53 research outputs found
Ăcrire-rĂȘver le rapport Ă la pratique professionnelle dâun coordonnateur dâULIS collĂšge : la rĂ©pĂ©tition dâune rĂ©alitĂ© inrĂȘvĂ©e
Pour ma recherche doctorale, jâai explorĂ© le rapport de certains coordonnateurs dâULIS collĂšge (unitĂ© localisĂ©e pour lâinclusion scolaire) Ă leurs propres pratiques professionnelles en France. Dans le cadre du projet nationale pour une Ă©cole inclusive, les coordonnateurs dâULIS sont des enseignants spĂ©cialisĂ©s qui proposent un enseignement adaptĂ© auprĂšs des Ă©lĂšves reconnus en situation de handicap et mettent en Ćuvre le PPS (projet personnalisĂ© de scolarisation), conçu pour chacun dâentre eux, en collaboration Ă©troite avec les autres enseignants et acteurs du mĂ©dico-social. Ă partir dâune approche clinique d'orientation psychanalytique en sciences de lâĂ©ducation et de la formation, jâai souhaitĂ© explorer comment les enseignants spĂ©cialisĂ©s occupant cette fonction complexe vivaient leur mĂ©tier sur le plan psychique. Dans cette perspective, jâai menĂ© des entretiens cliniques de recherche avec quatre professionnels. Ici, jâexpose le dispositif dâanalyse des entretiens mis en place dans lâaprĂšs-coup et la place particuliĂšre de lâĂ©criture comme une modalitĂ© dâĂ©laboration psychique. InspirĂ© des travaux de T. Ogden (1994, 2005), le terme « Ă©crire-rĂȘver » dĂ©signe la rĂȘverie sous-tendant le processus dâĂ©criture dans ce dispositif, qui permet la reprĂ©sentabilitĂ© du lien interviewer-interviewĂ© en rapport avec la pratique professionnelle. Pour illustrer ce propos, je prĂ©sente lâanalyse dâun seul entretien avec un coordonnateur, en restituant le chemin qui mâa amenĂ© Ă l'hypothĂšse de lâactualisation dâune rĂ©alitĂ© « inrĂȘvĂ©e » (Ogden, 2005) dans lâentretien en rapport avec son lien aux autres enseignants du collĂšge. Para minha pesquisa de doutorado, explorei a relação de certos coordenadores das ULIS ColĂ©gio (Unidades Localizadas para a InclusĂŁo Escolar - em colĂ©gios) com suas prĂłprias prĂĄticas profissionais na França. No Ăąmbito do projeto nacional para uma escola inclusiva, os coordenadores das ULIS sĂŁo professores especializados que oferecem um ensino adaptado a alunos reconhecidos como portadores de necessidades especiais. Eles tambĂ©m implementam o PPS (Projeto Personalizado de Escolarização), concebido para cada aluno, em estreita colaboração com os outros professores e atores mĂ©dico-sociais. A partir de uma abordagem clĂnica de orientação psicanalĂtica em ciĂȘncias da educação e da formação, quis explorar como os professores especializados que ocupam essa função complexa vivenciam seu quotidiano no plano psĂquico. Nessa perspectiva, realizei entrevistas de pesquisa clĂnica com quatro profissionais. Aqui, exponho o dispositivo de anĂĄlise das entrevistas implementado no a posteriori e o lugar particular da escrita como modalidade de elaboração psĂquica. Inspirado no trabalho de T. Ogden (1994, 2005), o termo "escrever-como-sonhar" designa o devaneio [rĂȘverie] subjacente ao processo de escrita nesse dispositivo, o que permite a representatividade do vĂnculo entrevistador-entrevistado em relação Ă prĂĄtica profissional. Para ilustrar esse ponto, apresento a anĂĄlise de uma Ășnica entrevista com um coordenador de uma ULIS. Mostro precisamente o caminho que me levou Ă hipĂłtese da atualização de uma realidade âinsonhĂĄvelâ (Ogden, 2005) na entrevista, em relação ao vĂnculo do coordenador com os demais professores do colĂ©gio.Para mi investigaciĂłn de doctorado, explorĂ© la relaciĂłn de ciertos coordinadores universitarios de ULIS (unidad localizada para la educaciĂłn inclusiva) con sus propias prĂĄcticas profesionales en Francia. Como parte del proyecto nacional por una escuela inclusiva, los coordinadores de ULIS son docentes que ofrecen enseñanza adaptada a alumnos con discapacidad reconocida. TambiĂ©n implementan el PPS (proyecto de escolarizaciĂłn personalizada), diseñado para cada alumno, en estrecha colaboraciĂłn con otros docentes y actores mĂ©dico-sociales. Desde un enfoque clĂnico orientado psicoanalĂticamente en ciencias de la educaciĂłn, quise explorar cĂłmo los profesores especializados que ocupan esta funciĂłn experimentan su vida cotidiana en el nivel psĂquico. En