Nubian Complex reduction strategies in Dhofar, southern Oman

AbstractBetween 2010 and 2012, the Dhofar Archaeological Project has located and mapped 260 Nubian Complex occurrences across Dhofar, southern Oman. Many of these lithic assemblages are technologically homologous to the Late Nubian Industry found in Africa, while others may represent a local industry derived from classic Nubian Levallois technology. The purpose of this paper is to describe the various reduction strategies encountered at a sample of Nubian Complex sites from Dhofar, to explore inter-assemblage variability, and, ultimately, to begin to articulate technological units within the “Dhofar Nubian Tradition.” To achieve this aim, we have developed an analytical scheme with which to describe variability among Nubian Levallois reduction strategies. From our analysis, we are able to discern at least two distinct industries within a regional lithic tradition. Demographic implications of the enduring Dhofar Nubian Tradition are considered in light of new evidence found throughout the Arabian Peninsula

Le gisement pléistocène moyen de Galeria Pesada (Estrémadure, Portugal) : premiers résultats

Les fouilles de la grotte de Galeria Pesada (complexe karstique d’Almonda, Torres Novas) livrent de riches assemblages lithiques et osseux datés du Pléistocène moyen final (fouilles 1997-1999). Les ensembles lithiques sont caractérisés par une combinaison d’outils classiques de l’Acheuléen, d’une abondante série d’outils bifaciaux (foliacés, petits bifaces asymétriques, Keilmesser, etc.) et de nombreux racloirs, souvent en quartz. Cette industrie n’a pas d’équivalent jusqu’à présent dans la Péninsule ibérique. Elle est associée à une faune dominée par les Cervidés et les Equidés dont les ossements présentent un fort pourcentage de marques de boucherie, démontrant une exploitation intensive (consommation) des carcasses par les anciens hominidés.Excavations at the late Middle Pleistocene cave site of Galeria Pesada in Portuguese Estremadura have uncovered a series of lithic assemblages associated with abundant faunal remains (Excavations 1997-1999). The lithic assemblages are all similar and consist of a combination of a few classic Acheulean tools, a rich series of bifacial tools (foliates, small asymmetric bifaces, Keilmesser, etc.), and a large number of scrapers, often on quartz. These assemblages, unknown to date in the rest of Iberia, are associated with Cervids and Equids, cut marks on bones indicate extensive and intensive carcass modification and consumption by hominids

Multimodal therapy in an inpatient setting

Inpatient Multimodal Therapy (imt) is a residential treatment program, lasting a maximum of 36 weeks, for patients with severe neurotic symptoms. A group of 44 chronic obsessive-compulsive patients and a group of 40 chronic phobic patients were treated in order to assess the outcome and the process of treatment and to identify prognostic factors associated with the effect. At follow-up-on average, eight months after discharge-it was found that 60% had improved, 32% had remained the same, and 8% had deteriorated, indicating that, in general, the treatment was beneficial. That these effects were long-lasting is supported by the fact that, at follow-up, 78% of all patients were no longer receiving treatment, 18% were receiving outpatient or day treatment, and 4% were receiving inpatient treatment. Phobic patients appear to have gained more from the multimodal approach than did obsessive-compulsive patients, as indicated by the fact that the severity of symptoms decreased as they improved in rational thinking, assertiveness, and arousal. By contrast, obsessive-compulsive patients relapsed more than phobic patients did. This was attributed to the fact that the former gained less from the rational-emotive training, denied problems with assertiveness, and did not practice the acquired relaxation skills. It further appeared that a favorable outcome could be induced in patients who (1) expressed relatively mild symptoms in this otherwise severe group, (2) reported relatively few additional complaints, (3) could clearly indicate interpersonal problems, and (4) did not use psychotropic drugs. These prognostic factors are so widespread that not much weight can be ascribed to them. Yet they are useful for indication of imt until better predictors are found

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types