89 research outputs found

    The United States COVID-19 Forecast Hub dataset

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    Academic researchers, government agencies, industry groups, and individuals have produced forecasts at an unprecedented scale during the COVID-19 pandemic. To leverage these forecasts, the United States Centers for Disease Control and Prevention (CDC) partnered with an academic research lab at the University of Massachusetts Amherst to create the US COVID-19 Forecast Hub. Launched in April 2020, the Forecast Hub is a dataset with point and probabilistic forecasts of incident cases, incident hospitalizations, incident deaths, and cumulative deaths due to COVID-19 at county, state, and national, levels in the United States. Included forecasts represent a variety of modeling approaches, data sources, and assumptions regarding the spread of COVID-19. The goal of this dataset is to establish a standardized and comparable set of short-term forecasts from modeling teams. These data can be used to develop ensemble models, communicate forecasts to the public, create visualizations, compare models, and inform policies regarding COVID-19 mitigation. These open-source data are available via download from GitHub, through an online API, and through R packages

    Recommendations for Addressing Priority Io Science in the Next Decade

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    Io is a priority destination for solar system exploration. The scope and importance of science questions at Io necessitates a broad portfolio of research and analysis, telescopic observations, and planetary missions - including a dedicated New Frontiers class Io mission

    The Science Case for Io Exploration

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    Io is a priority destination for solar system exploration, as it is the best natural laboratory to study the intertwined processes of tidal heating, extreme volcanism, and atmosphere-magnetosphere interactions. Io exploration is relevant to understanding terrestrial worlds (including the early Earth), ocean worlds, and exoplanets across the cosmos

    Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry

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    Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase

    Internal Reactions and Metastable Dissociations after Ionization of van der Waals Clusters

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    Multiply Charged Clusters

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    Cluster Ions Measured Using Mass Spectrometry

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    Resonant Formation of Cluster Anions Containing SF6 Involving a Pick-up Experiment with Argon and Nitrogen Clusters

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    Electron attachment to species formed in an experiment involving the interaction of either Ar or N2 clusters with SF6 background gas leads to the formation of cluster anions Mm(SF6)n− containing as many as 20 monomers (M = Ar or N2) and up to five SF6 molecules, including also “pure” (SF6)n−. All of these ions are formed resonantly near 0 eV electron energy. In the case of N2 clusters, another resonance near 1.8 eV is observed which is related to (intra-cluster) auto-scavenging, involving the 2Πg transient negative ion state of solvated N2. These observations, and the absence of SF5-containing clusters, make it possible to identify unambiguously the mechanism through which the observed ions form. In a first step, mixed neutral clusters Mx(SF6)y arise from pick-up reactions; subsequent electron attachment to these species results in mixed and pure cluster ions

    Molecules and clusters embedded in helium nanodroplets

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