73 research outputs found

    Non-wage benefits, corporate ownership and firm performance in post-communist economies: evidence from Ukraine

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    International audienceThe economic reforms in the transition economies of Central and Eastern Europe have fundamentally reshaped ownership and governance of economic production, notably through the privatization of former state-owned enterprises. These reforms were expected to transform management practices by displacing ‘cradle-to-grave’ welfare arrangements administered by state-owned enterprises. Using data drawn from two large samples of Ukrainian establishments, we investigate, in two different time points, the relationship between non-wage benefits and firm performance during the period of transition to a market economy (1994–2004). We found that non-wage benefits continued to be a critical feature of HRM practices in Ukraine during this period, and were positively associated with firm performance

    hArtes: Hardware-Software Codesign for Heterogeneous Multicore Platforms

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    Developing heterogeneous multicore platforms requires choosing the best hardware configuration for mapping the application, and modifying that application so that different parts execute on the most appropriate hardware component. The hArtes toolchain provides the option of automatic or semi-automatic support for this mapping. During test and validation on several computation-intensive applications, hArtes achieved substantial speedups and drastically reduced development times

    Proton and photon radiotherapy in stage III NSCLC:Effects on hematological toxicity and adjuvant immune therapy

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    Background and purpose: Concurrent chemo-radiotherapy (CCRT) followed by adjuvant durvalumab is standard-of-care for fit patients with unresectable stage III NSCLC. Intensity modulated proton therapy (IMPT) results in different doses to organs than intensity modulated photon therapy (IMRT). We investigated whether IMPT compared to IMRT reduce hematological toxicity and whether it affects durvalumab treatment. Materials and methods: Prospectively collected series of consecutive patients with stage III NSCLC receiving CCRT between 06.16 and 12.22 (staged with FDG-PET-CT and brain imaging) were retrospectively analyzed. The primary endpoint was the incidence of lymphopenia grade ≄ 3 in IMPT vs IMRT treated patients. Results: 271 patients were enrolled (IMPT: n = 71, IMRT: n = 200) in four centers. All patients received platinum-based chemotherapy. Median age: 66 years, 58 % were male, 36 % had squamous NSCLC. The incidence of lymphopenia grade ≄ 3 during CCRT was 67 % and 47 % in the IMRT and IMPT group, respectively (OR 2.2, 95 % CI: 1.0–4.9, P = 0.03). The incidence of anemia grade ≄ 3 during CCRT was 26 % and 9 % in the IMRT and IMPT group respectively (OR = 4.9, 95 % CI: 1.9–12.6, P = 0.001). IMPT was associated with a lower rate of Performance Status (PS) ≄ 2 at day 21 and 42 after CCRT (13 % vs. 26 %, P = 0.04, and 24 % vs. 39 %, P = 0.02). Patients treated with IMPT had a higher probability of receiving adjuvant durvalumab (74 % vs. 52 %, OR 0.35, 95 % CI: 0.16–0.79, P = 0.01). Conclusion: IMPT was associated with a lower incidence of severe lymphopenia and anemia, better PS after CCRT and a higher probability of receiving adjuvant durvalumab.</p

    A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: a real- world experience

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    We addressed trastuzumab emtansine (T-DM1) e cacy in HER2+ metastatic breast cancer patients treated in real-world practice, and its activity in pertuzumab- pretreated patients. We conducted a retrospective, observational study involving 23 cancer centres, and 250 patients. Survival data were analyzed by Kaplan Meier curves and log rank test. Factors testing signi cant in univariate analysis were tested in multivariate models. Median follow-up was 15 months and median T-DM1 treatment-length 4 months. Response rate was 41.6%, clinical bene t 60.9%. Median progression-free and median overall survival were 6 and 20 months, respectively. Overall, no di erences emerged by pertuzumab pretreatment, with median progression-free and median overall survival of 4 and 17 months in pertuzumab- pretreated (p=0.13), and 6 and 22 months in pertuzumab-naïve patients (p=0.27). Patients who received second-line T-DM1 had median progression-free and median overall survival of 3 and 12 months (p=0.0001) if pertuzumab-pretreated, and 8 and 26 months if pertuzumab-naïve (p=0.06). In contrast, in third-line and beyond, median progression-free and median overall survival were 16 and 18 months in pertuzumab- pretreated (p=0.05) and 6 and 17 months in pertuzumab-naïve patients (p=0.30). In multivariate analysis, lower ECOG performance status was associated with progression-free survival bene t (p<0.0001), while overall survival was positively a ected by lower ECOG PS (p<0.0001), absence of brain metastases (p 0.05), and clinical bene t (p<0.0001). Our results are comparable with those from randomized trials. Further studies are warranted to con rm and interpret our data on apparently lower T-DM1 e cacy when given as second-line treatment after pertuzumab, and on the optimal sequence order

    The role of proximity to local and global citizens in stakeholders' moral recognition of corporate social responsibility

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    International audienceThe aim of this paper is to explore the effects of social proximity (defined by national and global identities) and geographic proximity (one's own nation or foreign nations) on the moral recognition of corporate social responsibility (CSR). To achieve this objective we draw upon moral decision-making and social identity theory. We test our hypotheses using a homogeneous (in terms of age and education) sample from China and France (Study 1, N = 369) and replicate the study with a demographically heterogeneous sample from the United Kingdom (Study 2, N = 207). The results suggest that national and global identities positively affect citizens' moral recognition of CSR; and global identity offsets the negative effect of geographic distance on moral recognition of CSR. These results indicate that global identity makes individuals care more about CSR abroad than they would without this identity

    A Race To The Bottom? Globalisation, International Trade And The Evolution Of Australian Federal Labour Standards 1979 To 2000

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    The primary objective of this study is to intervene in the trade-labour rights debate by quantifying Federal labour standards in Australia in 1979 and 2000 and by capturing and explaining key shifts in the legal protection accorded to employees over this period. In order to achieve this aim, non-parametric absolute indexes are generated for 1979 and 2000 to measure the strength of labour standards and associated changes over time. The numerical results suggest that in this period, during which the exposure of the Australian economy to global forces was greatly increased, two of the ten standards measured, workers' compensation and collective bargaining, diminished while the indexes for equal employment opportunity/ employment equity, unjust discharge, occupational health and safety and large-scale layoffs increased. The empirical results are then explained by applying Karl Polanyi's theoretical framework. The paper concludes by making two key observations: first, claims suggesting that heightened levels of international trade and investment are undermining labour standards seem to be premature and second, the reduction in Labour's market power, that occurred during the period investigated, has the potential to adversely affect the overall level of social protection in Australia

    Sorry, could you repeat the question? Exploring video‐interview recruitment practice in HRM

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    International audienceHRM has embraced video interviewing through verbal computer‐mediated communication (VCMC) technology. However, empirical research in recruitment remains scant. Drawing on communication theories to analyse data from three studies, we present a conceptual framework explaining VCMC adoption and practice. We argue that VCMC technology has a larger effect on recruitment and selection outcomes than presumed. We broaden signalling theory to video recruitment and posit that interaction effects due to characteristics of the technology and a candidate's personality may affect recruitment outcomes. We also broaden media richness theory by uncovering memory effects arising from multiple interview modes. HR managers should be mindful of these and others limitations highlighted in the study before fully embracing this technology
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