esta perspectiva, realicĂ© entrevistas de investigaciĂłn clĂnica con cuatro profesionales. AquĂ expongo el dispositivo de anĂĄlisis de las entrevistas y el lugar particular de la escritura como modalidad de elaboraciĂłn psĂquica. Inspirado en el trabajo de T. Ogden (1994, 2005), el tĂ©rmino "escribir-como-soñar" designa la ensoñaciĂłn que subyace al proceso de escritura, que permite la representabilidad del vĂnculo entrevistador-entrevistado en relaciĂłn con la prĂĄctica profesional. Para ilustrar este punto, presento el anĂĄlisis de una sola entrevista con un coordinador de ULIS. Precisamente muestro el camino que me llevĂł a la hipĂłtesis de una realidad âno soñadaâ (Ogden, 2005) que puede afectar la colaboraciĂłn del entrevistado con los demĂĄs profesores de su facultad.For my PhD research, I explored the relationship of certain ULIS coordinators (localized unit for inclusive education) to their own professional practices in French secondary school. As part of the national project for an inclusive school, coordinators of ULIS are teachers who offer adapted teaching to pupils with special educational needs. They also implement the PPS (personalized schooling project), designed for each pupil, in close collaboration with other teachers and medico-social actors. From a psychoanalytically oriented clinical approach in educational sciences, I wanted to explore how specialized teachers occupying this function experience their everyday life on the psychic level. In this perspective, I conducted clinical research interviews with four professionals. Here, I expose the device of interviews analysis and the particular place of writing as a modality of psychic elaboration. Inspired by the work of T. Ogden (1994, 2005), the term "writing-as-dreaming" designates the reverie underlying the process of writing, which allows representability of the interviewer-interviewee link in relation to the professional practice. To illustrate this point, I present the analysis of a single interview with a ULIS coordinator. I precisely show the path that led me to the hypothesis of an "undreamt" reality (Ogden, 2005) that may affect the intervieweeâs collaboration with the other teachers of his college
Galactic Nuclei in the Near-IR Probing the impact of the central engines on their host galaxies
Galaxies are the building blocks of the large-scale structures of the Universe, but they are
also very complicated structures at an individual level. They are observed to have a variety
of morphologies, colors, sizes, and general properties. According to the, currently main-
stream, Î cold dark matter (ÎCDM) cosmological model, structures in the Cosmos grow
hierarchically. Within this framework, gas-rich, rotationally supported spiral/disk galaxies
merge to form the fainter, rapidly rotating ellipticals, objects which are dynamically sup-
ported by a combination of pressure due to random motions of stars and ordered rota-
tional motions of the stars from the relic disks of the progenitor galaxies. Fainter elliptical
galaxies then merge to form giant, slowly rotating, âred and deadâ ellipticals, which are
dynamically supported by the pressure of the highly randomized motions of their, mostly,
old stars. Galaxy mergers, however, do much more than randomizing the orbits of stars,
as they also introduce a variety of important implications to galaxy evolution. The âend
storyâ of mergers is, inevitably, to create supermassive black hole (SMBH) binaries and,
possibly, SMBH recoils, both of which can transform the central regions of the remnants.
Moreover, tidal torques during mergers can remove angular momentum from the gas of
the progenitor galaxies and drive it towards the center, a process which can initiate intense
central starbursts, while it is also a very effective way to âturn onâ their central engines, in
a phenomenon known as an active galactic nucleus or AGN. An AGN, in turn, can pro-
duce massive energy outflows (i.e. AGN feedback) both in the form of mechanical energy
(e.g. winds and jets), as well as, in the form of intense radiation fields, which can affect the
evolution of a galaxy, either in a negative (e.g. quenching nuclear star formation) or in a
positive way (e.g. jet-induced star formation).
In this thesis, I present the case studies of two objects, namely, NGC3718 and
NGC5128, using near-infrared (NIR), high resolution, adaptive optics (AO) assisted data
taken with the Subaru telescope and the High-Contrast Coronographic Imager for Adap-
tive Optics (HiCIAO) instrument.
NGC3718 is an exciting object. Its morphological properties point towards a classifi-
cation as a polar ring galaxy, which is, likely, the product of a rare case of a galaxy merger,
while it is also a low luminosity AGN (LLAGN). The analysis presented here, reveals strong
indications for the presence of an SMBH recoil in NGC3718, which is further supported
by results from previous studies. Evidence that an SMBH recoil is present include the
observed NIR and radio emission spatial offsets, a candidate small-scale X-shaped radio
source, an amount of âmissing lightâ in its central region (i.e. ⌠200 pc), and the relative
shift between its broad and narrow H α lines. In an effort to incorporate all these findings
into one physically consistent scheme, I extensively discuss a possible interpretation of
these results.
NGC5128 is also a very interesting object, since it is the host of the powerful radio
source Centaurus A (Cen A). Here, I present the analysis of a field located near the northern
middle lobe (NML) of the Cen A jet, at a distance of ⌠15 kpc from the center of the galaxy.
This region has long been suspected to have undergone a jet-induced star formation âŒ
10 â 15 Myr ago, which created young blue stars arranged in OB associations. Statistical
and photometric analysis of high resolution images of the region reveals the presence of
supergiants, with estimated ages consistent with the age of the jet-induced star formation.
Finally, throughout this work I underline the great potential of high resolution, ground-
based NIR observations in exploring our Cosmos, either regarding the physical processes
that occur in the central regions of nearby galaxies, or in resolving extra-galactic dense
stellar populations (e.g. OB associations) into individual stars in galaxies beyond our Local
Group (LG)
QUANTIFICATION AND EVALUATION OF DUST RESUSPENSION PM10 EMISSIONS IN TWO LARGE URBAN CENTERS IN GREECE
In the last years resuspended dust is gaining more scientific attention as it is believed to be a significant source of
particles. In many modeling studies exhaust-pipe emissions alone, are inadequate to explain the observed ambient concentrations
values. In Greece, a country with PM10 concentrations well above the ambient threshold limits, resuspension could be the missing
link between modeled and observed concentration levels. A quantification of dust resuspension emissions in the city of Thessaloniki
was attempted based on real traffic counts and various statistical parameters and the influence of resuspended dust was investigated
with the help of an emission model developed for this purpose. The results indicated that resuspension of dust emissions was several
times more the exhaust part emissions. Moreover an evaluation method implemented in two measuring stations with different
characteristics, showed a very good agreement with the ambient concentration measurements. As exhaust-pipe emissions are
expected to go down during the next years due to the introduction of better engine technologies in the circulating fleet, non-exhaust
sources are expected to raise due to the increased number of circulating vehicles
Ăcrire-rĂȘver le rapport Ă la pratique professionnelle dâun coordonnateur dâULIS collĂšge : la rĂ©pĂ©tition dâune rĂ©alitĂ© inrĂȘvĂ©e
Pour ma recherche doctorale, jâai explorĂ© le rapport de certains coordonnateurs dâULIS collĂšge (unitĂ© localisĂ©e pour lâinclusion scolaire) Ă leurs propres pratiques professionnelles en France. Dans le cadre du projet nationale pour une Ă©cole inclusive, les coordonnateurs dâULIS sont des enseignants spĂ©cialisĂ©s qui proposent un enseignement adaptĂ© auprĂšs des Ă©lĂšves reconnus en situation de handicap et mettent en Ćuvre le PPS (projet personnalisĂ© de scolarisation), conçu pour chacun dâentre eux, en collaboration Ă©troite avec les autres enseignants et acteurs du mĂ©dico-social. Ă partir dâune approche clinique d'orientation psychanalytique en sciences de lâĂ©ducation et de la formation, jâai souhaitĂ© explorer comment les enseignants spĂ©cialisĂ©s occupant cette fonction complexe vivaient leur mĂ©tier sur le plan psychique. Dans cette perspective, jâai menĂ© des entretiens cliniques de recherche avec quatre professionnels. Ici, jâexpose le dispositif dâanalyse des entretiens mis en place dans lâaprĂšs-coup et la place particuliĂšre de lâĂ©criture comme une modalitĂ© dâĂ©laboration psychique. InspirĂ© des travaux de T. Ogden (1994, 2005), le terme « Ă©crire-rĂȘver » dĂ©signe la rĂȘverie sous-tendant le processus dâĂ©criture dans ce dispositif, qui permet la reprĂ©sentabilitĂ© du lien interviewer-interviewĂ© en rapport avec la pratique professionnelle. Pour illustrer ce propos, je prĂ©sente lâanalyse dâun seul entretien avec un coordonnateur, en restituant le chemin qui mâa amenĂ© Ă l'hypothĂšse de lâactualisation dâune rĂ©alitĂ© « inrĂȘvĂ©e » (Ogden, 2005) dans lâentretien en rapport avec son lien aux autres enseignants du collĂšge.
