Celebrating Economies of Change: Brave Visions for Inclusive Futures

This issue has been inspired by a path-breaking conference held by the Canadian Society for Ecologi-cal Economics (CANSEE), which took place this past May 2019 in Waterloo, Ontario. Entitled Engaging Economies of Change, the conference aimed to ex-pand existing research networks in the economy-environment nexus by building connections beyond the academy in order to meaningfully engage with the practicalities of building and implementing change. This issue captures the rich content shared during the event, as well as descriptions of the pro-cesses and efforts made to create a welcoming and respectful space where academics and community activists could build alliances and discuss common challenges. The conference organizers – all graduate students and activists themselves -- called this ‘building a brave space’.This research was supported by the Social Sciences and Humanities Research Council of Canad

Evidence of a noncoding transcript of the RIPK2 gene overexpressed in head and neck tumor

Receptor-interacting proteins are a family of serine/threonine kinases, which integrate extra and intracellular stress signals caused by different factors, including infections, inflammation and DNA damage. Receptor-interacting serine/threonine-protein kinase 2 (RIP-2) is a member of this family and an important component of the nuclear factor NF-kappa-B signaling pathway. The corresponding human gene RIPK2 generates two transcripts by alternative splicing, the full-length and a short transcript. The short transcript has a truncated 5? sequence, which results in a predicted isoform with a partial kinase domain but able to transduce signals through its caspase recruitment domain. In this study, the expression of RIPK2 was investigated in human tissue samples and, in order to determine if both transcripts are similarly regulated at the transcriptional level, cancer cell lines were submitted to temperature and acid stresses. We observed that both transcripts are expressed in all tissues analyzed, with higher expression of the short one in tumor samples, and they are differentially regulated following temperature stress. Despite transcription, no corresponding protein for the short transcript was detected in tissues and cell lines analyzed. We propose that the shorter transcript is a noncoding RNA and that its presence in the cell may play regulatory roles and affect inflammation and other biological processes related to the kinase activity of RIP-2.Fil: Mancini Villagra, Ulises Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Biotecnología y Biología Molecular. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular; ArgentinaFil: da Cunha, Bianca R.. Universidade de Sao Paulo; BrasilFil: Polachini, Giovana M.. No especifíca;Fil: Tiago, Tiago Henrique. No especifíca;Fil: Carlos H. T. P. da Silva. Universidade de Sao Paulo; BrasilFil: Feitosa, Olavo A.. Universidade de Sao Paulo; BrasilFil: Fukuyama, Erica E.. Arnaldo Vieira de Carvalho Cancer Institute; BrasilFil: López, Rossana V. M.. No especifíca;Fil: Dias Neto, Emmanuel. Universidade de Sao Paulo; BrasilFil: Nunes, Fabio D.. Universidade de Sao Paulo; BrasilFil: Severino, Patricia. Hospital Israelita Albert Einstein; BrasilFil: Tajara, Eloiza Helena Tajara. Universidade de Sao Paulo; Brasi

Aspecto socio-cultural de la transferencia de tecnología de energías renovables en la comunidad terapéutica de Tekové-Rogá

La experiencia realizada en la Comunidad Terapéutica de Tekové-Rogá se encuadra en el Proyecto de Ejecución Práctica y Educación en Energías Renovables y Agua Potable, su implementación depende del Ministerio de Desarrollo Social de la Nación, la Secretaría Nacional de Niñez, Adolescencia y Familia (SENNAF) y la Universidad Tecnológica Nacional (UTN). El objetivo del trabajo es analizar el impacto social que este tipo de experiencias genera, para lograrlo el abordaje metodológico utilizado fue cuanti-cualitativo, en tanto se recolectaron datos estadísticos de la institución que permitieron relevar información sobre su plantel profesional, y cualitativa en tanto indagamos las percepciones que los actores de la institución tienen en relación al proyecto de ejecución en energías renovables. Las conclusiones principales dan cuenta del impacto social en tres ejes diferentes: el impacto a nivel institucional de la comunidad terapéutica, el impacto a nivel socio-cultural y el impacto a nivel académico.The experience realized in Tekové-Rogá's Therapeutic Community is fitted in the Project of Practical Execution and Education in Renewable Energies and Water, his implementation depends on the Department of Social Development of the Nation, the National Secretariat of Childhood, Adolescence and Family (SENNAF) and the Technological National University (UTN). The work analyze the social impact that this type of experiences. The principal conclusions are in three different axes: the first one is related to the impact to institutional level of the therapeutic community, the second one links itself with the impact to socio-cultural level, which can be indirect ó directly. Finally the third axis in which the social impact is identified is to academic level, in which they receive relevancy the innovation in the development of new devices, the role of the university and the impact in the professional identities involved in the project.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES