyelids (35 patients) were included in this study. Six months postoperatively, the correct punctum position (p = 0.1188) and improvement of epiphora (p = 0.7739) did not significantly differ between the two groups. More complications were seen in the nasolacrimal duct intubation group (p = 0.0041), which consisted of cheese wiring and one tube dislocation. Conclusion: In our study, bicanalicular nasolacrimal intubation during ectropion surgery does not seem to improve the outcome of ectropion surgery and is, therefore, not recommended on a routine basis

Explosivkraftniveau der unteren Extremitäten bei Schweizer Nachwuchsathleten

Die Bedeutung der Explosivkraft als Leistungsvoraussetzung für schnelle, azyklische und zyklische Bewegungen in vielen Sportarten nimmt zu. Die Leistungsdiagnostik als Teil der Leistungs- und Trainingssteuerung benötigt als Grundlage für die Trainingsempfehlungen Kenngrössen oder Normwerte. Einzelne Diagnostik-Verfahren werden zunehmend bereits im Junioren- oder Nachwuchsbereich eingesetzt. Es bestand daher die Absicht, das Explosivkraftniveau der unteren Extremitäten von Schweizer Nachwuchsathleten aus verschiedenen Sportarten und verschiedenen Altersklassen zu ermitteln. 1518 Athleten (870 männlich und 648 weiblich) aus 21 verschiedenen Sportarten (18 männlich und 17 weiblich) in den Altersklassen bis 12, 14, 16, 18 und 20 Jahre absolvierten in einer Trainingslagerwoche beim «Talenttreff in Tenero (3T)» einen Sprungkrafttest (bestehend aus Countermovementjump [CMJ], Squatjump und einbeinigen Sprüngen links und rechts) auf Kraftmessplatten. Dabei wurde die relative maximale mechanische Leistung (Pmax) und die Sprunghöhe gemessen, sowie das bilaterale Defizit errechnet. Aufgeteilt nach Sportart, Geschlecht und Altersklasse wurden für diese Parameter Mittelwerte und Standardabweichungen umfangreich dokumentiert. Die Grösse der Explosivkraftwerte im Nachwuchsbereich schwankte erwartungsgemäss nach dem jeweiligen Anforderungsprofil der Sportart und nach der Altersklasse beim CMJ-Mittelwert Pmax zwischen 38.9 W/kg (Badminton U12) bis 66.6 W/kg (LA-Sprint U18) bei den Jungen und zwischen 35.3 W/kg (Squash U14) bis 55.2 W/kg (LA-Sprint U16) bei den Mädchen. Bei den 12-jährigen ist das Explosivkraftniveau der unteren Extremiäten zwischen Jungen und Mädchen praktisch identisch. Danach entwickeln sich Jungen immer besser bis zu einer Differenz von ca. 17% ab dem 18. Lebensjahr. Als Referenz für die Normierung der Explosivkraftmessungen der unteren Extremitäten ist diese Dokumentation aus 21 sportartspezifischen Kadermittelwerten im Altersbereich zwischen 12 und 20 Jahren sicher geeignet. Diese bilden dann eine Basis für eine sportgerechte individuelle Beratung