Sosialisasi Dan Edukasi Masyarakat Cerdas Gunakan Obat (GEMA CERMAT) Dalam Kegiatan Pengabdian Kepada Masyarakat Di Desa Deli Tua, Kabupaten Deli Serdang Sumatera Utara

Penggunaan obat bebas merupakan hal yang lumrah di masyarakat Indonesia. Untuk pengobatan penyakit dengan gejala ringan, masyarakat biasanya lebih memilih membeli obat sendiri daripada berkonsultasi dengan layanan kesehatan terlebih dahulu. Kondisi ini disebut pengobatan sendiri. Praktek pengobatan sendiri dapat memberikan keuntungan sekaligus kerugian atau risiko. Dari segi manfaat yaitu lebih hemat biaya dan waktu, sedangkan dapat merugikan jika penggunaan obat tidak tepat dan tidak tepat sasaran, hal ini dapat mengakibatkan penggunaan obat yang tidak rasional. Oleh karena itu, perlu dilakukan edukasi dan sosialisasi kepada masyarakat tentang penggunaan obat yang baik dan benar dengan menggerakkan gerakan GEMA CERMAT. Gerakan ini bertujuan untuk meningkatkan kesadaran dan pengetahuan masyarakat tentang cara memperoleh, menyimpan, menggunakan, dan membuang obat

UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER SANITIZER BUNGA LAWANG (Illiacium verum Hook. f) pada BAKTERI Staphylococcus aureus & Escherichia coli

Abstract Some diseases caused by microorganisms on the hands are diarrhea, diphteria, boils, typhus and others. The bacteria that most often contaminate the skin of the hands are Staphylococcus aureus and Escheria coli, whose spreas most often transmitted from hand to hand. Bunga lawing are one of the medicinal plants that have been used in medicine. The purpose of this study was determine the antibacterial activity of gel hand essential oil sanitizer gel preparation (Illiacium verum Hook.f) to the growth of Staphylococcus aureus and Escheria coli bacteria compared to sanitizer Dettol gel hand. This was carried out with the experimental method. Essential oil of bunga lawing is extracted using a heat method, namely soxhletation. The antibacterial activity test in this study used the agar diffusion method (disc diffusion). The measurement of the diameter of the inhibited area formed were analyzed using a one-way ANOVA statistical test. The results of antibacterial activity of bunga lawang sanitizer hand have lower antibacterial activity gel hand sanitizer Dettol. In the diameter of Staphylococcus aureus bacteria the highest rate 0f hand flower sanitizer gel was 15,1 mm while the sanitizer gel hand wash 21,4 mm. In Escheria coli bacteria, the inhibitory diameter the sanitizer hand gel dettol was obtained at 20.1 mm, while the lawang handsanitizer gel obtained the highest inhibition diameter of 13.1 mm. The results of data analysis using a one-way ANOVA statistical test showed a sig value p<0,05 so that there were significant differences between the gel hand to the inhibitory power of the growth of Staphylococcus aureus and Escheria coli bacteria.   Keywords: Bunga lawang, hand sanitizer gel, Staphylococcus aureus, Escherichia col

UJI AKTIVITAS INFLAMASI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) TERHADAP TIKUS PUTIH JANTAN (Galur wistar)

