Same Sign WW Scattering Process as a Probe of Higgs Boson in pp Collision at s\sqrt{s} = 10 TeV

WW scattering is an important process to study electroweak symmetry breaking in the Standard Model at the LHC, in which the Higgs mechanism or other new physics processes must intervene to preserve the unitarity of the process below 1 TeV. This channel is expected to be one of the most sensitive to determine whether the Higgs boson exists. In this paper, the final state with two same sign Ws is studied, with a simulated sample corresponding to the integrated luminosity of 60 fb$^{-1}$ in pp collision at $\sqrt{s}=$10 TeV. Two observables, the invariant mass of $\mu\mu$ from W decays and the azimuthal angle difference between the two $\mu$s, are utilized to distinguish the Higgs boson existence scenario from the Higgs boson absence scenario. A good signal significance for the two cases can be achieved. If we define the separation power of the analysis as the distance, in the log-likelihood plane, of pseudo-experiments outcomes in the two cases, with the total statistics expected from the ATLAS and CMS experiments at the nominal centre-of-mass energy of 14 TeV, the separation power will be at the level of 4 $\sigma$.Comment: 5 pages, 4 figures, 3 table

KidneyRegNet: A Deep Learning Method for 3DCT-2DUS Kidney Registration during Breathing

This work proposed a novel deep registration pipeline for 3D CT and 2D U/S kidney scans of free breathing, which consists of a feature network, and a 3D-2D CNN-based registration network. The feature network has handcraft texture feature layers to reduce the semantic gap. The registration network is encoder-decoder structure with loss of feature-image-motion (FIM), which enables hierarchical regression at decoder layers and avoids multiple network concatenation. It was first pretrained with retrospective datasets cum training data generation strategy, then adapted to specific patient data under unsupervised one-cycle transfer learning in onsite application. The experiment was on 132 U/S sequences, 39 multiple phase CT and 210 public single phase CT images, and 25 pairs of CT and U/S sequences. It resulted in mean contour distance (MCD) of 0.94 mm between kidneys on CT and U/S images and MCD of 1.15 mm on CT and reference CT images. For datasets with small transformations, it resulted in MCD of 0.82 and 1.02 mm respectively. For large transformations, it resulted in MCD of 1.10 and 1.28 mm respectively. This work addressed difficulties in 3DCT-2DUS kidney registration during free breathing via novel network structures and training strategy.Comment: 15 pages, 8 figures, 9 table

Geology and Geochronology of the Miocene Rio Blanco Porphyry Cu-Mo Deposit, Northern Peru

The Rio Blanco porphyry Cu-Mo deposit occurs at the north end of the Miocene metallogenic belt of northern Peru. It has a thick supergene enrichment blanket; while normal for hyperarid Chile, this is unusual in mountainous, cloud forest terrain. Rio Blanco is hosted by the Portachuela batholith. Zircon U-Pb dating shows that the youngest part of the batholith was emplaced at 12.43 ± 0.13 Ma. The deposit formed during three magmatic-hydrothermal cycles. Cycle 1, by far the most important, occurred at 11.50 ± 0.17 to 10.92 ± 0.14 Ma (zircon U-Pb). Two intermineralization intrusions caused early potassic and propylitic alteration. This was then overprinted by a blanket of quartz-sericite, grading down into sericite-chlorite alteration. Cycle 1 was finally cut by a quartz-sericite–cemented breccia, which contains the highest-grade hypogene Cu-Mo grades. A cycle 1 molybdenite-bearing vein has a molybdenite Re-Os model age of 11.43 ± 0.16 Ma. Molybdenite Re-Os dating of the quartz-sericite–cemented breccias shows brecciation occurred at 11.28 ± 0.24 to 11.11 ± 0.18 Ma. Cycle 2 was restricted to the east side, where narrow porphyritic dacite 1 dikes (dated by zircon U-Pb at 10.62 ± 0.16 Ma) show biotite alteration and economic copper. Cycle 3, at 10.02 ± 0.12 to 9.06 ± 0.09 Ma (zircon U-Pb), was triggered by a swarm of NE-striking quartz-plagioclase porphyry and porphyritic dacite 2 dikes. Alteration was milder, and this cycle did not introduce economic copper. Nonmineralized pebble dikes cut the system, emanating from a major diatreme, about 3 × 1.3 km in size, on the north side of the deposit. The magmatic-hydrothermal history spanned about 2.5 m.y., with economic mineralization over about 1.48 m.y. However, metals were mostly introduced during cycle 1, which lasted approximately 0.58 m.y. Our work shows that while multiple magmatic-hydrothermal cycles produced Rio Blanco, sufficient metals were introduced to form a giant porphyry deposit within a single magmatic-hydrothermal cycle

Experimental investigation about the influence of airflow on droplet sizes of mechanical nozzles for coal mining face

