491 research outputs found

    Growth and subsidence of carbonate platforms: numerical modelling and application to the Dolomites, Italy

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    The phenomenon of subsidence induced by the growth of carbonate platforms has been investigated with the aid of numerical modelling. The research aimed to quantify the relative contribution of this process in the creation of the accommodation space required to pile up thick neritic bodies. We analysed two end-member deformation styles, namely the elastic behaviour of the lithosphere when locally loaded and the plastic-like reaction of a sedimentary succession underlying a growing carbonate buildup. The former process, analysed using a modified flexural model, generates a regional subsidence. In contrast, the latter process, simulated by considering the compaction occurring in soft sediments, generates a local subsidence. We attempted to quantify the amount and distribution of subsidence occurring below and surrounding an isolated platform and in the adjacent basin. The major parameters playing a role in the process are discussed in detail. The model is then applied to the Late Anisian-Early Ladinian generation of carbonate platforms of the Dolomites, Northern Italy, where they are spectacularly exposed. Taking also into account the Tertiary shortening that occurred in the area, both local and regional subsidence contributions of major platform bodies have been calculated aimed at a reconstruction of the map of the induced subsidence. A major outcome of this study is that the accommodation space, that allowed the accumulation of very thick shallow-water carbonate successions in the Dolomites, was only partially due to lithospheric stretching while the contribution given by the 'local' overload is as high as 20-40% of the total subsidence. Our results also shed some light on the water-depth problem of the Triassic basins as well as on the basin-depth to platform-thickness relationships

    Fostering collaborative research for rare genetic disease: The example of Niemann-Pick type C disease

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    Rare disease represents one of the most significant issues facing the medical community and health care providers worldwide, yet the majority of these disorders never emerge from their obscurity, drawing little attention from the medical community or the pharmaceutical industry. The challenge therefore is how best to mobilize rare disease stakeholders to enhance basic, translational and clinical research to advance understanding of pathogenesis and accelerate therapy development. Here we describe a rare, fatal brain disorder known as Niemann-Pick type C (NPC) and an innovative research collaborative known as Support of Accelerated Research for NPC (SOAR-NPC) which illustrates one pathway through which knowledge of a rare disease and its possible treatments are being successfully advanced. Use of the “SOAR” mechanism, we believe, offers a blueprint for similar advancement for many other rare disorders

    Treating agricultural non-point source pollutants using periphyton biofilms and biomass volarization

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    Untreated domestic wastewater and agricultural runoff are emerging as a potent cause of non-point source (NPS) pollutants which are a major threat to aquatic ecosystems. Periphyton biofilm-based technologies due to their high growth rate, energy efficiency and low input costs offer promising solutions for controlling nutrient pollution in agricultural systems. In this study we employed periphyton floway to treat NPS pollution from the agricultural watershed. The process performance of outdoor single pass algae floway (AFW) was evaluated. Steady state average biomass concentration of 11.73 g

    Obesity as a social phenomenon: A narrative review

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    BACKGROUND: obesity is one of the most prevalent diseases all over the world. Because of its high social impact, the broadest possible approach on several levels - and not limited only to clinical aspect - is needed to better understand and face the challenges obesity poses to public health. OBJECTIVES: to analyse, through the main evidence, the so- cial impact of weight excess in the general population and the actions aimed at mitigating its negative effects. DESIGN: narrative review. SETTING: data obtained from the sources included in the study were gathered and analyzed in five macroareas: Health Inequality, Society, Work, Impact on Social Medicine (focused on the Italian model), and Social Costs. RESULTS: each category showed a bilateral relationship with obesity having a significant impact for the community. CONCLUSIONS: for each field, various actions should be taken at institutional level. Many recommendations and actions have already been taken worldwide, but they alone seem to be not enough. This work points out that, in order to combat obesity and bring about a slowdown of this pandemic, the en- tire scientific community and institutions must work together to identify and design programmes that are truly effective

    Field-testing of the rapid assessment of disability questionnaire

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    The Rapid Assessment of Disability (RAD) questionnaire measures the magnitude and impact of disability and aims to inform the design of disability inclusive development programs. This paper reports the psychometric evaluation of the RAD

    Health Management in Italian prisons during Covid 19 OUTBREAK: a focus on the second and third wave

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    The SARS-CoV-2 spread is a threatening and challenging issue for correctional systems worldwide because of many factors, particularly overcrowding and of the intrinsic characteristics of the population. The prevention measures adopted by the Italian Government were aimed to protect and preserve both inmates’ and prison workers’ health. The present study aimed to evaluate the efficacy of the adopted strategies. Methods: Data regarding Italian prisons’ occupation and prisoners’ population from January 2019 to June 2021, as well as the cumulative weekly increase of confirmed cases and the number of doses of vaccine administered among the population of inmates, the prison workers, and Italian population from November 2020 to the end of June 2021, were collected. Results: Prisons’ occupation dropped from 120% to 106% after the beginning of the pandemics. The confirmed cases between inmates were consistently lower than among the Italian population and prison workers. A time-series chart showed a time lag of one week between the peaks of the different population. Conclusions: The containing strategies adopted by the Italian correctional system have proved their effectiveness in terms of the prevention and protection of both inmate and staff health

    Biodiesel production through algal cultivation in urban wastewater using algal floway

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    The aim of this work was to study algal floway (AFW) to treat urban wastewater and to evaluate biomass productivity, lipid contents and biodiesel production. The results indicated the seasonal average algae productivity of 34.83 g dry weight m2 d−1 with a nutrient removal rate of 2.52 g m2 d−1N and 1.25 g m2 d−1P while the lipid content ranged between 14 and 22% of dry cell weight with the highest lipid productivity of 9.29 g m−2 d−1 during summer. Biodiesel quality was superior during summer with high centane number and cold filter plugging point values. High eicosapentaenoic acid content was found during winter growth cycles. AFW algae community was dominated by pennate diatoms during all growing seasons. This study is one of its kinds in Indian wastewaters and it provides fundamental information for further optimization and use of AFW to treat domestic wastewater and to produce algae biofuel feedstock
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