Stellar alignment of the High Resolution Doppler Imager

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77037/1/AIAA-26727-328.pd

Atmospheric wind measurements with the high-resolution Doppler imager

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76745/1/AIAA-26590-119.pd

The High Resolution Doppler Imager (HRDI) on the Upper Atmosphere Research Satellite

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76425/1/AIAA-1993-123-305.pd

Generalizing Galileons

The Galileons are a set of terms within four-dimensional effective field theories, obeying symmetries that can be derived from the dynamics of a 3+1-dimensional flat brane embedded in a 5-dimensional Minkowski Bulk. These theories have some intriguing properties, including freedom from ghosts and a non-renormalization theorem that hints at possible applications in both particle physics and cosmology. In this brief review article, we will summarize our attempts over the last year to extend the Galileon idea in two important ways. We will discuss the effective field theory construction arising from co-dimension greater than one flat branes embedded in a flat background - the multiGalileons - and we will then describe symmetric covariant versions of the Galileons, more suitable for general cosmological applications. While all these Galileons can be thought of as interesting four-dimensional field theories in their own rights, the work described here may also make it easier to embed them into string theory, with its multiple extra dimensions and more general gravitational backgrounds.Comment: 16 pages; invited brief review article for a special issue of Classical and Quantum Gravity. Submitted to CQ

Galileons as Wess-Zumino Terms

We show that the galileons can be thought of as Wess-Zumino terms for the spontaneous breaking of space-time symmetries. Wess-Zumino terms are terms which are not captured by the coset construction for phenomenological Lagrangians with broken symmetries. Rather they are, in d space-time dimensions, d-form potentials for (d+1)-forms which are non-trivial co-cycles in Lie algebra cohomology of the full symmetry group relative to the unbroken symmetry group. We introduce the galileon algebras and construct the non-trivial (d+1)-form co-cycles, showing that the presence of galileons and multi-galileons in all dimensions is counted by the dimensions of particular Lie algebra cohomology groups. We also discuss the DBI and conformal galileons from this point of view, showing that they are not Wess-Zumino terms, with one exception in each case.Comment: 49 pages. v2 minor changes, version appearing in JHE

Cosmic microwave anisotropies from BPS semilocal strings

We present the first ever calculation of cosmic microwave background CMB anisotropy power spectra from semilocal cosmic strings, obtained via simulations of a classical field theory. Semilocal strings are a type of non-topological defect arising in some models of inflation motivated by fundamental physics, and are thought to relax the constraints on the symmetry breaking scale as compared to models with (topological) cosmic strings. We derive constraints on the model parameters, including the string tension parameter mu, from fits to cosmological data, and find that in this regard BPS semilocal strings resemble global textures more than topological strings. The observed microwave anisotropy at l = 10 is reproduced if Gmu = 5.3x10^{-6} (G is Newton's constant). However as with other defects the spectral shape does not match observations, and in models with inflationary perturbations plus semilocal strings the 95% confidence level upper bound is Gmu<2.0x10^{-6} when CMB data, Hubble Key Project and Big Bang Nucleosynthesis data are used (c.f. Gmu<0.9x10^{-6} for cosmic strings). We additionally carry out a Bayesian model comparison of several models with and without defects, showing models with defects are neither conclusively favoured nor disfavoured at present.Comment: 15 pages, 13 figures. Minor correction of numerical results, matches published versio

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

TMTM simulations of tides: Comparison with UARS observations

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95593/1/grl10703.pd

TMTM simulations of tides: Comparison with UARS observations

Abstract. This paper presents combined model-data interpretation of the High Resolution Doppler Imager (HRDI) and Wind Imaging Interferometer (WINDII) wind, temperature and airglow data using the tuned mechanistic tidal model (TMTM) approach, including calculation of the nighttime oxygen emission rates induced by the simulated tides. This is the first demonstration of the consistency of the tidal signatures in the HRDI/WINDII temperature, airglow and wind observations in the mesosphere and lower thermosphere (MLT). This analysis gives increased confidence in these UARS measurements and also in our TMTM methodology