924 research outputs found
Civil Society Generating Innovation: Co-operative and Associative Housing
This research was undertaken thanks in part to the financial support of the Canada Research Chairs Program, SSHRC
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Direct Fabrication of Metal Orthopedic Implants Using Electron Beam Melting Technology
Metal orthopedic implants have been used for many decades with great success.
Replacement joints and plates for bone fractures are usually made from titanium, cobaltchromium or stainless steel. Through recent advancements in biomodeling, custom orthopedic
implants can be designed. However, fabrication of these custom implants can be prohibitively
expensive with traditional processes. With the introduction of Electron Beam Melting (EBM),
direct fabrication of fully dense metal components is possible. In this paper, the development of
titanium for the EBM-process will be discussed, and direct fabrication of custom designed
orthopedic implants made out of steel and titanium will be demonstrated.Mechanical Engineerin
An overview of JPEG 2000
JPEG-2000 is an emerging standard for still image compression. This paper provides a brief history of the JPEG-2000 standardization process, an overview of the standard, and some description of the capabilities provided by the standard. Part I of the JPEG-2000 standard specifies the minimum compliant decoder, while Part II describes optional, value-added extensions. Although the standard specifies only the decoder and bitstream syntax, in this paper we describe JPEG-2000 from the point of view of encoding. We take this approach, as we believe it is more amenable to a compact description more easily understood by most readers.
Le logement coopeĢratif et associatif comme innovation sociale eĢmanant de la socieĢteĢ civile
Communication au 25e CongreĢs international du CIRIEC, Palais des CongreĢs de Lyon, 27 et 28 septembre 2004.Le logement communautaire (coopeĢratif et associatif) apparaiĢt au QueĢbec au tournant des anneĢes 1970 dans un contexte de transformation du monde urbain, d'eĢmergence de nouveaux besoins en matieĢre de logement et de fleĢchissement des politiques gouvernementales en matieĢre d'habitat. Il s'agit d'une histoire joueĢe par diffeĢrents acteurs sociaux, qui s'entendront sur un programme de deĢveloppement de l'habitat communautaire en reĢponse aĢ des attentes en relative convergence. Les traits particuliers du logement communautaire proviennent aĢ la fois des apprentissages des geĢneĢrations preĢceĢdentes de logement social, et des aspirations nouvelles qui se font jour dans les mouvements de citoyens. NeĢcessitant dāimportants moyens de financement pour se deĢvelopper, le mode de fonctionnement du logement communautaire est eĢgalement en partie conditionneĢ par les rapports quāil entretient avec lāEĢtat, les institutions financieĢres et le marcheĢ. Les ambitions des citoyens se conjuguent avec celles des politiques dāhabitation, dessinant un compromis entre les caracteĢristiques de la forme associative et les objectifs de la politique de logement social.
Les politiques publiques viennent reĢpondre aĢ des besoins concrets de la population. Lorsque les reĢactions gouvernementales se font attendre, les citoyens ont appris aĢ revendiquer la creĢation de ces politiques. Les interventions du milieu communautaire en habitation ont beaucoup eĢvolueĢ depuis maintenant 30 ans, passant de la revendication d'interventions publiques aĢ de lāinnovation par des programmes d'aide aux initiatives locales. Le milieu communautaire est alleĢ plus loin en neĢgociant certains parameĢtres des programmes et meĢme, en eĢlaborant et en proposant des programmes de son cru.
