550 research outputs found

    ‘Employers’ perspectives on maximising undergraduate student learning from the outdoor education centre work placement

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    Recognising the growth in provision of vocational undergraduate programmes and the requirement for high quality work placement opportunities, managers from four residential outdoor education centres were interviewed to determine their perceptions on the components necessary to maximise student learning. The findings showed that the managers greatly valued the potential of a work placement; a need for clarity over the expectations for all stakeholders and that the placement remained authentic to modern centre life. Specifically it was felt that the students on placement needed to experience all aspects of work and not just the ‘glamorous’ bits

    Acoustic Augmented Reality

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    To assess the feasibility of spatialized sound as a learning tool and to enhance and build engagement with differing environments and biodiversity using contemporary technologies

    History Mysteries: Research for a Historical-fiction Mystery Set During the 1918 Spanish Flu in New England

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    Graduate LUO Remote Creative and Artisti

    Enhancing Covid-19 Decision-Making by Creating an Assurance Case for Simulation Models

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    Simulation models have been informing the COVID-19 policy-making process. These models, therefore, have significant influence on risk of societal harms. But how clearly are the underlying modelling assumptions and limitations communicated so that decision-makers can readily understand them? When making claims about risk in safety-critical systems, it is common practice to produce an assurance case, which is a structured argument supported by evidence with the aim to assess how confident we should be in our risk-based decisions. We argue that any COVID-19 simulation model that is used to guide critical policy decisions would benefit from being supported with such a case to explain how, and to what extent, the evidence from the simulation can be relied on to substantiate policy conclusions. This would enable a critical review of the implicit assumptions and inherent uncertainty in modelling, and would give the overall decision-making process greater transparency and accountability.Comment: 6 pages and 2 figure

    Augmented reality forest soundscapes

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    Since the beginning of the lockdown response to the coronavirus pandemic the soundscape of the world around us has changed dramatically. Outdoors or in, there was a notable drop in ambient background noise that is almost exclusively down to the reduction in sound caused by humans or to use its formal term, anthropophony. In our visually dominated society this provided a rare treat for the ears, specifically the opportunity to clearly hear the sounds created by other living creatures that inhabit the world (biophony) and the non-biological sounds of the outdoors (geophony)

    Detecting BS in Health Care 2.0

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    In our initial report “Detecting BS in Health Care,” we identified our top ten BS concepts and trends within the health care industry, and encouraged our readers to hone their “BS detection skills.” Many of you have let us know that we “left some BS on the table.” For example, there are more Old English terms for BS that we missed—such as babble, bafflegab, bilge, blather, blarney, bosh—and these are just from the b’s. This time around we make bolder assertions about other possible forms of BS—including some sacred cows—that might make some readers uncomfortable

    Accountable Care Organizations: Back to the Future?

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    Accountable Care Organizations (ACOs) are networks of providers that assume risk for the quality and total cost of the care they deliver. Public policymakers and private insurers hope that ACOs will achieve the elusive “triple aim” of improving quality of care, improving population health, and reducing costs. The model is still evolving, but the premise is that ACOs will accomplish these aims by coordinating care, managing chronic disease, and aligning financial incentives for hospitals and physicians. If this sounds familiar, it may be because the integrated care networks of the 1990s tried some of the same things, and mostly failed in their attempts. This Issue Brief summarizes the similarities and differences between the new ACOs and the integrated delivery networks of the 1990s, and presents the authors’ analysis of the likely success of these new organizations in affecting the costs and quality of health care

    Paddle to the sea

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    This paper explores human and other-than-human agency through the rhythms experienced during a source to sea canoe journey from Kirkstone Pass in the centre of the Lake District to the Solway Firth.  Musing on the narrative of Holling’s (1941) children’s classic ‘Paddle to the Sea’ this study reflects on the dance of agency experienced by Hollins' character 'Paddle' alongside those which emerge during our own paddle to the sea. Acknowledging privileges in terms of agency, finances and time; what experiences would the researchers have in terms of their sense of space, time and nature connection? Findings included observations around the role of task focus on the sense of time, space and nature connection, some attractive aspects of arrhythmia and the examination of some assumed hierarchical dualities

    N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1.

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    N-Arachidonoyl dopamine (NADA) is an endogenous lipid that potently activates the transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation. NADA is also an agonist of cannabinoid receptors 1 and 2. We have reported that NADA reduces the activation of cultured human endothelial cells by LPS and TNF-α. Thus far, in vivo studies using NADA have focused on its neurologic and behavioral roles. In this article, we show that NADA potently decreases in vivo systemic inflammatory responses and levels of the coagulation intermediary plasminogen activator inhibitor 1 in three mouse models of inflammation: LPS, bacterial lipopeptide, and polymicrobial intra-abdominal sepsis. We also found that the administration of NADA increases survival in endotoxemic mice. Additionally, NADA reduces blood levels of the neuropeptide calcitonin gene-related peptide but increases the neuropeptide substance P in LPS-treated mice. We demonstrate that the anti-inflammatory effects of NADA are mediated by TRPV1 expressed by nonhematopoietic cells and provide data suggesting that neuronal TRPV1 may mediate NADA's anti-inflammatory effects. These results indicate that NADA has novel TRPV1-dependent anti-inflammatory properties and suggest that the endovanilloid system might be targeted therapeutically in acute inflammation
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