278 research outputs found
Finding Home Catalogue
Our stories are lifelines, traveling with us, tossed between continents, hidden, preserved, pulled out when needed. They are narratives told at refugee hearings, poems written long past midnight, films emerging from long pandemic days, phrases wrought from the scars of exile, the joys of freedom. This catalogue documents our research project Finding Home and the outcomes
3D Position Sensitive XeTPC for Dark Matter Search
The technique to realize 3D position sensitivity in a two-phase xenon time
projection chamber (XeTPC) for dark matter search is described. Results from a
prototype detector (XENON3) are presented.Comment: Presented at the 7th UCLA Symposium on "Sources and Detection of Dark
Matter and Dark Energy in the Universe
Constraints on inelastic dark matter from XENON10
It has been suggested that dark matter particles which scatter inelastically
from detector target nuclei could explain the apparent incompatibility of the
DAMA modulation signal (interpreted as evidence for particle dark matter) with
the null results from CDMS-II and XENON10. Among the predictions of
inelastically interacting dark matter are a suppression of low-energy events,
and a population of nuclear recoil events at higher nuclear recoil equivalent
energies. This is in stark contrast to the well-known expectation of a falling
exponential spectrum for the case of elastic interactions. We present a new
analysis of XENON10 dark matter search data extending to E keV
nuclear recoil equivalent energy. Our results exclude a significant region of
previously allowed parameter space in the model of inelastically interacting
dark matter. In particular, it is found that dark matter particle masses
GeV are disfavored.Comment: 8 pages, 4 figure
Cardiorespiratory Progression Over 5 Years and Role of Corticosteroids in Duchenne Muscular Dystrophy: A Single-Site Retrospective Longitudinal Study
Background:
Duchenne muscular dystrophy (DMD) boys treated with corticosteroids (CS) have prolonged survival and respiratory function when compared to CS-naïve. /\ud
Research question:
The differential impact of frequently used corticosteroids and their regimens on long-term (>5 years) cardiorespiratory progression in DMD children is unknown. /
Study Design and Methods: Retrospective longitudinal study including DMD children followed at Dubowitz Neuromuscular Centre (Great Ormond Street Hospital London), May 2000-June 2017. Patients enrolled in any interventional clinical trials were excluded. We collected patients’ anthropometrics, respiratory (forced vital capacity, FVC% predicted and absolute FVC, non-invasive ventilation requirement, NIV) and cardiac (left ventricular shortening function, LVFS%) function. CS-naïve patients had never received CS. CS-treated took either deflazacort or prednisolone, daily or intermittently (10 days on/10 days off) for >1 month. Average longitudinal models were fitted for yearly respiratory (FVC%P) and cardiac (LVFS%) progression. A time-to-event analysis to FVC%P<50%, NIV start and cardiomyopathy (LVFS<28%) was performed in CS-treated (daily and intermittent) vs CS-naïve patients. /
Results:
There were 270 patients, mean age at baseline 6.2 (±2.3) years. Median follow-up 5.6 (± 3.5) years. At baseline, 263 were ambulant. Sixty-six were CS-daily, 182 CS-intermittent >60% treatment, 22 CS-naïve. Yearly FVC%P declined similarly from 9 years (5.9% and 6.9%/year, p=0.27) in CS-daily and CS-intermittent. CS-daily declined from a higher FVC%P than CS-intermittent (p2 years later than CS-treated. LVFS% declined by 0.53%/year in CS-treated irrespective of CS regimen, significantly slower (p<0.01) than CS-naïve progressing by 1.17%/year. Age at cardiomyopathy was 16.6 in CS-treated (p<0.05) irrespective of regimen and 13.9 years in CS-naïve. /
Interpretation:
CS irrespective of their regimen significantly improved respiratory function and delayed NIV requirement and cardiomyopathy
A search for light dark matter in XENON10 data
We report results of a search for light (<10 GeV) particle dark matter with
the XENON10 detector. The event trigger was sensitive to a single electron,
with the analysis threshold of 5 electrons corresponding to 1.4 keV nuclear
recoil energy. Considering spin-independent dark matter-nucleon scattering, we
exclude cross sections \sigma_n>3.5x10^{-42} cm^2, for a dark matter particle
mass m_{\chi}=8 GeV. We find that our data strongly constrain recent elastic
dark matter interpretations of excess low-energy events observed by CoGeNT and
CRESST-II, as well as the DAMA annual modulation signal.Comment: Manuscript identical to v2 (published version) but also contains
erratum. Note v3==v2 but without \linenumber
First Results from the XENON10 Dark Matter Experiment at the Gran Sasso National Laboratory
The XENON10 experiment at the Gran Sasso National Laboratory uses a 15 kg
xenon dual phase time projection chamber (XeTPC) to search for dark matter
weakly interacting massive particles (WIMPs). The detector measures
simultaneously the scintillation and the ionization produced by radiation in
pure liquid xenon, to discriminate signal from background down to 4.5 keV
nuclear recoil energy. A blind analysis of 58.6 live days of data, acquired
between October 6, 2006 and February 14, 2007, and using a fiducial mass of 5.4
kg, excludes previously unexplored parameter space, setting a new 90% C.L.