Visokotlačno raspršivanje je jedna od primarnih metoda za sprječavanje prašine u potpuno mehaniziranom iskopu, a učinci raspršivanja mehaničkih mlaznica značajno utječu na učinak raspršivanja. Do sada su mlaznice uglavnom odabirane subjektivnom proizvoljnošću tehničara, utječući na poboljšanje učinka suzbijanja prašine. Iz tog razloga, prije i poslije simulacije stvarne brzine zraka iskopa ugljena, provedeni su usporedni pokusi učinaka atomizacije na šest vrsta najčešće korištenih mehaničkih mlaznica s vlastitom platformom za prskanje. Na osnovu podataka o ispitivanju dobivene su prosječne veličine kapljica i redoslijed kvalitete raspršivanja različitih mehaničkih mlaznica, a osim toga je induciran utjecaj turbulencije protoka zraka na veličine kapljica. Konačno, prema eksperimentalnim rezultatima, mlaznice koje se koriste u vanjskom raspršivaču su odabrane za #10310 radnih iskopa rudnika ugljena Xinglongzhuang u Kini, koji je postigao velike učinke smanjenja prašine.High-pressure spraying is one of the primary methods for dust prevention in coal mine fully mechanized caving face, and the atomization effects of mechanical nozzles influence dedusting result significantly. While so far, the nozzles are selected by technician’s subjective arbitrariness mainly, affecting improving dedusting effect. For this reason, before and after simulating actual air velocity of coal workface, the comparative experiments on the atomization effects of the six kinds of commonly used mechanical nozzles were conducted with self-designed spraying platform. Based on the test data, the average droplets’ size and the atomization quality order of different mechanical nozzles were obtained, moreover, the airflow’s turbulence influence on droplets’ sizes was induced. Finally, according to the experimental results, nozzles used in external spray of shearer were selected for #10310 working face of Xinglongzhuang coal mine in China, which had achieved great dust reduction effects

Intelligence Deficits in Chinese Patients with Brain Tumor: The Impact of Tumor Resection

Background. Intelligence is much important for brain tumor patients after their operation, while the reports about surgical related intelligence deficits are not frequent. It is not only theoretically important but also meaningful for clinical practice. Methods. Wechsler Adult Intelligence Scale was employed to evaluate the intelligence of 103 patients with intracranial tumor and to compare the intelligence quotient (IQ), verbal IQ (VIQ), and performance IQ (PIQ) between the intracerebral and extracerebral subgroups. Results. Although preoperative intelligence deficits appeared in all subgroups, IQ, VIQ, and PIQ were not found to have any significant difference between the intracerebral and extracerebral subgroups, but with VIQ lower than PIQ in all the subgroups. An immediate postoperative follow-up demonstrated a decline of IQ and PIQ in the extracerebral subgroup, but an improvement of VIQ in the right intracerebral subgroup. Pituitary adenoma resection exerted no effect on intelligence. In addition, age, years of education, and tumor size were found to play important roles. Conclusions. Brain tumors will impair IQ, VIQ, and PIQ. The extracerebral tumor resection can deteriorate IQ and PIQ. However, right intracerebral tumor resection is beneficial to VIQ, and transsphenoidal pituitary adenoma resection performs no effect on intelligence

O-GlcNAcylation of G6PD Promotes the Pentose Phosphate Pathway and Tumor Growth

The pentose phosphate pathway (PPP) plays a critical role in macromolecule biosynthesis and maintaining cellular redox homoeostasis in rapidly proliferating cells. Upregulation of the PPP has been shown in several types of cancer. However, how the PPP is regulated to confer a selective growth advantage on cancer cells is not well understood. Here we show that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the PPP, is dynamically modified with an O-linked b-N-acetylglucosamine sugar in response to hypoxia. Glycosylation activates G6PD activity and increases glucose flux through the PPP, thereby providing precursors for nucleotide and lipid biosynthesis, and reducing equivalents for antioxidant defense. Blocking glycosylation of G6PD reduces cancer cell proliferation in vitro and impairs tumor growth in vivo. Importantly, G6PD glycosylation is increased in human lung cancers. Our findings reveal a mechanistic understanding of how O-glycosylation directly regulates the PPP to confer a selective growth advantage to tumours

Design and Research of Electron Cyclotron Resonance Heating and Current Dive System on HL-2M Tokamak

A research has been conducted to develop an 8MW electron cyclotron resonance heating and current drive (ECRH/ECCD) system on HL-2M tokamak. The ECRH system compromise eight 1MW gyrotrons, eight evacuated transmission lines and three launchers. The main purpose of the ECRH system was to suppress the neo-classical tearing modes and control the plasma profile. This paper presents an overview of the design and studies performed in this framework. Some primary test results of the critical components have been released in this paper, e.g. polarizers, power monitor and fast steering launchers