132 research outputs found

    Characterizing the Global Crowd Workforce: A Cross-Country Comparison of Crowdworker Demographics

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    Micro-task crowdsourcing is an international phenomenon that has emerged during the past decade. This paper sets out to explore the characteristics of the international crowd workforce and provides a cross-national comparison of the crowd workforce in ten countries. We provide an analysis and comparison of demographic characteristics and shed light on the significance of micro-task income for workers in different countries. This study is the first large-scale country-level analysis of the characteristics of workers on the platform Figure Eight (formerly CrowdFlower), one of the two platforms dominating the micro-task market. We find large differences between the characteristics of the crowd workforces of different countries, both regarding demography and regarding the importance of micro-task income for workers. Furthermore, we find that the composition of the workforce in the ten countries was largely stable across samples taken at different points in time

    Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis

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    Sds22 defines protein phosphatase 1 location and function at kinetochores and subsequent activity of aurora B in mitosis

    Enhancing Acceptance and Trust in Automated Driving trough Virtual Experience on a Driving Simulator

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    As vehicle driving evolves from human-controlled to autonomous, human–machine interaction ensures intuitive usage as well as the feedback from vehicle occupants to the machine for optimising controls. The feedback also improves understanding of the user satisfaction with the system behaviour, which is crucial for determining user trust and, hence, the acceptance of the new functionalities that aim to improve mobility solutions and increase road safety. Trust and acceptance are potentially the crucial parameters for determining the success of autonomous driving deployment in wider society. Hence, there is a need to define appropriate and measurable parameters to be able to quantify trust and acceptance in a physically safe environment using dependable methods. This study seeks to support technical developments and data gathering with psychology to determine the degree to which humans trust automated driving functionalities. The primary aim is to define if the usage of an advanced driving simulator can improve consumer trust and acceptance of driving automation through tailor-made studies. We also seek to measure significant differences in responses from different demographic groups. The study employs tailor-made driving scenarios to gather feedback on trust, usability and user workload of 55 participants monitoring the vehicle behaviour and environment during the automated drive. Participants’ subjective ratings are gathered before and after the simulator session. Results show a significant increase in trust ensuing the exposure to the driving automation functionalities. We quantify this increase resulting from the usage of the driving simulator. Those less experienced with driving automation show a higher increase in trust and, therefore, profit more from the exercise. This appears to be linked to the demanded participant workload, as we establish a link between workload and trust. The findings provide a noteworthy contribution to quantifying the method of evaluating and ensuring user acceptance of driving automation. It is only through the increase of trust and consequent improvement of user acceptance that the introduction of the driving automation into wider society will be a guaranteed success

    Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

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    During mitosis in most eukaryotic cells, chromosomes align and form a metaphase plate halfway between the spindle poles, about which they exhibit oscillatory movement. These movements are accompanied by changes in the distance between sister kinetochores, commonly referred to as breathing. We developed a live cell imaging assay combined with computational image analysis to quantify the properties and dynamics of sister kinetochores in three dimensions. We show that baseline oscillation and breathing speeds in late prometaphase and metaphase are set by microtubule depolymerases, whereas oscillation and breathing periods depend on the stiffness of the mechanical linkage between sisters. Metaphase plates become thinner as cells progress toward anaphase as a result of reduced oscillation speed at a relatively constant oscillation period. The progressive slowdown of oscillation speed and its coupling to plate thickness depend nonlinearly on the stiffness of the mechanical linkage between sisters. We propose that metaphase plate formation and thinning require tight control of the state of the mechanical linkage between sisters mediated by centromeric chromatin and cohesion

    Measuring motivations of crowdworkers: The multidimensional crowdworker motivation scale

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    Crowd employment is a new form of short-term and flexible employment which has emerged during the past decade. In order to understand this new form of employment, it is crucial to illuminate the underlying motivations of the workforce involved in it. This paper introduces the Multidimensional Crowdworker Motivation Scale (MCMS), a scale for measuring the motivation of crowdworkers on micro-task platforms. The MCMS is theoretically grounded in self-determination theory and tailored specifically to the context of paid crowdsourced micro-labor. The scale measures the motivation of crowdworkers along six motivational dimensions, ranging from amotivation to intrinsic motivation. We validated the MCMS on data collected in ten countries and three income groups. Factor analyses demonstrated that the MCMS's six dimensions showed good model fit, validity, and reliability. Furthermore, our measurement invariance tests showed that motivations measured with the MCMS are comparable across countries and income groups, and we present a first cross-country comparison of crowdworker motivations. This work constitutes an important first step towards understanding the motivations of the international crowd workforce.Comment: 33 pages; added section; additional validation; corrected typo

    Left ventricular ejection fraction and cardiac biomarkers for dynamic prediction of cardiotoxicity in early breast cancer

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    BACKGROUND/PURPOSE: This study aims to quantify the utility of monitoring LVEF, hs-cTnT, and NT-proBNP for dynamic cardiotoxicity risk assessment in women with HER2+ early breast cancer undergoing neoadjuvant/adjuvant trastuzumab-based therapy. MATERIALS AND METHODS: We used joint models of longitudinal and time-to-event data to analyze 1,136 echocardiography reports and 326 hs-cTnT and NT-proBNP measurements from 185 women. Cardiotoxicity was defined as a 10% decline in LVEF below 50% and/or clinically overt heart failure. RESULTS: Median pre-treatment LVEF was 64%, and 19 patients (10%) experienced cardiotoxicity (asymptomatic n = 12, during treatment n = 19). The pre-treatment LVEF strongly predicted for cardiotoxicity (subdistribution hazard ratio per 5% increase in pre-treatment LVEF = 0.68, 95%CI: 0.48–0.95, p = 0.026). In contrast, pre-treatment hs-cTnT and NT-proBNP were not consistently associated with cardiotoxicity. During treatment, the longitudinal LVEF trajectory dynamically identified women at high risk of developing cardiotoxicity (hazard ratio per 5% LVEF increase at any time of follow-up = 0.36, 95% CI: 0.2–0.65, p = 0.005). Thirty-four patients (18%) developed an LVEF decline ≥ 5% from pre-treatment to first follow-up (“early LVEF decline”). One-year cardiotoxicity risk was 6.8% in those without early LVEF decline and pre-treatment LVEF ≥ 60% (n = 117), 15.9% in those with early LVEF decline or pre-treatment LVEF 5% during trastuzumab-based therapy. The longitudinal LVEF trajectory but not hs-cTnT or NT-proBNP allows for a dynamic assessment of cardiotoxicity risk in this setting

    The Hatfield-System versus the Weekly Undulating Periodised Resistance Training in trained males: Effects of a third mesocyle

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    We recently demonstrated that recreationally strength trained men, randomly assigned to either a Hatfield-System (HAT) group or a weekly undulating periodisation (WUP) group showed significant increases in strength and power during only 2 mesocycles (6 weeks) without differences between groups. The questions arise, whether an additional mesocycle would further enhance strength and power equally or differently between groups. The same 26 strength trained men, assigned to the HAT (n = 13; age = 26.8 ± 7.2 years) or to WUP (n = 13; age = 29.2 ± 9.0 years) performed an additional mesocycle (3 weeks). Anthropometric measures and strength testing were performed again after finishing the third mesocycle and were then compared with the results recorded after the second mesocycle. Both the HAT and WUP groups made significant (p ≤ 0.05) increases in strength and power – to approximately the same extent, again, without significant differences between groups. Thus, HAT and WUP are similarly effective over a nine-week training period, and the decision to use HAT or WUP depends on the preferences of the individual athlete
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