1,548 research outputs found
Analysis and Optimization of Mixed-Criticality Applications on Partitioned Distributed Architectures
Spin-Hall Effect in A Symmetric Quantum Wells by A Random Rashba Field
Changes dopant ion concentrations in the sides of a symmetric quantum well
are known to create a random Rashba-type spin-orbit coupling. Here we
demonstrate that, as a consequence, a finite size spin-Hall effect is also
present. Our numerical algorithm estimates the result of the Kubo formula for
the spin-Hall conductivity, by using a tight-binding approximation of the
Hamiltonian in the framework of a time-dependent Green's function formalism,
well suited for very large systems.Comment: 4 pages, 4 figures in eps forma
Prenatal diagnosis of trisomy 6q25.3-qter and monosomy 10q26.12-qter by array CGH in a fetus with an apparently normal karyotype.
We present the prenatal case of a 12.5-Mb duplication involving 6q25-qter and a 12.2-Mb deletion encompassing 10q26-qter diagnosed by aCGH, while conventional karyotype showed normal results. The genotype-phenotype correlation between individual microarray and clinical findings adds to the emerging atlas of chromosomal abnormalities associated with specific prenatal ultrasound abnormalities
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MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
BACKGROUND: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. The ability to identify them in a genome-wide manner depends on the availability of accurate models and of search methods able to detect putative regulatory elements with enhanced sensitivity and specificity. RESULTS: We describe the implementation of a search method for putative transcription factor binding sites (TFBSs) based on hidden Markov models built from alignments of known sites. We built 1,079 models of TFBSs using experimentally determined sequence alignments of sites provided by the TRANSFAC and JASPAR databases and used them to scan sequences of the human, mouse, fly, worm and yeast genomes. In several cases tested the method identified correctly experimentally characterized sites, with better specificity and sensitivity than other similar computational methods. Moreover, a large-scale comparison using synthetic data showed that in the majority of cases our method performed significantly better than a nucleotide weight matrix-based method. CONCLUSION: The search engine, available at , allows the identification, visualization and selection of putative TFBSs occurring in the promoter or other regions of a gene from the human, mouse, fly, worm and yeast genomes. In addition it allows the user to upload a sequence to query and to build a model by supplying a multiple sequence alignment of binding sites for a transcription factor of interest. Due to its extensive database of models, powerful search engine and flexible interface, MAPPER represents an effective resource for the large-scale computational analysis of transcriptional regulation
Szeg\"o kernel asymptotics and Morse inequalities on CR manifolds
We consider an abstract compact orientable Cauchy-Riemann manifold endowed
with a Cauchy-Riemann complex line bundle. We assume that the manifold
satisfies condition Y(q) everywhere. In this paper we obtain a scaling
upper-bound for the Szeg\"o kernel on (0, q)-forms with values in the high
tensor powers of the line bundle. This gives after integration weak Morse
inequalities, analogues of the holomorphic Morse inequalities of Demailly. By a
refined spectral analysis we obtain also strong Morse inequalities which we
apply to the embedding of some convex-concave manifolds.Comment: 40 pages, the constants in Theorems 1.1-1.8 have been modified by a
multiplicative constant 1/2 ; v.2 is a final updat
Spin Hall Effect in a Symmetric Quantum Well by a Random Rashba Field
Dopant ion concentrations in the sides of a symmetric quantum well are known to create a random Rashba-type spin-orbit coupling. Here, we demonstrate that, as a consequence, a finite size spin Hall effect is also present. Our numerical algorithm estimates the result of the Kubo formula for the spin Hall conductivity by using a tight-binding approximation of the Hamiltonian in the framework of a time-dependent Green’s function formalism well suited for very large systems
The first coefficients of the asymptotic expansion of the Bergman kernel of the spin^c Dirac operator
We establish the existence of the asymptotic expansion of the Bergman kernel
associated to the spin-c Dirac operators acting on high tensor powers of line
bundles with non-degenerate mixed curvature (negative and positive eigenvalues)
by extending the paper " On the asymptotic expansion of Bergman kernel "
(math.DG/0404494) of Dai-Liu-Ma. We compute the second coefficient b_1 in the
asymptotic expansion using the method of our paper "Generalized Bergman kernels
on symplectic manifolds" (math.DG/0411559).Comment: 21 pages, to appear in Internat. J. Math. Precisions added in the
abstrac
What Limits the Rate Capability of Li-S Batteries during Discharge: Charge Transfer or Mass Transfer?
Li-S batteries exhibit poor rate capability under lean electrolyte conditions required for achieving high practical energy densities. In this contribution, we argue that the rate capability of commercially-viable Li-S batteries is mainly limited by mass transfer rather than charge transfer during discharge. We first present experimental evidence showing that the charge-transfer resistance of Li-S batteries and hence the cathode surface covered by Li2S are proportional to the state-of-charge (SoC) and not to the current, directly contradicting previous theories. We further demonstrate that the observed Li-S behaviors for different discharge rates are qualitatively captured by a zero-dimensional Li-S model with transport-limited reaction currents. This is the first Li-S model to also reproduce the characteristic overshoot in voltage at the beginning of charge, suggesting its cause is the increase in charge transfer resistance brought by Li2S precipitation
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