Italian Diaspora and Foreign Direct Investment: A Cliometric Perspective

Recent economic literature highlights that migrant networks help to overcome the informal barriers that exist in the international markets and boost international investment. Empirical studies on different countries confirm this prediction. This paper estimates (OLS-IV) an econometric model to study the impact of both emigration and immigration on Italy’s bilateral foreign direct investment (FDI). The main result is that only the Italian diaspora has a significant positive effect on Italy’s both inward and outward FDI. A theoretical framework, a profile of the diaspora and of immigration in Italy and some exemplary entrepreneurial histories help to interpret the econometric evidence.International Investments, Migrant Networks, Entrepreneurial Histories

Transnational social capital and FDI. Evidence from Italian associations worldwide

Emigrant associations abroad are structured nodes of social networks; they are manifestations of a transnational social capital. Italian associations are numerous, spread across several countries, in some cases they exist since the end of the nineteenth century, and may count on high numbers of members. Also, they are robustly tied to the home country. This paper assesses the effects of Italian associations abroad on the bilateral FDI between Italy and the countries of settlement of Italian diaspora. The main results are that these effects are positive and strongly significant, especially for the inward FDI and relatively to the countries with the oldest associations.international migration; FDI; Italy

Transnational social capital and FDI.Evidence from Italian associations worldwide

Emigrant associations abroad are structured nodes of social networks; they are manifestations of a transnational social capital. Italian associations are numerous, spread across several countries, in some cases they exist since the end of the nineteenth century, and may count on high numbers of members. Also, they are robustly tied to the home country. This paper assesses the effects of Italian associations abroad on the bilateral FDI between Italy and the countries of settlement of Italian diaspora. The main results are that these effects are positive and strongly significant, especially for the inward FDI and relatively to the countries with the oldest associationsinternational migration, FDI, Italy

Reduced Basis method for Isogeometric Analysis: application to structural problems

Isogeometric Analysis (IGA) is a computational methodology for the numerical approximation of Partial Differential Equations (PDEs). IGA is based on the isogeometric concept, for which the same basis functions, usually Non-Uniform Rational B-Splines (NURBS), are used both to represent the geometry and to approximate the unknown solutions of PDEs. Compared to the standard Finite Element method, NURBS-based IGA offers several advantages: ideally a direct interface with CAD tools, exact geometrical representation, simple refinement procedures, and smooth basis functions allowing to easily solve higher order problems, including structural shell problems. In these contexts, repeatedly solving a problem for a large set of geometric parameters might lead to high and eventually prohibitive computational cost. To cope with this problem, we consider in this work the Reduced Basis (RB) method for the solution of parameter dependent PDEs, specifically for which the NURBS representation of the computational domain is parameter dependent. RB refers to a technique that enables a rapid and reliable approximation of parametrized PDEs by constructing low dimensional approximation spaces. In this work, for the construction of the reduced spaces we adopt two different strategies, namely the Proper Orthogonal Decomposition and the greedy algorithm. In this thesis we combine RB and IGA for the efficient solution of parametrized problems for all the possible cases of NURBS geometrical parametrizations, which specifically include the NURBS control points, the weights, and both the control points and weights. In particular, we first focus on the solution of second order PDEs on parametrized lower dimensional manifolds, specifically surfaces in the three dimensional space. We consider geometrical parametrizations that entail a nonaffine dependence of the variational forms on the spatial coordinates and the geometric parameters. Thus, depending on the parametrization at hand and in order to ensure a suitable Offline/Online decomposition between the reduced order model construction and solution, we resort to the Empirical Interpolation Method (EIM) or the Matrix Discrete Empirical Interpolation Method (MDEIM), by comparing their performances. As application, we solve a class of benchmark structural problems modeled by Kirchoff-Love shells for which we consider NURBS geometric parametrizations and we apply the RB method to the solution of this class of fourth order PDEs. We highlight by means of numerical tests, the performance of the RB method applied to standard IGA approximation of parametrized shell geometries

Learning how to speak truth to power – comparing Ukrainian and Swiss foreign language curricula

Human Rights Education strives to empower learners to participate meaningfully in a democratic and sustainable society in which human rights are guaranteed for all. Foreign language education enables students to transcend borders, gives them an opportunity to share their views, ideas, and beliefs, and contributes to the development of critical thinking skills. It can thus endow students with a ‘voice’ to claim and defend their rights and learn to ‘speak truth to power’. This article explores if and how the intended foreign language curricula for lower secondary schools in Switzerland and Ukraine integrate human rights education. Drawing on the 2011 UN Declaration on Human Rights Education and Training as an analytical framework, the analysis reveals that ‘education for human rights’ is the best represented dimension in both contexts. Our results may serve as a springboard for exploring further opportunities to integrate human rights education and foreign language education

