65 research outputs found

    Politics and eminent domain: Evidence from the 1879 California Constitution

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    This paper explores the politics of eminent domain, using a specific historical episode: the enactment of the new California constitution in 1879. It presents evidence that the failure of a constitutional provision that would have codified eminent domain powers for water development resulted from a complex interchange of economic interests among farmers, miners, and urban residents. This evidence was manifested in delegate behavior on the floor of the constitutional convention in 1878, including various roll-call votes, which are subjected to an econometric analysis. The results have implications for the interpretation of legislative eminent domain decisions, and the degree to which economic development processes are shaped by the institutional environment in which they occur

    Judicial Deference and the Efficiency of the Common Law

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    Economists and legal scholars in the law-and-economics tradition have long been occupied with the question of whether, and the extent to which, the common law is efficient. There have been two main approaches taken in the scholarly literature. One approach has been to focus on judges, who are modeled having various motivations including, but not necessarily confined to, concern for efficient allocation of resources.1 However, to the extent they are concerned with efficiency, this attitude will be reflected in their opinions.2 This argument has been subject to criticism by scholars on various grounds, including questioning the assumption that judges are principally interested in promoting efficient resource use, at the expense of other arguments in their utility function such as ideology, fairness, and professional reputation and status

    Transaction Costs in Water Transfers: The issue of local control

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    As water becomes increasingly scarce relative to demand, it becomes increasingly important to maximize the value that we derive from it. For years, economists have been advocating increased reliance on water markets as a means of rationalizing water use, the objective being to facilitate the allocation of water to its highest-value uses.1 Yet in many parts of the arid West, water markets have been surprisingly slow to take hold. Despite some recent progress, perhaps nowhere is this truer than in California.2 The conditions of extreme drought recently experienced by the state make it even more incumbent to better understand why water markets have been so slow to emerge

    The Association of Cognitive Ability with Right-wing Ideological Attitudes and Prejudice: A Meta-analytic Review

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    The cognitive functioning of individuals with stronger endorsement of right-wing and prejudiced attitudes has elicited much scholarly interest. Whereas many studies investigated cognitive styles, less attention has been directed towards cognitive ability. Studies investigating the latter topic generally reveal lower cognitive ability to be associated with stronger endorsement of right-wing ideological attitudes and greater prejudice. However, this relationship has remained widely unrecognized in literature. The present meta-analyses revealed an average effect size of r =-.20 [95% confidence interval (95% CI) [-0.23, -0.17]; based on 67 studies, N=84 017] for the relationship between cognitive ability and right-wing ideological attitudes and an average effect size of r=-.19 (95% CI [-0.23, -0.16]; based on 23 studies, N=27 011) for the relationship between cognitive ability and prejudice. Effect sizes did not vary significantly across different cognitive abilities and sample characteristics. The effect strongly depended on the measure used for ideological attitudes and prejudice, with the strongest effect sizes for authoritarianism and ethnocentrism. We conclude that cognitive ability is an important factor in the genesis of ideological attitudes and prejudice and thus should become more central in theorizing and model building

    Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis

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    This is the publisher’s final pdf. The published article is copyrighted by PLoS and can be found at: http://www.plosone.org/home.action.Background: COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal permeability barrier (EPB) establishment during development, similar to what was observed in Ctip2 null (Ctip2(-/-)) mice. Considering that as an important role of Ctip2, and the fact that molecular networks which underlie cancer progression partially overlap with those responsible for tissue remodeling, we sought to determine the role of Ctip2 during cutaneous wound healing. \ud \ud Methodology/Principal Findings: Full thickness excisional wound healing experiments were performed on Ctip2(L2/L2) and Ctip2(ep-/-) animals per time point and used for harvesting samples for histology, immunohistochemistry (IHC) and immunoblotting. Results demonstrated inherent defects in proliferation and migration of Ctip2 lacking keratinocytes during re-epithelialization. Mutant mice exhibited reduced epidermal proliferation, delayed keratinocyte activation, altered cell-cell adhesion and impaired ECM development. Post wounding, Ctip2(ep-/-) mice wounds displayed lack of E-Cadherin suppression in the migratory tongue, insufficient expression of alpha smooth muscle actin (alpha SMA) in the dermis, and robust induction of K8. Importantly, dysregulated expression of several hair follicle (HF) stem cell markers such as K15, NFATc1, CD133, CD34 and Lrig1 was observed in mutant skin during wound repair. \ud \ud Conclusions/Significance: Results confirm a cell autonomous role of keratinocytic Ctip2 to modulate cell migration, proliferation and/or differentiation, and to maintain HF stem cells during cutaneous wounding. Furthermore, Ctip2 in a non-cell autonomous manner regulated granulation tissue formation and tissue contraction during wound closure
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