Dans ce court exposeĢ, nous expliquerons dāabord comment les mouvements de citoyens et les initiatives quāils ont deĢveloppeĢes ont contribueĢ aĢ lāeĢvolution des politiques publiques. Nous preĢsenterons ensuite les traits caracteĢristiques du logement communautaire qui reĢsulte du partenariat entre la socieĢteĢ civile, les groupes de pression et lāEĢtat. Enfin, nous verrons quelques impacts de ces innovations, manifestes des changements sociaux auxquels elles contribuent. Nous conclurons avec quelques reĢflexions concernant les acquis et lāavenir de ce mouvement.Cette recherche a eĢteĢ entreprise graĢce, en partie, au soutien financier du Programme des chaires de recherche du Canada
Proteome analysis of the hyaluronic acid-producing bacterium, Streptococcus zooepidemicus
Background: Streptococcus equi subsp. zooepidemicus (S. zooepidemicus) is a commensal of horses and an opportunistic pathogen in many animals and humans. Some strains produce copious amounts of hyaluronic acid, making S. zooepidemicus an important industrial microorganism for the production of this valuable biopolymer used in the pharmaceutical and cosmetic industry. Encapsulation by hyaluronic acid is considered an important virulence factor in other streptococci, though the importance in S. zooepidemicus remains poorly understood. Proteomics may provide a better understanding of virulence factors in S. zooepidemicus, facilitate the design of better diagnostics and treatments, and guide engineering of superior production strains
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Pathologic Features of the Intervertebral Disc in Young Nova Scotia Duck Tolling Retrievers Confirms Chondrodystrophy Degenerative Phenotype Associated With Genotype.
Chondrodystrophy results in predictable and progressive biochemical and structural changes to the intervertebral disc, resulting in early onset degeneration and dystrophic mineralization of the disc. Accelerated degeneration and mineralization of the intervertebral disc are common in multiple dog breeds and can result in compromised function, herniation, pain, and a variety of neurological sequelae. A mutation responsible for chondrodystrophy in dogs has been identified as an aberrant fibroblast growth factor 4 (FGF4) retrogene insertion on chromosome 12 (CFA12) and is associated with short stature of the Nova Scotia Duck Tolling Retriever. Segregation of the CFA12 FGF4 retrogene in this dog breed provides an opportunity to examine the effect of retrogene presence on radiographic and histologic appearance of chondrodystrophic disc degeneration within a single breed. Here we found that in the intervertebral discs isolated from 2 dogs with the CFA12 FGF4 genotype, the nucleus pulposus was largely replaced by cartilaginous tissue, and physaliferous notochordal cells were rarely if ever identified. These findings are in contrast to the normal histologic findings in 2 breed-matched dogs lacking the mutation. The findings are consistent with premature chondroid degeneration of the intervertebral disc and suggest that the presence of the CFA12 FGF4 retrogene is sufficient to cause the chondrodystrophic phenotype
Lāhabitation communautaire au QueĢbec : DeĢfis et perspectives de deĢveloppement
Document de discussion pour le Symposium du 11 novembre 2009 organiseĢ par le Chantier dāactiviteĢs partenariales (CAP) Habitat de lāARUC-EĢS
Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats
<p>Abstract</p> <p>Background</p> <p>Available information suggests a mismatch between radiographic and orthopedic examination findings in cats with DJD. However, the extent of the discrepancy between clinical and radiographic signs of OA in companion animals has not been described in detail. This study aimed to evaluate the relationship between orthopedic examination findings, joint goniometry, and radiographic signs of DJD in 100 cats, in a prospective observational design. Cat temperament, pain response to palpation, joint crepitus, effusion and thickening were graded. Radiographs of appendicular joints and the axial skeleton were made under sedation. Joint motion was measured by use of a plastic goniometer before and after sedation. Associations between radiographic degenerative joint disease (DJD) and examination findings were assessed to determine sensitivity, specificity and likelihood estimations.</p> <p>Results</p> <p>Pain response to palpation was elicited in 0-67% of the joints with DJD, with a specificity ranging from 62-99%; crepitus was detected in 0-56% of the joints and its specificity varied between 87 and 99%; for effusion, values ranged between 6 and 38% (specificity, 82-100%), and thickening, 0-59% (specificity, 74-99%). Joints with DJD tended to have a decreased range of motion. The presence of pain increased the odds of having DJD in the elbow (right: 5.5; left: 4.5); the presence of pain in the lower back increased the odds of spinal DJD being present (2.97 for lumbar; 4.67 for lumbo-sacral).</p> <p>Conclusions</p> <p>Radiographic DJD cannot be diagnosed with certainty using palpation or goniometry. However, negative findings tend to predict radiographically normal joints. Palpation and goniometry may be used as a tool to help to screen cats, mostly to rule out DJD.</p
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