Relato de experiência da ação de proteção ao aleitamento materno

A Norma Brasileira de Comercialização de Alimentos para Lactentes e Crianças de Primeira Infância, Bicos, Chupetas e Mamadeiras (NBCAL) é uma lei responsável por regulamentar a comercialização dos alimentos e produtos destinados às crianças menores de três anos. Apesar de sua importância, essa lei enfrenta o desconhecimento pelos profissionais da saúde, além de ser violada, especialmente, pelas empresas desses produtos. O objetivo principal deste trabalho foi realizar um relato de experiência de uma ação de extensão que teve como foco a divulgação da NBCAL. A ação foi realizada em sala de videoconferência, contando com atividades de exposição teórica e com metodologias ativas, ocorrendo entre os dias 24 e 26 de agosto de 2021 (total de 8 horas). Participaram 48 estudantes e profissionais de diversas áreas da saúde. O nível de conhecimento dos participantes sobre aleitamento materno e o conceito da NBCAL aumentou de, em média, 5,4 e 3,8 pontos para 8 e 7,8 pontos, respectivamente. O evento pôde proporcionar conhecimento sobre a NBCAL, bem como alertar sobre diversas estratégias de marketing utilizadas pelas empresas de produtos infantis. Adicionalmente, foi possível explorar a promoção e a proteção do aleitamento materno

Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella

Aiming to combine the flexibility of Brucella lumazine synthase (BLS) to adapt different protein domains in a decameric structure and the capacity of BLS and flagellin to enhance the immunogenicity of peptides that are linked to their structure, we generated a chimeric protein (BLS-FliC131) by fusing flagellin from Salmonella in the N-termini of BLS. The obtained protein was recognized by anti-flagellin and anti-BLS antibodies, keeping the oligomerization capacity of BLS, without affecting the folding of the monomeric protein components determined by circular dichroism. Furthermore, the thermal stability of each fusion partner is conserved, indicating that the interactions that participate in its folding are not affected by the genetic fusion. Besides, either in vitro or in vivo using TLR5-deficient animals we could determine that BLS-FliC131 retains the capacity of triggering TLR5. The humoral response against BLS elicited by BLS-FliC131 was stronger than the one elicited by equimolar amounts of BLS + FliC. Since BLS scaffold allows the generation of hetero-decameric structures, we expect that flagellin oligomerization on this protein scaffold will generate a new vaccine platform with enhanced capacity to activate immune responsesFil: Hiriart, Yanina. Inmunova S.A; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Rossi, Andrés Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Biedma, Marina Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Errea, Agustina Juliana. Universidad Nacional de La Plata; Argentina. Universidad Nacional de La Plata; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Moreno, Griselda Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Cayet, D.. Universidad Nacional de La Plata; ArgentinaFil: Rinaldi, Jimena Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Blancá, Bruno Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Sirard, J.C.. Centre National de la Recherche Scientifique; FranciaFil: Goldbaum, Fernando Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Berguer, Paula Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Rumbo, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; Argentin

Performance of the pediatric index of mortality 2 (PIM-2) in cardiac and mixed intensive care units in a tertiary children's referral hospital in Italy

Background: Mortality rate of patients admitted to Intensive Care Units is a widely adopted outcome indicator. Because of large case-mix variability, comparisons of mortality rates must be adjusted for the severity of patient illness at admission. The Pediatric Index of Mortality 2 (PIM-2) has been widely adopted as a tool for adjusting mortality rate by patients' case mix. The objective of this study was to assess the performance of PIM-2 in children admitted to intensive care units after cardiac surgery, other surgery, or for other reasons. Methods: This was a prospective cohort study, conducted in a 607 inpatient-bed tertiary-care pediatric hospital in Italy, with three pediatric intensive care Units (PICUs) and one cardiac Unit (CICU). In 2009-11, all consecutive admissions to PICUs/CICU of children aged 0-16 years were included in the study. Discrimination and calibration measures were computed to assess PIM-2 performance. Multivariable logistic regression analysis was used to assess the association of patients' main reason for intensive care admission (cardiac-surgical, other-surgical, medical), age, Unit and year with observed mortality, adjusting for PIM-2 score. Results: PIM-2 data collection was completed for 91.2% of total PICUs/CICU patient admissions (2912), and for 94.8% of patients who died in PICUs/CICU (129). Overall observed mortality was 4.4% (95% CI, 3.7-5.2), compared to 6.4% (95% CI, 5.5-7.3) expected mortality. Standardised mortality ratio was 0.7 (95% CI: 0.6-0.8). PIM-2 discrimination was fair (area under the curve, 0.79; 95% CI: 0.75-0.83). Calibration was less satisfactory, mainly because of the over two-fold overprediction of deaths in the highest risk group (114.7 vs 53; p < 0.001), and particularly in cardiac-surgical patients. Multivariable logistic analysis showed that risk of death was significantly reduced in cardiac-surgical patients and in those aged 1 month to 12 years, independently from PIM-2. Conclusions: The children age distribution and the proportion of cardiac-surgical patients should be taken into account when interpreting SMRs estimated using the PIM-2 prediction model in different Units. A new calibration study of PIM-2 score might be needed, and more appropriate cardiac-focused risk-adjustment models should be developed. The role of age on risk of death needs to be further explored

DNA metabarcoding of forensic mycological samples

DNA metabarcoding and massive parallel sequencing are valuable molecular tools for the characterization of environmental samples. In forensic sciences, the analysis of the sample’s fungal population can be highly informative for the estimation of post-mortem interval, the ascertainment of deposition time, the identification of the cause of death, or the location of buried corpses. Unfortunately, metabarcoding data analysis often requires strong bioinformatic capabilities that are not widely available in forensic laboratories. The present paper describes the adoption of a user-friendly cloud-based application for the identification of fungi in typical forensic samples. The samples have also been analyzed through the QIIME pipeline, obtaining a relevant data concordance on top genus classification results (88%).The availability of a user-friendly application that can be run without command line activities will increase the popularity of metabarcoding fungal analysis in forensic samples