7,687 research outputs found
Reporting errors in infectious disease outbreaks, with an application to Pandemic Influenza A/H1N1
Orbital Motion and Magnetic Activity in Close Binaries and Planetary Systems
The connection between orbital period variation and magnetic activity cyclic behaviour in close binaries with late-type components is addressed by discussing recent observational studies of Algols, RS CVn's, W UMa's and CVs. A theoretical model based on the Applegate's mechanism seems capable of explaining the observed orbital period modulation in terms of cyclic changes of a gravitational quadrupole moment induced by a magnetic activity cycle affecting one of the binary components. In such a case, the study of orbital period modulations offers a promising tool to investigate hydromagnetic dynamos operating in the interior of active stars, in particular, to address the fundamental question of the interaction between rotation and magnetic fields in nonlinear dynamo regimes. Moreover, interesting applications to planetary systems with a magnetically active central star are discussed
Decision boundaries using Bayes factors: the case of cloud masks
We assess the use of an approximation to the Bayes factor for objectively assessing spatial segmentation models. The Bayes factor allows us to automatically determine thresholds, in multidimensional feature space, for such objectives as cloud mask definition. We compare our results with a cloud map currently provided as a data product
Sensor-based early activity recognition inside buildings to support energy and comfort management systems
Building Energy and Comfort Management (BECM) systems have the potential to considerably reduce costs related to energy consumption and improve the efficiency of resource exploitation, by implementing strategies for resource management and control and policies for Demand-Side Management (DSM). One of the main requirements for such systems is to be able to adapt their management decisions to the usersâ specific habits and preferences, even when they change over time. This feature is fundamental to prevent usersâ disaffection and the gradual abandonment of the system. In this paper, a sensor-based system for analysis of user habits and early detection and prediction of user activities is presented. To improve the resulting accuracy, the system incorporates statistics related to other relevant external conditions that have been observed to be correlated (e.g., time of the day). Performance evaluation on a real use case proves that the proposed system enables early recognition of activities after only 10 sensor events with an accuracy of 81%. Furthermore, the correlation between activities can be used to predict the next activity with an accuracy of about 60%
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Determining the dynamics of influenza transmission by age
Background: It is widely accepted that influenza transmission dynamics vary by age; however methods to quantify the reproductive number by age group are limited. We introduce a simple method to estimate the reproductive number by modifying the method originally proposed by Wallinga and Teunis and using existing information on contact patterns between age groups. We additionally perform a sensitivity analysis to determine the potential impact of differential healthcare seeking patterns by age. We illustrate this method using data from the 2009 H1N1 Influenza pandemic in Gauteng Province, South Africa. Results: Our results are consistent with others in showing decreased transmission with age. We show that results can change markedly when we make the account for differential healthcare seeking behaviors by age. Conclusions: We show substantial heterogeneity in transmission by age group during the Influenza A H1N1 pandemic in South Africa. This information can greatly assist in targeting interventions and implementing social distancing measures
Estimating the reproductive number in the presence of spatial heterogeneity of transmission patterns
Background: Estimates of parameters for disease transmission in large-scale infectious disease outbreaks are often obtained to represent large groups of people, providing an average over a potentially very diverse area. For control measures to be more effective, a measure of the heterogeneity of the parameters is desirable. Methods: We propose a novel extension of a network-based approach to estimating the reproductive number. With this we can incorporate spatial and/or demographic information through a similarity matrix. We apply this to the 2009 Influenza pandemic in South Africa to understand the spatial variability across provinces. We explore the use of five similarity matrices to illustrate their impact on the subsequent epidemic parameter estimates. Results: When treating South Africa as a single entity with homogeneous transmission characteristics across the country, the basic reproductive number, R0, (and imputation range) is 1.33 (1.31, 1.36). When fitting a new model for each province with no inter-province connections this estimate varies little (1.23-1.37). Using the proposed method with any of the four similarity measures yields an overall R0 that varies little across the four new models (1.33 to 1.34). However, when allowed to vary across provinces, the estimated R0 is greater than one consistently in only two of the nine provinces, the most densely populated provinces of Gauteng and Western Cape. Conclusions: Our results suggest that the spatial heterogeneity of influenza transmission was compelling in South Africa during the 2009 pandemic. This variability makes a qualitative difference in our understanding of the epidemic. While the cause of this fluctuation might be partially due to reporting differences, there is substantial evidence to warrant further investigation
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