Three-dimensional carbon nanotube yarn based solid state solar cells with multiple sensitizers exhibit high energy conversion efficiency

Fiber-type dye sensitized solar cells that are non-metallic, flexible, and thread-like in structure have many potential military and functional textile applications. With the use of quantum dots (QD), exciton transfer facilitators (Phenyl-C61-butyric acid methyl ester-PCBM) and Poly(3-hexylthiophene-2,5-diyl-P3HT), and careful preparation of the TiO2 oxide layer deposited on the carbon fiber working electrode, an optimized efficiency of 7.6% was obtained. Carbon nanotube yarn (CNTY) was used to prepare both the working and counter electrodes of the fabricated cells. TiCl4 annealing of the TiO2 layer was carried out and the resulting oxide layer morphology was found to be very uniform. The quantum dots, cadmium sulfide (CdS) and cadmium selenide (CdSe), were deposited directly onto the surface of the nanoporous oxide layer using chemical bath deposition (CBD). Also, the P3HT and PCBM were applied and deposited via CBD on the working electrode as a bulk heterojunction material. Potentiometric characterization of the prepared cells performed at different cell lengths and showed that the maximum efficiency was obtained for cells approximately 3.5 cm in length. Photovoltaic performance of these solid state three dimensional cells was also carried out for different cell configurations

Advanced cotton fibers exhibit efficient photocatalytic self-cleaning and antimicrobial activity

Functional cotton fibers have a wide range of applications in domestic, commercial, and military settings, and so enhancing the properties of these materials can yield substantial benefits. Herein, we report the creation of functional fibers that are self-cleaning, anti-microbial, and protective against UV radiation. A uniform, and high surface area films of TiO2 were deposited on cotton fibers and gold/silver nanoparticles were directly incorporated on the nanostructured TiO2 surface. The synthetic method is simple and the produced TiO2 film is homogenous and the nanoparticles were shown to be effectively distributed on the surface using a simple photocatalytic reduction method. The Ag/Au-TiO2 coated fibers was morphologically characterized using atomic force microscopy (AFM) and scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS), and the self-cleaning properties of noble metal nanoparticle/TiO2 coated fibers were demonstrated by repeated staining followed by exposure to simulated solar light. The 1 mM Ag-TiO2 coated fabric was observed to have the largest improvement in rate of stain extinction compared to the untreated fibers with a methylene blue stain, and the 1 mM Au-TiO2 coated fibers were observed to have the largest improvement versus untreated fibers when stained with Congo red. The fibers maintained consistent photocatalytic activity over multiple cycles, and the resistance of the Ag/Au-TiO2 coated cotton to degradation was verified using Fourier transform infrared spectroscopy (FTIR). An efficient anti-microbial activity of the fibers was confirmed by exposure of the fibers to bacterial culture (Escherichia Coli) and direct observation of antimicrobial activity

Recipient Preparation and Mixed Germ Cell Isolation for Spermatogonial Stem Cell Transplantation in Domestic Cats

The loss of genetic diversity poses a serious threat to the conservation of endangered species, including wild felids. We are attempting to develop spermatogonial stem cell transplantation in the cat as a tool to preserve and propagate male germ-plasm from genetically valuable animals, be they threatened wild species or lines of cats used as models for inherited diseases. In this study, we investigated the use of local external beam radiation treatment to deplete the endogenous germ cells of male domestic cats, a step necessary to prepare them for use as recipients for transplantation. Testes of 5-month-old domestic cats were irradiated with a fractionated dose of 3 Gy per fraction for 3 consecutive days. These cats were castrated at 2, 4, 8, 16, and 32 weeks posttreatment, and progress of spermatogenesis was evaluated histologically and compared against age-matched controls. Even at the latest time points, less than 10% of tubules contained germ cells at any stage of meiosis, showing the efficacy of this protocol. In addition, male germ cells were isolated from the testes of domestic cats using a 2-step enzymatic dissociation to establish a protocol for the preparation of donor cells. The presence and viability of spermatogonia within this population were demonstrated by successful transplantation into, and colonization of, mouse seminiferous tubules. The success of these protocols provides a foundation to perform spermatogonial stem cell transplantation in the domestic cat.Supported in part by grants from the Morris Animal Foundation (A.J.T.), Cornell Universitys Feline Health Center (A.J.T.), and the BK21 Fellowship program between Seoul National University and Cornell University (Y.K.). We thank Professor Ralph Brinster of the University of Pennsylvania School of Veterinary Medicine for his support of the feline spermatogonial stem cell transplantation into the mouse, which was performed in his laboratory. We thank Colonial Veterinary Hospital, Ithaca, NY, and Dr Leslie D. Appel of Shelter Outreach Services for providing testis specimens from routine castrations. We also thank Drs Blaise P. Burke and Rodney L. Page for their assistance with the external beam radiation treatment, as well as Jean Spencer and Laura Hobbs for their technical assistance

Patient and clinician-reported experiences of using electronic patient reported outcome measures (ePROMs) as part of routine cancer care

Abstract Background Cancer and its treatment can have significant impacts on health status, quality of life and functioning of patients. Direct information from patients regarding these aspects can be collected via electronic platforms in the form of electronic Patient Reported Outcome Measures (ePROMs). Research has shown that the use of ePROMS in cancer care leads to improved communication, better symptom control, prolonged survival and a reduction in hospital admissions and emergency department attendance. Acceptability and feasibility of routine ePROM collection has been reported by both patients and clinicians but to date their use has predominantly been limited to clinical trials. MyChristie-MyHealth is an initiative from a UK comprehensive cancer centre The Christie NHS Foundation Trust which incorporates the regular collection of ePROMs into routine cancer care. This study, carried out as part of a service evaluation, explores patient and clinician experiences of using the MyChristie-MyHealth ePROMs service. Results 100 patients with lung and head and neck cancers completed a Patient Reported Experience questionnaire. All patients reported that MyChristie-MyHealth was easy to understand and, almost all found it timely to complete and easy to follow. Most patients (82%) reported it improved their communication with their oncology team and helped them to feel more involved with their care (88%). A large proportion of clinicians (8/11) felt ePROMs helped communication with their patients and over half (6/10) felt they led to consultations being more patient focused. Clinicians also felt that the use of ePROMs resulted in patients being more engaged in consultations (7/11) and their cancer care in general (5/11). Five clinicians reported that the use of ePROMs altered their clinical decision making. Conclusions Regular ePROMs collection as part of routine cancer care is acceptable to both patients and clinicians. Both patients and clinicians feel their use improved communication and increased the feeling of patient involvement with their care. Further work is needed to explore the experiences of patients that did not complete the ePROMs as part of the initiative and to continue to optimize the service for both patients and clinicians