Re-engineering E. coli for in vivo production of fluorometabolites
Fluorinated products are widely used in pharmaceutical and agrochemical applications
where a large portion of the commercial compounds being developed
contain at least one atom of fluorine. Most of the conventional fluorination reactions
require volatile chemicals and are highly exothermic requiring controlled
procedures which are rather costly, produce low yields and exhibit low selectivity
of the moiety accepting fluorine. As a result, much attention has been drawn on
enzymatic fluorination in a quest to ameliorate these issues.
The only characterized enzyme that mediates direct fluorination is the 5'-fluoro-
5'-deoxyadenosine (5'-FDA) synthase (a.k.a. fluorinase), which uptakes an S-
adenosyl-L-methionine (SAM) molecule and a fluorine atom as substrates and
yields 5'-FDA and methionine. Variants of this enzyme have been extensively
studied structurally and functionally with in vitro assays and they exhibit very
high homology, and a similarly slow activity.
In this work, a bacterial in vivo bioreactor is presented, based on a variant of
the enzyme, which is found in Streptomyces sp. MA37 (FlA1). The base host
that has been chosen for the implementation of modiflcations is Escherichia coli
BL21(DE3), which is a host of choice for the over-expression of recombinant
proteins and in some occasions utilized for the construction of novelty bioreactors.
In the case of enzymatic fluorination, a few challenges had to be addressed.
First of all, E. coli contains an ion channel protein, termed CrcB, which expels
fluoride anions out of the cell. Secondly, SAM cannot passively enter E. coli
cells rendering the intracellular molarity of SAM a bottleneck. Last but not
least, the E. coli purine nucleoside phosphorylase, DeoD, has been suggested to
degrade the fluorination product, 5'-FDA. Therefore, the modified E. coli strain,
consists of 2 deleted genes (âcrcBâdeoâ), the expression of a SAM transporter
from Rickettsia prowazekii and the over-expression of flA1. Using this strain, in
vivo production of 5'-FDA to near millimolar concentrations has been confirmed
using an array of chemical analysis methods including High Performance Liquid
Chromatography (HPLC), Fluorine Nuclear Magnetic Resonance (F-NMR) and
High Resolution Mass Spectrometry (HRMS)
A GIS based anthropogenic PM10 emission inventory for Greece
AbstractAn anthropogenic, chemically speciated PM10 emission inventory was compiled for Greece in 10km spatial resolution. The inventory comprises of all anthropogenic particulate matter sources and it was compiled using a Geographical Information System (GIS) integrated with SQL programming language. Input data from the national and international databases were used for the calculation of spatially and temporally resolved emissions for the road transport and all the subsectors of the other mobile sources and machinery sector using topâdown or bottomâup methodologies. Annual data from existing emission databases were also used and were temporally and spatially disaggregated using source relevant statistical data and high resolution maps. The sectoral emission totals are compared with other emission databases or studies conducted in the area. Total anthropogenic emissions in Greece were estimated to be 182 219t for the base year 2003. The results indicate the industrial sector as the major PM10 emission source (39.9% contribution) with the major industrial units though to be situated inside the organised industrial areas of the country. The power generation sector (21.4%) is the second largest contributor in national level mostly derived from one specific industrial region at north. International cargo shipping activities (9.6%) is also an important source category for particles. Heat production and road transport are found to play a significant role inside the urban centres of the country
Regular Matroids with Graphic Cocircuits
We introduce the notion of graphic cocircuits and show that a large class of
regular matroids with graphic cocircuits belongs to the class of signed-graphic
matroids. Moreover, we provide an algorithm which determines whether a
cographic matroid with graphic cocircuits is signed-graphic or not
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