Changes in quality of life and coping among people with multiple sclerosis over a 2 year period

There is a need to investigate the impact of different coping strategies on quality of life (QOL) of people with multiple sclerosis (MS), in order to better inform intervention programs for this population. This study evaluated the relationship between QOL and coping over a 2 year period among people with MS. Participants were 382 people with MS (144 male, 238 females) and 291 people without a neurological or other chronic illness from the general population (101 males, 190 females). People with MS experienced lower QOL than the control group in the domains of global QOL, independence, social and spiritual QOL scales, as well as the problem solving and social/emotional support coping scales. Interestingly, people with MS experienced higher psychological QOL than the general population, and higher detachment and focusing on the positive coping. Over time, people with MS demonstrated increases in their global QOL as well as in their social/emotional support coping. Women demonstrated higher levels than men of global QOL and Social/emotional support coping. The results of these findings have implications for information and intervention programs for people with MS. <br /

A Cyber Physical Systems Perspective on the Real-time and Reliable Dissemination of Information in Intelligent Transportation Systems

Timely and reliable dissemination of traffic-related information to drivers is a key property that intelligent transportation systems (ITS) should support. Numerous impediments stemming due to (a) physical factors, such as mobility and speed of vehicles, density of vehicles, characteristics of the wireless radio channel, and power and bit rate of radio transceivers, and (b) cyber issues, such as MAC layer access point associations and address resolutions (ARP), network layer addressing, routing and handoffs, and transport layer retransmissions lead to unpredictability in the timely and reliable dissemination of information to drivers. This paper presents compelling arguments in favor of new research directions in this area that are based on a cyber-physical systems (CPS) perspective. In particular, this paper makes three contributions. First, it considers a vehicle-centric perspective to survey and study the physics-and cyber-imposed impediments to the timely and reliable dissemination of information. Second, it presents a promising CPS solution to overcome a subset of the impediments discovered. Third, it outlines lessons learned indicating the need for more focused research and realistic testbeds. The evaluations 1 www.macrothink.org/npa Network Protocols and Algorithm

Computer Imaging to Determine Seed Quality and Performance

Author Institution (McDonald and Bennett): Department of Horticulture and Crop Science, The Ohio State University; Author Institution (Ling): Department of Food, Agricultural and Biological Engineering, The Ohio State University; Author Institution (Fujimura): Department of Computer Science and Engineering, The Ohio State Universit

Proton therapy for atypical meningiomas

We report clinical outcomes of proton therapy in patients with World Health Organization grade 2 (atypical) meningiomas. Between 2005 and 2013, 22 patients with atypical meningiomas were treated to a median dose of 63 Gy (RBE) using proton therapy, as an adjuvant therapy after surgery (n = 12) or for recurrence or progression of residual tumor (n = 10). Six patients had presumed radiation-induced meningiomas, but none had received prior radiotherapy for their meningioma. The median follow-up time after radiation was 39 months (range 7–104) and all patients remain alive at last follow-up. The 5-year estimate of local control was 71.1 % (95 % CI 49.3–92.9 %). The 5-year estimate of local control was 87.5 % following a radiation dose >60 Gy (RBE), compared to 50.0 % for ≤60 Gy (RBE) (p = 0.038). The 5-year estimate of neuraxis dissemination was 5 % (95 % CI 0–14.6 %) and 6.2 % (95 % CI 0–18.2 %) for metastases outside of the central nervous system. Radiation necrosis was observed in one patient with a history of prior cranial irradiation. Fractionated proton therapy was associated with favorable tumor control rates for grade 2 meningiomas. Prospective studies are needed to define the optimal radiation dose for high-grade meningiomas

Detecting a Currency's Dominance or Dependence using Foreign Exchange Network Trees

In a system containing a large number of interacting stochastic processes, there will typically be many non-zero correlation coefficients. This makes it difficult to either visualize the system's inter-dependencies, or identify its dominant elements. Such a situation arises in Foreign Exchange (FX) which is the world's biggest market. Here we develop a network analysis of these correlations using Minimum Spanning Trees (MSTs). We show that not only do the MSTs provide a meaningful representation of the global FX dynamics, but they also enable one to determine momentarily dominant and dependent currencies. We find that information about a country's geographical ties emerges from the raw exchange-rate data. Most importantly from a trading perspective, we discuss how to infer which currencies are `in play' during a particular period of time