Behavioral Health among Asian American and Pacific Islanders: The Impact of Acculturation and Receipt of Behavioral Health Services on Depression and Anxiety

Behavioral health models improve access to mental health care by integrating psychology and medicine. While integrated care is supported among the general population, less research focuses on the model with Asian American and Pacific Islanders (AAPIs). AAPIs are low treatment-seeking due to various barriers (e.g., limited English proficiency, stigma, insurance) and acculturation stressors. Using hierarchical linear modeling, this study examined longitudinal depression (PHQ-9) and anxiety (GAD-7) growth trajectories among AAPIs within a behavioral health model and the moderating impact of acculturation and frequency of behavioral health visits. The best fitting model was from a sample who (N = 354; 71.5% female) met the following inclusion criteria: (a) AAPI, (b) over 18 years of age, (c) engaged in three or more behavioral health visits, (d) PHQ-9 and GAD-7 scores at three or more time points, (e) proxy acculturation data. The sample was 39% Vietnamese, mean age was 55.84 (SD = 16.92), and behavioral health visits ranged from 3 to 12. Depression and anxiety growth trajectories indicated significant cubic functions (PHQ-9, β30 = -.077, p \u3c .001; GAD-7, β30 = -.045, p \u3c .001). For depression, there was a non-significant moderating effect of acculturation (β11 = .163, p = .468, β21 = -.005, p = .931, β31 = -.001, p = .770), but significant effect of frequency of behavioral health visits (β12 = .252, p = .005, β22 = -.080, p = .004, β32 = .005, p = .010). For anxiety, there was a non-significant moderating effect of acculturation (β11 = .255, p = .148) and frequency of behavioral health visits (β12 = .126, p = .075) on instantaneous rate of change (i.e., slope). There was a non-significant moderating effect of acculturation (β21 = -.018, p = .687) but significant effect of frequency of behavioral health visits (β22 = -.044, p = .035) on change to the rate of change. Both moderators were non-significant at the cubic level (β31 = -.008, p = .822, β32 = .003, p = .057). Depression and anxiety outcomes among AAPIs improved within the behavioral health model. Moderation by acculturation and frequency of behavioral health visits varied

食品成分の抗体産生調節に関する研究

第1章 序論 第2章 食品成分のヒト型ハイブリドーマ抗体産生に及ぼす影響 第3章 豆乳による抗体産生増強 第4章 大豆外皮ヘミセルロース(SHH)による抗体産生増強 第5章 キトサンによる抗体産生増強 第6章 ポリカチオンの抗体産生増強 第7章 豆乳､SHH､キトサンのヒトリンパ球抗体産生増強 第8章 キトサン及びポリリジンによる抗体産生増強機作の検討 第9章 多糖類及びポリカチオンによるインターフェロン-β産生調節 第10章 総括Made available in DSpace on 2012-06-28T07:06:45Z (GMT). No. of bitstreams: 1 yamamoto.pdf: 14021882 bytes, checksum: b1f9157a518e59e5acdb37fe8a8ea3d2 (MD5) Previous issue date: 1992-09-21主1-参

The postural effects of yoked prisms

The goal of this project was to quantify the postural changes induced by yoked prisms after a period of adaptive wear between two groups, one sitting and reading while the other was continually walking. The project included 36 randomly selected subjects ranging in age from 21 to 28. Testing involved measurements to quantify the immediate and short term effects of vertical yoked prism wear on the center of balance as measured by the Chattex Balance System™. Our study noted immediate significant changes in body posture when prisms were first placed on subjects. After short time adaptation, both reading and walking groups showed a return to habitual posture with no difference in adaptation between groups. No significant rebound or after-effect of prism wear was measured immeidately after prims removal.

APC/C–Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs

AbstractIn vertebrates, unfertilized eggs are arrested at meiotic metaphase II (meta-II) by cytostatic factor (CSF), with Cdc2 activity maintained at a constant, high level. CSF is thought to suppress cyclin B degradation through the inhibition of the anaphase-promoting complex/cyclosome (APC/C)-Cdc20 while cyclin B synthesis continues in unfertilized eggs. Thus, it is a mystery how Cdc2 activity is kept constant during CSF arrest. Here, we show that the APC/C–Cdc20 can mediate cyclin B degradation in CSF-arrested Xenopus eggs and extracts, in such a way that when Cdc2 activity is elevated beyond a critical level, APC/C–Cdc20-dependent cyclin B degradation is activated and Cdc2 activity consequently declines to the critical level. This feedback control of Cdc2 activity is shown to be required for keeping Cdc2 activity constant during meta-II arrest. We have also shown that Mos/MAPK pathway is essential for preventing the cyclin B degradation from inactivating Cdc2 below the critical level required to sustain meta-II arrest. Our results indicate that under CSF arrest, Mos/MAPK activity suppresses cyclin B degradation, preventing Cdc2 activity from falling below normal meta-II levels, whereas activation of APC/C–Cdc20-mediated cyclin B degradation at elevated levels of Cdc2 activity prevents Cdc2 activity from reaching excessively high levels

Isolation of lipid-rich marine diatoms from the coastal waters of the Goto Islands, Japan

Five diatom strains were isolated from the coastal waters of Goto Islands and their fatty acid content and composition were evaluated. Fatty acid composition of the isolates showed a similar tendency, and fatty acids of 14:0, 16:0, and 16:1 (n-7) accounted for the majority, comprising 7.4 to 27.2% of the total, 3.8 to 37.1% of the total, and 15.7 to 59.6% of the total, respectively. In addition, most isolates contained polyunsaturated fatty acid of 20:5 (n-3) (eicosapentaenoic acid, EPA) and docosahexaenoic acid (DHA), which are essential fatty acids in marine organisms. Among the isolates, a pennate diatom cf. Diploneis sp. contained the highest EPA. The potential of the pennate diatom for aquaculture feed, and the ecological significance of EPA and DHA content of diatoms in marine food webs in the vicinity of Goto Islands are briefly discussed.departmental bulletin pape

相互行為における聞き手反応としての「うん／はい」の使い分け : 「丁寧さ」とは異なる観点から

早稲田大学Waseda University本研究は「うん」「はい」に代表される「聞き手の短い反応」を対象とし，その使い分けを明らかにするものである。これまでの日本語学・日本語教育における研究では，「うん」と「はい」の違いは基本的には「丁寧さ」のみが異なるものとして提示されてきた。しかしながら，筆者が「日本語話し言葉コーパス（CSJ）」のインタビュー場面のデータを対象とし，分析を行ったところ，「丁寧さ」とは異なる基準で両者が使い分けられている可能性が示唆された。本稿では，会話分析（Conversation Analysis）の立場から，インタビュイー（説明者）が自己開始修復を用いて「聞き手に向けて特別に説明を差し挟み，修復の操作が完了する」とわかる位置において，聞き手はそれまでの反応とは差異化した形で反応をすることを例証する。This study highlights usage differences between un and hai, two recipient response tokens available in the Japanese language. Prior research in the fields of Japanese language and Japanese language education suggests that the difference in usage between the two response tokens is merely one of politeness. However, analysis by the author of the Corpus of Spontaneous Japanese (CSJ), a collection of Japanese conversations, indicates that recipients may also distinguish the use of un and hai based on a standard other than politeness. From the viewpoint of conversation analysis, this paper illustrates that when speakers use self-initiated repair during an explanation to supplement special information for recipients, the latter will switch to a different response token at the end of the repair sequence, thus differentiating between the tokens on the basis of context