Percutaneous nephrostomy or double J stenting, which is better modality for obstructive uropathy-a descriptive study

Background: Percutaneous Nephrostomy or Ureteric Stenting is indicated in patients with Acute Renal Failure following urinary tract obstruction. The purpose of this study was to evaluate the better treatment modality in terms of S. Creatinine level.  Methods: Total 50 patients with Creatinine level of >2 mg/dl and hydronephrosis due to upper urinary tract obstruction were grouped into either percutaneous nephrostomy or stent insertion groups. These patients were then evaluated by overall trend of S. creatinine and urine output levels postoperatively.Results: Two comparable groups of PCN and DJS were formed with a mean age of 45.5 years and 47.9 years. Male to female ratio was 1.5:1 and 1.2:1 respectively. Pain with oliguria or anuria was the major presentation. The urine output levels showed a sudden increase postoperatively with a subsequent trend towards normal value in both the groups. Creatinine however showed a normalizing trend from a mean 6.46 mg/dl preoperatively to 1.01mg/dl postoperatively in PCN group whereas in DJS group 5.38mg/dl preoperatively to 2.75mg/dl with a rising trend from POD 15 requiring conversion to PCN in 20% of patients with subsequent normalization of creatinine levels to 0.95 mg/dl. Statistically we found no difference in the outcome when both the groups were compared in view of serum creatinine and urine output levels whereas there is a significant difference in the pre and post operative outcome of both the groups.  Conclusions: Our results thus support that though there is no significant difference among both the procedures, ureteral stents are associated with intolerable lower urinary tract symptoms owing to conversion to secondary percutaneous Nephrostomy. Hence percutaneous nephrostomy is superior to ureteral stents for diversion of urine in patients with ARF due to obstructive uropathy.

A New Drop Fluidics Enabled by Magnetic Field Mediated Elasto-Capillary Transduction

This research introduces a new drop fluidics, which uses a deformable and stretchable elastomeric film as the platform, instead of the commonly used rigid supports. Such a soft film impregnated with magnetic particles can be modulated with an external electromagnetic field that produces a vast array of topographical landscapes with varying surface curvature, which, in conjunction with capillarity, can direct and control motion of water droplets efficiently and accurately. When a thin layer of oil is present on this film that is deformed locally, a centrosymmetric wedge is formed. A water droplet placed on this oil laden film becomes asymmetrically deformed thus producing a gradient of Laplace pressure within the droplet setting it to motion. A simple theory is presented that accounts for the droplet speed in terms of such geometric variables as the volume of the droplet and the thickness of the oil film covering the soft elastomeric film, as well as such material variables as the viscosity of the oil and interfacial tension of the oil-water interfaces. Following the verification of the theoretical result using well-controlled model systems, we demonstrate how the electromagnetically controlled elasto-capillary force can be used to manipulate the motion of single and/or multiple droplets on the surface of the elastomeric film and how such elementary operations as drop fusion and thermally addressed chemical transformation can be carried out in aqueous droplets. It is expected that the resulting drop fluidics would be suitable for digital control of drop motion by simply switching on and off the electromagnetic fields applied at different positions underneath the elastomeric film. We anticipate that this method of directing and manipulating water droplets is poised for its applications in various biochemical reaction engineering, an example of which is Polymerase Chain Reaction (PCR)

Pred&Guide: Labeled Target Class Prediction for Guiding Semi-Supervised Domain Adaptation

Semi-supervised domain adaptation aims to classify data belonging to a target domain by utilizing a related label-rich source domain and very few labeled examples of the target domain. Here, we propose a novel framework, Pred&Guide, which leverages the inconsistency between the predicted and the actual class labels of the few labeled target examples to effectively guide the domain adaptation in a semi-supervised setting. Pred&Guide consists of three stages, as follows (1) First, in order to treat all the target samples equally, we perform unsupervised domain adaptation coupled with self-training; (2) Second is the label prediction stage, where the current model is used to predict the labels of the few labeled target examples, and (3) Finally, the correctness of the label predictions are used to effectively weigh source examples class-wise to better guide the domain adaptation process. Extensive experiments show that the proposed Pred&Guide framework achieves state-of-the-art results for two large-scale benchmark datasets, namely Office-Home and DomainNet

Opinion dynamics model with domain size dependent dynamics: novel features and new universality class

A model for opinion dynamics (Model I) has been recently introduced in which the binary opinions of the individuals are determined according to the size of their neighboring domains (population having the same opinion). The coarsening dynamics of the equivalent Ising model shows power law behavior and has been found to belong to a new universality class with the dynamic exponent $z=1.0 \pm 0.01$ and persistence exponent $\theta \simeq 0.235$ in one dimension. The critical behavior has been found to be robust for a large variety of annealed disorder that has been studied. Further, by mapping Model I to a system of random walkers in one dimension with a tendency to walk towards their nearest neighbour with probability $\epsilon$, we find that for any $\epsilon > 0.5$, the Model I dynamical behaviour is prevalent at long times.Comment: 12 pages, 10 figures. To be published in "Journal of Physics : Conference Series" (2011