upper limit for the WIMP-nucleon spin-independent cross-section of 8.8 x
10^{-44} cm^2 for a WIMP mass of 100 GeV/c^2, and 4.5 x 10^{-44} cm^2 for a
WIMP mass of 30 GeV/c^2. This result further constrains predictions of
supersymmetric models.Comment: accepted for publication in Phys. Rev. Let
Dark Matter Direct Detection with Non-Maxwellian Velocity Structure
The velocity distribution function of dark matter particles is expected to
show significant departures from a Maxwell-Boltzmann distribution. This can
have profound effects on the predicted dark matter - nucleon scattering rates
in direct detection experiments, especially for dark matter models in which the
scattering is sensitive to the high velocity tail of the distribution, such as
inelastic dark matter (iDM) or light (few GeV) dark matter (LDM), and for
experiments that require high energy recoil events, such as many directionally
sensitive experiments. Here we determine the velocity distribution functions
from two of the highest resolution numerical simulations of Galactic dark
matter structure (Via Lactea II and GHALO), and study the effects for these
scenarios. For directional detection, we find that the observed departures from
Maxwell-Boltzmann increase the contrast of the signal and change the typical
direction of incoming DM particles. For iDM, the expected signals at direct
detection experiments are changed dramatically: the annual modulation can be
enhanced by more than a factor two, and the relative rates of DAMA compared to
CDMS can change by an order of magnitude, while those compared to CRESST can
change by a factor of two. The spectrum of the signal can also change
dramatically, with many features arising due to substructure. For LDM the
spectral effects are smaller, but changes do arise that improve the
compatibility with existing experiments. We find that the phase of the
modulation can depend upon energy, which would help discriminate against
background should it be found.Comment: 34 pages, 16 figures, submitted to JCAP. Tables of g(v_min), the
integral of f(v)/v from v_min to infinity, derived from our simulations, are
available for download at http://astro.berkeley.edu/~mqk/dmdd
Single electron emission in two-phase xenon with application to the detection of coherent neutrino-nucleus scattering
We present an experimental study of single electron emission in ZEPLIN-III, a
two-phase xenon experiment built to search for dark matter WIMPs, and discuss
applications enabled by the excellent signal-to-noise ratio achieved in
detecting this signature. Firstly, we demonstrate a practical method for
precise measurement of the free electron lifetime in liquid xenon during normal
operation of these detectors. Then, using a realistic detector response model
and backgrounds, we assess the feasibility of deploying such an instrument for
measuring coherent neutrino-nucleus elastic scattering using the ionisation
channel in the few-electron regime. We conclude that it should be possible to
measure this elusive neutrino signature above an ionisation threshold of
3 electrons both at a stopped pion source and at a nuclear reactor.
Detectable signal rates are larger in the reactor case, but the triggered
measurement and harder recoil energy spectrum afforded by the accelerator
source enable lower overall background and fiducialisation of the active
volume
The scintillation and ionization yield of liquid xenon for nuclear recoils
XENON10 is an experiment designed to directly detect particle dark matter. It
is a dual phase (liquid/gas) xenon time-projection chamber with 3D position
imaging. Particle interactions generate a primary scintillation signal (S1) and
ionization signal (S2), which are both functions of the deposited recoil energy
and the incident particle type. We present a new precision measurement of the
relative scintillation yield \leff and the absolute ionization yield Q_y, for
nuclear recoils in xenon. A dark matter particle is expected to deposit energy
by scattering from a xenon nucleus. Knowledge of \leff is therefore crucial for
establishing the energy threshold of the experiment; this in turn determines
the sensitivity to particle dark matter. Our \leff measurement is in agreement
with recent theoretical predictions above 15 keV nuclear recoil energy, and the
energy threshold of the measurement is 4 keV. A knowledge of the ionization
yield \Qy is necessary to establish the trigger threshold of the experiment.
The ionization yield \Qy is measured in two ways, both in agreement with
previous measurements and with a factor of 10 lower energy threshold.Comment: 8 pages, 9 figures. To be published in Nucl. Instrum. Methods
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