Tos Ferina en una lactante no inmunizada: a propósito de un caso

ResumenIntroducciónLas afecciones respiratorias son un problema de salud común entre los lactantes.Reporte de casoUna lactante de 75 días de edad fue llevada a urgencias por disnea y tos paroxística espasmódica, emetizante y cianosante. No estaba inmunizada contra tos ferina y tuvo contacto con su gemela, que tenía una infección por probable Bordetella pertussis. El diagnóstico de egreso fue bronquiolitis. Días después, reingresó por disnea.DiscusiónEn los lactantes, la tos ferina, el síndrome coqueluchoide y la bronquiolitis tienen manifestaciones clínicas comunes. Este caso resalta la importancia de seguir las guías de práctica clínica y los procedimientos de diagnóstico de B. pertussis, así como el análisis epidemiológico de los casos probables, debido a que de ello depende el tratamiento etiológico y, por lo tanto, el pronóstico de los pacientes.AbstractIntroductionRespiratory tract infections are a common cause of infant morbidity, and even mortality.Case reportA two-month old female was taken to the Emergency Department after she suddenly developed dyspnoea and a paroxysmal, spasmodic, cyanosing cough. Her vaccination scheme was incomplete and she had contact with her twin sister, who had an infection probably caused by Bordetella pertussis. The discharge diagnosis was bronchiolitis. She was re-admitted to hospital a few days later with an exacerbation of her dyspnoea.DiscussionThis case highlights the importance of following the clinical practice guidelines and the standard procedures for the diagnosis of B. pertussis, while the epidemiological context of patients should always be considered. It is important to correctly identify the aetiological agent, as the specific treatment is based on the aetiology, and both of them determine the prognosis of the patients

Trends in adult asthma hospitalization: gender-age effect

BACKGROUND: Hospital admissions due to asthma are a reliable source of information on the morbidity of the disease which, after the increase observed in the last quarter of the last century, shows a declining trend in the last few years. The aim of this study was to look at hospital admission trends due to asthma in our community and analyze some of its associated factors. METHODS: Retrospective analysis of all hospital admissions involving adults aged 15 years and older with asthma as the primary or secondary diagnosis (if the first diagnosis was respiratory failure or respiratory infection) in Public Health Service hospitals in the Galician region of Spain between the years 1995-2009 (total 24,766 admissions). RESULTS: The majority of patients admitted were female (71%), over 60 years of age (64%), and admission occurred predominantly in the winter months. The hospitalization rate due to asthma tripled over the period studied, this being mainly accounted for by women aged over 60 years. Mean hospital stay was 9.2 days, longer in older patients or those admitted over the weekend. CONCLUSIONS: A significant increase in hospital admissions due to asthma over the last few years has been observed in our community, mainly involving older women. The mean stay seems long, increasing with patients' age and admission over the weekend

Measurement of inelastic J / psi photoproduction at HERA

We present a measurement of the inelastic, non diffractive J/$\psi$ photoproduction cross section in the reaction $e^{+} p \to e^{+} {J}/\psi X$ with the ZEUS detector at HERA. The J/$\psi$ was identified using both the $\mu^{+}\mu^{-}$ and $e^{+}e^{-}$ decay channels and events were selected within the range $0.4<z<0.9$ ($0.5<z<0.9$) for the muon (electron) decay mode, where $z$ is the fraction of the photon energy carried by the J/$\psi$ in the proton rest frame. The cross section, the $p^2_T$ and the $z$ distributions, after having subtracted the contributions from resolved photon and diffractive proton dissociative processes, are given for the photon-proton centre of mass energy range $50<W<180$ GeV; $p^2_T$ is the square of the J/$\psi$ transverse momentum with respect to the incoming proton beam direction. In the kinematic range $0.4 1$ GeV$^2$, NLO calculations of the photon-gluon fusion process based on the colour-singlet model are in good agreement with the data. The predictions of a specific leading order colour-octet model, as formulated to describe the CDF data on J/$\psi$ hadroproduction, are not consistent with the data.Comment: 31 pages including 7 figure