Mechanistic-empirical Design of Perpetual Road Pavement Using Strain-based Design Approach

Present paper deals with the development of a Mechanistic-Empirical model of the strain-based design of perpetual road pavement using Odemark's principle. The bituminous pavement which can withstand minimum design traffic of 300 msa has been classified as perpetual pavement in this paper. The pavement has been considered as a three-layered system with a top layer of bituminous mix followed by unbound granular materials which rest on soil subgrade. The constituent bituminous layer thickness in the pavement has been determined by limiting the radial tensile strain at the bottom of the bituminous layer against fatigue and the vertical compressive strain at the top of the subgrade against rutting. The allowable strain against rutting and fatigue has been used in the present analysis from mechanistic-empirical correlations recommended in IRC:37-2018. The pavement section has been transformed into a homogeneous system by Odemark's method for application of Boussinesq's theory. To validate the thickness of the perpetual pavement, the strain at different layer interfaces in the pavement was compared using IITPAVE software, which shows the pavement section using present method is safe against rutting but marginally fails under fatigue. Moreover, conventional pavement thickness obtained using IRC:37-2018 were compared with the present method, which shows reasonably good convergence. It has been found that the bituminous layer thickness in a layered system of pavement seems to be more sensitive to fatigue than rutting. In this backdrop, modified fatigue and rutting strain values have been recommended for the design of perpetual road pavement

The 2010 Outbreak of Cholera among Workers of a Jute Mill in Kolkata, West Bengal, India

On 10 March 2010, an outbreak of diarrhoeal disease was reported among workers of a jute mill in Kolkata, West Bengal, India. The cluster was investigated to identify the agent(s) and the source of infection and make recommendations. A suspected case of cholera was defined as having >3 loose watery stools in a 24-hour period and searched for case-patients in the workers’ colony. The outbreak was described by time, place, and person, and a case-control study was conducted to identify the source of infection. Rectal swabs were collected from the hospitalized case-patients, and the local water-supply system was assessed. In total, 197 case-patients were identified among 5,910 residents of the workers’ colony (attack rate 3.33%). Fifteen of 24 stool samples were positive for Vibrio cholerae O1. The outbreak started on 7 March, peakedon 11 March, and ended on 16 March 2010. Compared to 120 controls, 60 cases did not differ in terms of age and socioeconomic status. Drinking-water from the reservoir within the mill premises was associated with an increased risk of illness [odds ratio: 26.7, 95% confidence interval (CI) 11.4-62.6) and accounted for most cases (population attributable risk percentage=82%, 95% CI 70.8-92.9). An outbreak of cholera occurred among workers of the jute mill due to contamination of the drinking-water reservoir. It occurred within a few days of re-opening of the mill after the workers’ strike. Health authorities need to enforce disinfection of drinking-water and regularly test its bacteriological quality, particularly before re-opening of the mill after the strike

Isolated hydatid cyst of adrenal gland with hypertension mimicking Conn’s syndrome: a very rare case

Hydatid cyst of the adrenal gland is one of the rare conditions caused by the larval stage of Echinococcus granulosus. The incidence of adrenal gland involvement is less than 1% of all hydatid disease in humans and isolated adrenal involvement is extremely rare. Hydatid disease is frequent in endemic regions and sheep farming areas with equal sex distribution. Here, a case of 23 year old female with isolated adrenal gland hydatid cyst is presented, that was evaluated clinically, investigated radiographicaly and by blood investigations and finally histopathology confirmed the diagnosis. No complications occurred at peri and postoperative period. The patient was given 6 cycles of albendazole (10 mg/kg in two divided doses), each for a period of four weeks followed by a week’s rest. The patient is on regular follow-up without recurrence in last 1 year

Percutaneous nephrolithotripsy for renal pelvis stone in a crossed fused ectopic kidney: a case report

Crossed renal ectopia is the second most common fusion anomaly of the kidney after horseshoe kidney. The incidence of both fused and unfused cases is 1 in 7000 in autopsies. Percutaneous nephrolithotripsy (PCNL) is a well-established technique in the surgical management of nephrolithiasis. The conventional fluoroscopic guidance of PCNL will be of limited value in ectopic anomalous kidneys due to the abnormal anatomical landmarks with consequent compromise of the procedure’s safety.  A 30-year old male patient, previously healthy, presented to our urology outpatient clinic complaining of dull flank pain of six month duration with tenderness in the right renal area and an enlarged right kidney and 1 episode of gross haematuria. Radiological investigations showed left side crossed ectopia with nephrolithiasis. Patient was managed successfully by fluoroscopic guided percutaneous nephrolithotripsy. The position of the stone-containing ectopic kidney can make it easy to reach the pelvis of the target kidney without injuring any adjoining structure. The superimposition of the different soft tissue densities in the radiologic view may limit the ability of the operator to distinguish between different tissue identities. Laparoscopic guidance can represent as a practical solution to this technical problem