ABSTRAK Latar belakang : Inflamasi adalah suatu respon protektif terhadap cidera. Salah satu tanda inflamasi adalah edema. Kelor (Moringa oleifera L.) mengandung flavonoid sebagai zat berkhasiat utama. Flavonoid diketahui menghambat COX-2 pada proes inflamasi.Tujuan penelitian : Penelitian ini bertujuan untuk mengetahui aktivitas dan dosis efektif ekstrak sebagai anti-inflamasi. Metode : Eksperimental. Ekstrak dibuat dengan metode maserasi menggunakan pelarut tranol 80%. Uji aktivitas antiinflamasi yang dilakukan dibagi dalam 5 kelompok perlakuan. Setiap kelompok terdiri dari 3 ekor tikus putih. Kelompok pertama (kontrol negatif) diberikan 0,5% suspensi Na-CMC, kelompok ke-2 (kontrol positif) diberikan natrium diklofenak 2,25 mg/kgBB, sedangkan kelompok ke-3, ke-4 dan ke-5 secara berturut-turut diberikan ekstrak etanol daun kelor sebesar 100, 150, dan 200 mg/kgBB. Masingmasing tikus kemudian diinduksi menggunakan karagenan 1% secara subplantar. Volume radang diukur menggunakan plestimometer dilakukan selama 3 jam dengan interval waktu 30 menit. Data dianalisis secara statistik menggunakan ANOVA (analysis of Variance). Hasil : Hasil penelitian menunjukkan bahwa kontrol negatif memiliki perbedaan yang signifikan dengan kelompok perlakuan lainnya dimana tidak menunjukkan efek anti-inflamasi. Kesimpulan : Ekstrak etanol daun kelor 200 mg/kgBB memiliki efek antiinflamasi yang paling baik dibandingkan dengan ekstrak etanol 100, 150 mg/kgBB, tetapi masih berada dibawah Na-Diklofenak. Kata Kunci : Ekstrak etanol, Moringa oleifera L., Anti-inflamasi, Volume rada

SOSIALISASI MENJAGA KEBERSIHAN DIRI (PERSONAL HYGIENE) PADA PANTI ASUHAN ANAK LIORA TERANG

For kids, maintaining personal hygiene is crucial because they often get sick due to not paying attention to it. Personal hygiene is the practice of preserving the health and sanitation of children for their physical and mental well-being. Personal hygiene knowledge must be acquired at an early age. The aim is that the child's knowledge about personal hygiene will become more mature, so that the child will get used to practicing personal hygiene. Apart from that, to increase knowledge about maintaining cleanliness in everyday life. In the process of internalizing personal hygiene behavior, there are several behaviors such as washing hands, bathing, shampooing (washing hair), brushing teeth, cutting nails, and cleaning ears. Presentations were utilized to conduct this activity, group discussions with orphanage children, and continued by providing education about the value of good personal hygiene and methods for practicing it in everyday life. This activity took place with a total of 21 participants. The personal hygiene material presented, includes: the benefits of maintaining personal hygiene, how to practice proper personal hygiene, including hand cleansing, tooth flossing, bathing, shampooing, cutting nails, changing clothes and not sharing personal items with other people. Apart from that, environmental hygiene material was also presented including: keeping the house clean, such as cleaning the floor of the house, not piling up dirty clothes and always changing bed linen regularly

UJI EFEK EKSTRAK ETANOL DAUN SALAM (Syzygiumpolyanthum) SEBAGAI DIURETIKA PADA TIKUS PUTIH JANTAN

Bay leaf is a plant that one of its benefits is as a diuretic. Diuretics are drugs that act directly on the kidneys and increase the excretion of urine and sodium salts. The aim of the study was to determine the diuretic effect of ethanol extract of bay leaf (EEDS) on male white rats. The study used 25 male white rats, divided into 5 treatment groups: negative control group (CMC suspension 0.5%), positive control (furosemide suspension at a dose of 3.6 mg/kg BW), and a test group EEDS suspension at a dose of 100 mg/kg. BW, 200 mg/kg BW and 300 mg/kg BW. The test preparation was given orally to rats and then observed in a modified metabolic cage for 6 hours. The results of simplicia phytochemical screening showed positive for flavonoids, saponins and tannins. The results of EEDS characterization included a total ash content of 3.66%, water-soluble extract content of 3.69%, and ethanol-soluble extract content of 3.65%. The results showed that EEDS at a dose of 300 mg/kg BW showed the best diuretic effect compared to 200 mg/kg BW and 100 mg/kg BW, but the effect was lower than S. Furosemide 3.6 mg/kg BW. The results of the ANOVA EEDS test at doses of 100, 200 and 300 mg/kg BW had significant differences

U UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL HAND SANITIZER SANITIZER BUNGA LAWANG (Illiacium verum Hook. f) pada BAKTERI Staphylococcus aureus & Escherichia coli

Some diseases caused by microorganisms on the hands are diarrhea, diphteria, boils, typhus and others. The bacteria that most often contaminate the skin of the hands are Staphylococcus aureus and Escheria coli, whose spreas most often transmitted from hand to hand. Bunga lawing are one of the medicinal plants that have been used in medicine. The purpose of this study was determine the antibacterial activity of gel hand essential oil sanitizer gel preparation (Illiacium verum Hook.f) to the growth of Staphylococcus aureus and Escheria coli bacteria compared to sanitizer Dettol gel hand. This was carried out with the experimental method. Essential oil of bunga lawing is extracted using a heat method, namely soxhletation. The antibacterial activity test in this study used the agar diffusion method (disc diffusion). The measurement of the diameter of the inhibited area formed were analyzed using a one-way ANOVA statistical test. The results of antibacterial activity of bunga lawang sanitizer hand have lower antibacterial activity gel hand sanitizer Dettol. In the diameter of Staphylococcus aureus bacteria the highest rate 0f hand flower sanitizer gel was 15,1 mm while the sanitizer gel hand wash 21,4 mm. In Escheria coli bacteria, the inhibitory diameter the sanitizer hand gel dettol was obtained at 20.1 mm, while the lawang hand sanitizer gel obtained the highest inhibition diameter of 13.1 mm. The results of data analysis using a one-way ANOVA statistical test showed a sig value p<0,05 so that there were significant differences between the gel hand to the inhibitory power of the growth of Staphylococcus aureus and Escheria coli bacteria

Effects EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) SEED POWDER ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN-INDUCED MICE

Objective: The aim of this research is to evaluate the antidiabetic effect of pumpkin seed powder in streptozotocin (STZ)-induced diabetic mice. Methods: Pumpkin seed was used in seed powder suspension form and then evaluate the phytochemical screening and induced diabetic mice using STZ. Results: The phytochemical screening showed that pumpkin seed powder has various of phytochemical compounds. The pumpkin seed powder (dose level 100, 150, and 200 mg/kg bw) showed a significant reduction of blood glucose. Conclusions: Pumpkin seed powder significantly decreases blood glucose level in STZ-induced mice

ANTIDIABETIC EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) FLESH AND SEEDS EXTRACTS IN STREPTOZOTOCIN INDUCED MICE

 Objective: The present study is to investigate the antidiabetic effect of pumpkin flesh and seeds ethanolic extracts in STZ-induced diabetic mice.Methods: The study begins with making the ethanolic extracts of pumpkin flesh and seeds and then evaluates the physicochemical characterization, phytochemical screening, and induced diabetic mice using STZ.Result: The physicochemical evaluation shows that the extracts had a good and high purity level, while the phytochemical screening showed both pumpkin flesh and seeds extracts have a various of phytoconstituents. The pumpkin flesh and seeds ethanolic extracts (dose level 150 mg/kg) showed a significant reduction of the blood glucose.Conclusion: Pumpkin flesh and seeds ethanolic extracts exhibited significant antidiabetes activity in STZ-induced mice

ANTIDIABETIC EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) FLESH AND SEEDS EXTRACTS IN STREPTOZOTOCIN INDUCED MICE

 Objective: The present study is to investigate the antidiabetic effect of pumpkin flesh and seeds ethanolic extracts in STZ-induced diabetic mice.Methods: The study begins with making the ethanolic extracts of pumpkin flesh and seeds and then evaluates the physicochemical characterization, phytochemical screening, and induced diabetic mice using STZ.Result: The physicochemical evaluation shows that the extracts had a good and high purity level, while the phytochemical screening showed both pumpkin flesh and seeds extracts have a various of phytoconstituents. The pumpkin flesh and seeds ethanolic extracts (dose level 150 mg/kg) showed a significant reduction of the blood glucose.Conclusion: Pumpkin flesh and seeds ethanolic extracts exhibited significant antidiabetes activity in STZ-induced mice