Monte Carlo determination of the critical coupling in ϕ24\phi^4_2 theory

We use lattice formulation of $\phi^4$ theory in order to investigate non--perturbative features of its continuum limit in two dimensions. In particular, by means of Monte Carlo calculations, we obtain the critical coupling constant $g/\mu^2$ in the continuum, where $g$ is the {\em unrenormalised} coupling. Our final result is $g/\mu^2=11.15(6)(3)$.Comment: Version published on Phys. Rev. D. We added a reference and modified a couple of sentence

Transient obscuration event captured in NGC 3227: I. Continuum model for the broadband spectral energy distribution

From Swift monitoring of a sample of active galactic nuclei (AGN) we found a transient X-ray obscuration event in Seyfert-1 galaxy NGC 3227, and thus triggered our joint XMM-Newton, NuSTAR, and Hubble Space Telescope (HST) observations to study this event. Here in the first paper of our series we present the broadband continuum modelling of the spectral energy distribution (SED) for NGC 3227, extending from near infrared (NIR) to hard X-rays. We use our new spectra taken with XMM-Newton, NuSTAR, and HST/COS in 2019, together with archival unobscured XMM-Newton, NuSTAR, and HST/STIS data, in order to disentangle various spectral components of NGC 3227 and recover the underlying continuum. We find the observed NIR-optical-UV continuum is explained well by an accretion disk blackbody component (Tmax = 10 eV), which is internally reddened by E(B-V) = 0.45 with a Small Magellanic Cloud (SMC) extinction law. We derive the inner radius (12 Rg) and the accretion rate (0.1 solar mass per year) of the disk by modelling the thermal disk emission. The internal reddening in NGC 3227 is most likely associated with outflows from the dusty AGN torus. In addition, an unreddened continuum component is also evident, which likely arises from scattered radiation, associated with the extended narrow-line region (NLR) of NGC 3227. The extreme ultraviolet (EUV) continuum, and the 'soft X-ray excess', can be explained with a 'warm Comptonisation' component. The hard X-rays are consistent with a power-law and a neutral reflection component. The intrinsic bolometric luminosity of the AGN in NGC 3227 is about 2.2e+43 erg/s in 2019, corresponding to 3% Eddington luminosity. Our continuum modelling of the new triggered data of NGC 3227 requires the presence of a new obscuring gas with column density NH = 5e+22 cm^-2, partially covering the X-ray source (Cf = 0.6).Peer ReviewedPostprint (author's final draft

Atmospheric monitoring in the mm and sub-mm bands for cosmological observations: CASPER2

Cosmological observations from ground at millimetre and sub-millimetre wavelengths are affected by atmospheric absorption and consequent emission. The low and high frequency (sky noise) fluctuations of atmospheric performance imply careful observational strategies and/or instrument technical solutions. Measurements of atmospheric emission spectra are necessary for accurate calibration procedures as well as for site testing statistics. CASPER2, an instrument to explore the 90-450 GHz (3-15 1/cm) spectral region, was developed and verified its operation in the Alps. A Martin-Puplett Interferometer (MPI) operates comparing sky radiation, coming from a field of view (fov) of 28 arcminutes (FWHM) collected by a 62-cm in diameter Pressman-Camichel telescope, with a reference source. The two output ports of the interferometer are detected by two bolometers cooled down to 300 mK inside a wet cryostat. Three different and complementary interferometric techniques can be performed with CASPER2: Amplitude Modulation (AM), Fast-Scan (FS) and Phase Modulation (PM). An altazimuthal mount allows the sky pointing, possibly co-alligned to the optical axis of the 2.6-m in diameter telescope of MITO (Millimetre and Infrared Testagrigia Observatory, Italy). Optimal timescale to average acquired spectra is inferred by Allan variance analysis at 5 fiducial frequencies. We present the motivation for and design of the atmospheric spectrometer CASPER2. The adopted procedure to calibrate the instrument and preliminary performance of the instrument are described. Instrument capabilities were checked during the summer observational campaign at MITO in July 2010 by measuring atmospheric emission spectra with the three different procedures.Comment: 11 pages, 9 figures, 2 tables, Accepted for publication in MNRA

Does the disk in the hard state of XTE J1752-223 extend to the innermost stable circular orbit?

The accreting black hole binary XTE J1752–223 was observed in a stable hard state for 25 days by the Rossi X-ray Timing Explorer (RXTE), yielding a 3–140 keV spectrum of unprecedented statistical quality. Its published model required a single-Comptonization spectrum reflecting from a disk close to the innermost stable circular orbit. We studied that model as well as a number of other single-Comptonization models (yielding similarly low inner radii), but found they violate a number of basic physical constraints, e.g., their compactness is much above the maximum allowed by pair equilibrium. We also studied the contemporaneous 0.55–6 keV spectrum from the Swift/X-ray Telescope and found it well fitted by an absorbed power law and a disk blackbody with the innermost temperature of 0.1 keV. The normalization of the disk blackbody corresponds to an inner radius of ¿20 gravitational radii and its temperature, to irradiation of the truncated disk by a hot inner flow. We have also developed a Comptonization/ reflection model including the disk irradiation and intrinsic dissipation, but found that it does not yield any satisfactory fits. On the other hand, we found that the ¿10 keV band from RXTE is much better fitted by a reflection from a disk with the inner radius ¿100 gravitational radii, which model then underpredicts the spectrum at >10 keV by <10%. We argue that the most plausible explanation of the above results is inhomogeneity of the source, with the local spectra hardening with the decreasing radius. Our results support the presence of a complex Comptonization region and a large disk truncation radius in this sourcePostprint (author's final draft

Coeliac Disease and Mast Cells

Over the last decades, there has been an impressive progress in our understanding of coeliac disease pathogenesis and it has become clear that the disorder is the final result of complex interactions of environmental, genetic, and immunological factors. Coeliac disease is now considered a prototype of T-cell-mediated disease characterized by loss of tolerance to dietary gluten and the targeted killing of enterocytes by T-cell receptor \u3b1\u3b2 intraepithelial lymphocytes. Accumulating evidence, however, indicates that the induction of a gluten-specific T helper-1 response must be preceded by the activation of the innate immune system. Mast cells are key players of the innate immune response and contribute to the pathogenesis of a multitude of diseases. Here, we review the results of studies aimed at investigating the role of mast cells in the pathogenesis of coeliac disease, showing that these cells increase in number during the progression of the disease and contribute to define a pro-inflammatory microenvironment

Supplementary material for the article: Popovic, M.; Mazzega, E.; Toffoletto, B.; de Marco, A. Isolation of Anti-Extra-Cellular Vesicle Single-Domain Antibodies by Direct Panning on Vesicle-Enriched Fractions. Microbial cell factories 2018, 17 (1), 6. https://doi.org/10.1186/s12934-017-0856-9

Supplementary material for: [https://doi.org/10.1186/s12934-017-0856-9]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2069